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Journals / Cukurova Medical Journal / 2013 / Cilt: 38 - Sayı: 3

Effects of Magnetic Field on the Electrophysiological Parameters of Soleus Muscle in Streptozotocin-Induced Diabetic Rats

Streptozotosin ile Deneysel Diyabet Oluşturulan Sıçanların Soleus Kaslarının Elektrofizyolojik Parametrelerine Elektromanyetik Alanın Etkileri

Aykut PELİT
Mustafa EMRE
Ayşe DEMİRKAZIK
İsmail GÜNAY
Pages
426–433
Publication Date
2013-09-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: When group III and IV compared to group I, a significant decrease was found in the RMP (p

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To investigate the effects of magnetic field (MF) on the resting membrane potential and action potential parameters of the Soleus muscle preparations in streptozotocin (STZ) induced diabetic rats.
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Key Findings & Data:The diabetes was induced by a single intravenous injection of STZ (45 mg/kg) in citrate buffer to the jugular vein under the ketamine and xylazine anesthetic combination.
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Conclusion & Impact:Results: When group III and IV compared to group I, a significant decrease was found in the RMP (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Soleus kası · streptozotosin · Dinlenim zar potansiyeli

Abstract

Purpose: To investigate the effects of magnetic field (MF) on the resting membrane potential and action potential parameters of the Soleus muscle preparations in streptozotocin (STZ) induced diabetic rats. Methods: Forty male wistar rats were used in this study. The rats were divided into four groups; Group I (control), Group II (control with magnetic field), group III (diabetic), group IV (diabetic with magnetic field). The diabetes was induced by a single intravenous injection of STZ (45 mg/kg) in citrate buffer to the jugular vein under the ketamine and xylazine anesthetic combination. Resting membrane potential (RMP), muscle action potential (MAP), depolarization and half-repolarization time, MAP integral, depolarization and repolarization rates were recorded by means of the conventional microelectrode technique. Results: When group III and IV compared to group I, a significant decrease was found in the RMP (p

Özet

Amaç: Streptozotosin (STZ) ile deneysel diyabet oluşturulan sıçanlar elektromanyetik alana maruz bırakıldıktan sonra soleus kas preparatlarından dinlenim zar potansiyeli ve kas aksiyon potansiyelinin ölçülerek incelenmesi. Metod: Bu çalışmada 40 adet Wistar türü erkek sıçan kullanıldı. Sıçanlar dört gruba bölündü; Grup I (Kontrol), Grup II (Manyetik alan kontrolü), Grup III (Diyabetik), Grup IV (diyabet uygulanmış manyetik alan grubu). Diyabet tek doz halinde (45 mg/kg ) ketamin ve ksilazin kombinasyon anestezisi altında citrat tamponu içerisine karıştırılmış STZ olarak jügüler venden verildi. Konvensiyonel mikroeletrod tekniği ile dinlenim zar potansiyeli, aksiyon potansiyeli, depolarizasyon ve repolarizasyon süresi, kas aksiyon potansiyeli integrali kayıtlandı. Sonuçlar: Dinlenim zar potansiyeli, Grup I, III ve IV arasında anlamlı bir azalma bulunmuştur (p

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Cite This Article

PELİT, A., EMRE, M., DEMİRKAZIK, A., GÜNAY, İ. (2013). Effects of Magnetic Field on the Electrophysiological Parameters of Soleus Muscle in Streptozotocin-Induced Diabetic Rats. Cukurova Medical Journal, Cilt: 38 - Sayı: 3, 426–433. https://ajindex.com/articles/57116

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