Journals / Kafkas Üniversitesi Veteriner Fakültesi Dergisi / 2019 / Cilt: 25 - Sayı: 2

Phylogenetic Analysis of Bovine Respiratory Syncytial Virus from Calves with Respiratory Disorders

Solunum Sistemi Hastalığı Olan Buzağılarda Saptanan Bovine Respiratory Syncytial Virusun Filogenetik Analizi

Pages
251–256
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This study onthe molecular characterization of BRSV circulating in calves would contribute for future studies on the epidemiology of this infection and thedevelopment and/or choice the effective vaccines in Turkey.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Bovine respiratory disease (BRD) causes economic losses related to a reduction in weight gain of affected animals, veterinary treatment costs,death, etc.
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Key Findings & Data:One of the important respiratory tract disease viruses is the bovine respiratory syncytial virus (BRSV).
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Conclusion & Impact:This study onthe molecular characterization of BRSV circulating in calves would contribute for future studies on the epidemiology of this infection and thedevelopment and/or choice the effective vaccines in Turkey.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Bovine respiratory disease (BRD) causes economic losses related to a reduction in weight gain of affected animals, veterinary treatment costs,death, etc. One of the important respiratory tract disease viruses is the bovine respiratory syncytial virus (BRSV). In this study, it is aimed toreport the molecular characterization of detected BRSVs. Therefore, nasal samples from three calves in a herd seen severe respiratory disorderswere examined for BRSV and other possible viral etiological agents by PCRs and the amplicons were sequenced. In the phylogenetic tree,BRSV circulating in this herd is clustered with the genetic subgroup III BRSVs deposited in GenBank from some other countries. This study onthe molecular characterization of BRSV circulating in calves would contribute for future studies on the epidemiology of this infection and thedevelopment and/or choice the effective vaccines in Turkey.

Özet

Sığırlarda solunum sistemi hastalıkları, etkilenen hayvanların kilo alımında azalma, veteriner tedavi masrafları, ölüm gibi sebeplerle ekonomik kayıplara neden olmaktadır. Bovine Respiratory Syncytial Virus (BRSV), solunum sistemini etkileyen viral etkenlerin başında gelmektedir. Bu çalışmada BRSV’nin saptanması ve tespit edilen etkenlerin moleküler karakterizasyonlarının ortaya konulması amaçlanmıştır. Bu amaçla, buzağılarda ağır solunum yolu sistemi bulguları gözlenen bir işletmedeki üç buzağıdan alınan burun akıntısı örnekleri BRSV ve diğer viral etkenler yönünden PCR ile test edilmiştir. RT-PCR sonucunda pozitif bulunan örneklerin dizin bilgileri elde edilmiştir. Yapılan filogenetik analiz sonucunda bu sürüde tespit edilen BRSV’nin genetik olarak subgrup III içerisinde yer aldığı ortaya konulmuştur. Buzağılarda saptanan BRSV’nin moleküler karakterizasyonu üzerine yapılan bu çalışma, bu enfeksiyonun epidemiyolojisi ve etkili aşıların geliştirilmesi ve/veya seçimiyle ilgili gelecekteki çalışmalara katkıda bulunacaktır.

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Cite This Article

COŞKUN, N., ALKAN, F., HACIOĞLU, İ. K., YELKEN, S. D., SEVİNÇ, S. (2022). Phylogenetic Analysis of Bovine Respiratory Syncytial Virus from Calves with Respiratory Disorders. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 25 - Sayı: 2, 251–256. https://ajindex.com/articles/569705

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