Journals / Kafkas Üniversitesi Veteriner Fakültesi Dergisi / 2021 / Cilt: 27 - Sayı: 5

Haematological Profile After Use of Titanium Double Shanked Ligation Clips in Laparoscopic Appendectomy: An Experimental Study on Rat Model

Laparoskopik Apendektomide Titanyum Çift Uçlu Ligasyon Klipslerinin Kullanımı Sonrası Hematolojik Profil: Ratlar Modelinde Deneysel Bir Çalışma

Pages
609–616
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

From a haematological standpoint, DS clips are more applicable for potential patients than endoloop polyglactin 910 ligatures

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of the study was to determine possible adverse effects on haematological parameters of the rats, using different surgical techniques, i.e. titanium double shanked ligation (DS) clips and endoloop polyglactin 910 suture material in laparoscopic appendectomy.
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Key Findings & Data:Fifty rats were randomized into three groups: group 1 in which the appendiceal base was closed with a endoloop polyglactin 910 ligatures, 20 rats, group 2 in which the appendectomy was closed with DS titanium clips, 20 rats.
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Conclusion & Impact:From a haematological standpoint, DS clips are more applicable for potential patients than endoloop polyglactin 910 ligatures
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aim of the study was to determine possible adverse effects on haematological parameters of the rats, using different surgical techniques, i.e. titanium double shanked ligation (DS) clips and endoloop polyglactin 910 suture material in laparoscopic appendectomy. The use of DS clips and other similar methods is not widely represented in veterinary surgery, as is the case in humans. Fifty rats were randomized into three groups: group 1 in which the appendiceal base was closed with a endoloop polyglactin 910 ligatures, 20 rats, group 2 in which the appendectomy was closed with DS titanium clips, 20 rats. Group 3 was the control, in which the animals were not subjected to the surgical procedure, 10 rats. Blood was drawn from the caudal vein of ten animals from each experimental group, 7 and 28 days post-surgery. Thrombocytopenia was found in the DS clips group, and hypochromia with hypochromic erythrocytes, as well as neutrophilia and lymphopenia in both experimental groups. From a haematological standpoint, DS clips are more applicable for potential patients than endoloop polyglactin 910 ligatures

Özet

Bu çalışmada, ratlarda laparoskopik apendektomide titanyum çift uçlu ligasyon (DS) klipsleri ve endoloop poliglaktin 910 sütür materyali gibi farklı cerrahi teknikler kullanılarak hematolojik parametreler üzerine olası olumsuz etkilerinin belirlenmesi amaçlanmıştır. DS klipslerinin ve diğer benzer yöntemlerin kullanımı, insanlarda olduğu gibi veteriner cerrahisinde yaygın kullanım alanı bulmamaktadır. Elli rat rastgele üç gruba ayrılmış: Grup 1’de (n=20 rat), apendiks tabanının bir endoloop poliglaktin 910 ligatür ile kapatıldığı apendektomi, Grup 2’de (n=20 rat) DS titanyum klipslerle kapatıldığı apendektomi uygulanmıştır. Grup 3 (n=10 rat), ratların cerrahi işleme tabi tutulmadığı kontrol grubunu oluşturmuştur. Cerrahi işlemden 7 ile 28 gün sonra her deney grubundan on hayvanın kaudal damarlarından kan alınmış. DS klips uygulanan grupta trombositopeni ve her iki deney grubunda hipokromik eritrositlerle birlikte hipokromi ve ayrıca nötrofili ve lenfopeni saptanmış. Hematolojik açıdan, DS klipsleri potansiyel hastalar için endoloop poliglaktin 910 ligatürlerinden daha uygundur.

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Cite This Article

AHMED, N. H., BAJRIĆ, A., KATICA, M., SMAJOVIĆ, A., KATICA, A., SIVIĆ, M., RUKAVINA, D., ZAHIROVIĆ, A., BAJRIĆ, A., ČELEBIČIĆ, M., DELIBEGOVIĆ, S. (2022). Haematological Profile After Use of Titanium Double Shanked Ligation Clips in Laparoscopic Appendectomy: An Experimental Study on Rat Model. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 27 - Sayı: 5, 609–616. https://ajindex.com/articles/569503

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