Evaluation of Blink Reflex in Patients with Steatosis

Conclusion: There is a slowdown of the BR in the steatosis stage; therefore, by performing the BR, neuropathy can be detected at an early stage in patients with steatosis.

📌 3 Key Takeaways

🎯

Objective & Hypothesis:Purpose: The blink reflex (BR) is a useful electrodiagnostic method for evaluating neuropathies.

📊

Key Findings & Data:Material and Methods: A total of 86 subjects were enrolled in this study: 56 patients (29 female, 27 male) with simple steatosis and 30 healthy controls (17 female, 13 male).

💡

Conclusion & Impact:Conclusion: There is a slowdown of the BR in the steatosis stage; therefore, by performing the BR, neuropathy can be detected at an early stage in patients with steatosis.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Blink refleks · nöropati · steatoz

Abstract

Purpose: The blink reflex (BR) is a useful electrodiagnostic method for evaluating neuropathies. The aim of our study was to investigate the role of the BR in the early diagnosis of neuropathy in simple steatosis. Material and Methods: A total of 86 subjects were enrolled in this study: 56 patients (29 female, 27 male) with simple steatosis and 30 healthy controls (17 female, 13 male). After the electrical stimulation of the supraorbital nerve, two responses in the orbicularis oculi muscle occur, the early ipsilateral response and the late bilateral response latencies, which were recorded. Results: The triglyceride levels and lipid accumulation products were higher in the patients with steatosis than in the controls. When compared to the control group, the patient group had early right ipsilateral latency, late right ipsilateral latency, late right contralateral latency, early left ipsilateral latency, late left ipsilateral latency, and late left contralateral latency. Conclusion: There is a slowdown of the BR in the steatosis stage; therefore, by performing the BR, neuropathy can be detected at an early stage in patients with steatosis.

Özet

Amaç: Blink refleks (BR) nöropatileri değerlendirmek için kullanılan yararlı bir elektrodiagnostik yöntemdir. Biz bu çalışmada basit steatozda nöropatinin erken tanısında BR’in rolünü incelemeyi amaçladık. Materyal ve Metod: Çalışmaya basit steatozlu 56 hasta (29 kadın, 27 erkek) ve 30 sağlıklı kontrol (17 kadın, 13 erkek) olmak üzere toplam 86 kişi dahil edildi. Supraorbital sinirin elektriksel uyarımından sonra orbikularis okuli kasında ortaya çıkan iki cevap, erken ipsilateral cevap ve geç bilateral cevap gecikme zamanları kaydedildi. Bulgular: Trigliserid düzeyi ve lipid akümülasyon skoru steatozlu hastalarda kontrol grubundan daha yüksekti. Kontrol grubuyla karşılaştırıldığında hasta grubunda erken sağ ipsilateral gecikme, geç sağ ipsilateral gecikme, geç sağ kontralateral gecikme, erken sol ipsilateral gecikme, geç sol ipsilateral gecikme ve geç sol kontralateral gecikme zamanı uzundu. Sonuç: Steatoz aşamasında BR’de yavaşlama vardır. Steatozlu hastalarda BR ölçülerek nöropati gelişimi erken aşamada tespit edilebilir

Keywords

Blink refleks nöropati steatoz non-alkolik yağlı karaciğer hipertrigliseridemi Blink reflex neuropathy steatosis non-alcoholic fatty liver disease hypertriglyceridemia

🔖

Cite This Article

CÜRE, E., KIRBAŞ, S., CÜRE, M., TÜFEKÇİ, A., KIRBAŞ, A., YÜCE, S., OĞULLAR, S. (2015). Evaluation of Blink Reflex in Patients with Steatosis. Cukurova Medical Journal, Cilt: 40 - Sayı: 4, 714–722. https://ajindex.com/articles/56854

📄 Full Text PDF Viewer

Open in New Tab ↗

↗New Tab

📄

PDF görüntüleyici hazırlanıyor...

References (11)

Smith AG. Impaired glucose tolerance and metabolic syndrome in idiopathic neuropathy. J Peripher Nerv Syst. 2012;17:15-21.
Lupachyk S, Watcho P, Hasanova N, Julius U, Obrosova IG. Triglyceride, nonesterified fatty acids, and prediabetic neuropathy: role for oxidative- nitrosative stress. Free Radic Biol Med. 2012;52:1255-63.
Pirgon Ö, Bilgin H, Çekmez F, Kurku H, Dündar BN. Association Between Insulin Resistance and Oxidative Stress Parameters in Obese Adolescents with Non-Alcoholic Fatty Liver Disease. J Clin Res Pediatr Endocrinol. 2013;5:33-9. Day CP. Clinical spectrum and therapy of non- alcoholic steatohepatitis. Dig Dis. 2012;30:69-73.
Alexander J, Torbenson M, Wu TT, Yeh MM. Non- alcoholic fatty liver disease contributes to hepatocarcinogenesis in non-cirrhotic liver: A clinical and pathological study. J Gastroenterol Hepatol. 2013;28:848-54.
Tran A, Gual P. Non-alcoholic steatohepatitis in morbidly obese patients. Clin Res Hepatol Gastroenterol. 2013;37:17-29.
Kasturiratne A, Weerasinghe S, Dassanayake AS, Rajindrajith S, de Silva AP, Kato N, et al. Influence of non-alcoholic fatty liver disease on the development of diabetes mellitus. J Gastroenterol Hepatol. 2013;28:142-7.
Zdunska A, Cegielska J, Kochanowski J. Variability of the blink reflex in patients with migraine. Neurol Neurochir Pol. 2013;47:352-6. Kimura J. The blink reflex. In: Kimura J, editor. Electrodiagnosis in Diseases of Muscle and Nerve. New York, Oxford, 2001;3:409-38. Valls-Sole J. Assessment of excitability in brainstem circuits mediating the blink reflex and the startle reaction. Clin Neurophysiol. 2012;123:13-20.
Preston DC, Shapiro BE. Blink Reflex. In: Preston DC, Shapiro BE, editors. Electromyography & Disorders Clinical-Electrophysiologic Correlations. United States, Elsevier, 2005;2:59-64.
Leon L, Casanova-Molla J, Lauria G, Valls-Sole J. The somatosensory blink reflex in upper and lower brainstem lesions. Muscle Nerve. 2011;43:196-202.
Gokcel A, Ozsahin AK, Sezgin N, Karakose H, Ertorer ME, Akbaba M, et al. High prevalence of diabetes in Adana, a southern province of Turkey. Diabetes Care. 2003;26:3031-4.
Bedogni G, Kahn HS, Bellentani S, Tiribelli C. A simple index of lipid overaccumulation is a good marker of liver steatosis. BMC Gastroenterol. 2010;10:98. Schwenzer NF, Springer F, Schraml C, Stefan N, Machann J, Schick F. Non-invasive assessment and quantification of liver steatosis by ultrasound, computed tomography and magnetic resonance. J Hepatol. 2009;51:433–4