Journals / Journal of the Turkish-German Gynecological Association / 2005 / Cilt: 6 - Sayı: 4

Factors associated with lymph node involvement in epithelial ovarian cancer

Epitelyal over kanserinde lenf nodu tutulumuna etki eden faktörler

Pages
272–274
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The increase in the age of the patient increases lymphatic invasion of the tumor.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To investigate risk factors associated with lymph node involvement in patients with epithelial ovarian cancer.
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Key Findings & Data:Materials and Methods: Fourteen patients with ovarian cancer, who were operated at our clinic, were included.
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Conclusion & Impact:The increase in the age of the patient increases lymphatic invasion of the tumor.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To investigate risk factors associated with lymph node involvement in patients with epithelial ovarian cancer. Materials and Methods: Fourteen patients with ovarian cancer, who were operated at our clinic, were included. Forward conditional logistic regression was used to examine the relationship between histological involvement of pelvic or para-aortic lymph nodes during surgery, and age, parity, presence of ascites, nuclear grade, histological grade, tumor size, and various tumor markers. Univariate analyses were performed using Student’s t-test. Results: Increasing age was significantly correlated with both pelvic (p=0.01) and para-aortic (p=0.01) lymph node metastasis in univariate and logistic regression analyses. No other variable was independently associated with lymph node involvement. Conclusion: Lymph node involvement is an important factor for 5-year survival rate in epithelial ovarian cancer. The increase in the age of the patient increases lymphatic invasion of the tumor.

Özet

Amaç: Epitelyal over kanserli hastalarda lenf nodu tutulumu ile ilişkili faktörleri araştırmak. Materyal ve Metot: Kliniğimizde ameliyat edilen epitelyal over kanserli 14 hasta çalışmaya alındı. Cerrahi sonrasında elde edilen pelvik ve para-aortik lenf nodlarının histopatolojik olarak pozitifliği ile yaş, parite, asit varlığı, nükleer grade, histolojik grade, tümör belirteçlerinin seviyeleri ve tümör büyüklüğü arasındaki ilişki “forward conditional lojistik regresyon” kullanılarak araştırıldı. Çalışmada “univariate” analiz için Student’s t testi kullanıldı. Sonuçlar: Lojistik regresyon ve “univariate” analizde yaş artışı ile hem pelvik, hem de para-aortik lenf nodu tutulumu arasında anlamlı ilişki bulundu (sırasıyla, p=0.01 ve p=0.01). Lenf nodu tutulumu ile diğer faktörler ilişkili değildi. Tartışma: Epitelyal over kanserinde lenfatik tutulum varlığı 5 yıllık sağkalım açısından önemlidir ve yaş artışı lenfatik yayılım riskinde artışıa yol açmaktadır.

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Cite This Article

ÖZKAYA, O., TOROS, Ü. D., SEZİK, M., KAYA, H. (2022). Factors associated with lymph node involvement in epithelial ovarian cancer. Journal of the Turkish-German Gynecological Association, Cilt: 6 - Sayı: 4, 272–274. https://ajindex.com/articles/568062

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