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Journals / Journal of the Turkish-German Gynecological Association / 2007 / Cilt: 8 - Sayı: 3

Düşük gradlı skuamöz intraepitelyal lezyon ve normal serviksin ayırıcı tanısında Ki-67 immun boyamanın değerlendirilmesi

Evaluation of Ki-67 immunostaining in the differential diagnosis of low grade squamous intraepithelial lesion and normal cervix

Sema Dilek ARICI
Şahande ELAGÖZ
Gonca İMİR
Gülay ŞİMŞEK
Meral ÇETİN
Hatice ÖZER
Pages
285–289
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Ki-67 index was higher in low-grade SILs (p

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Ki-67 immunostaining is a diagnostic adjunctive test used in the differential diagnosis of squamous intraepithelial lesions (SILs) of the cervix.
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Key Findings & Data:The aim of this study was to determine Ki-67 index and Ki 67-positive cell cluster for distinguishing normal cervix and low-grade squamous intraepithelial lesions (low-grade SILs).MATERIAL-METHOD: Thirty-four cervical specimens, in which 17cases were previously diagnosed as normal cervix and 17 cases were low-grade SILs, included in the study.
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Conclusion & Impact:Ki-67 index was higher in low-grade SILs (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Ki-67 immunostaining is a diagnostic adjunctive test used in the differential diagnosis of squamous intraepithelial lesions (SILs) of the cervix. The aim of this study was to determine Ki-67 index and Ki 67-positive cell cluster for distinguishing normal cervix and low-grade squamous intraepithelial lesions (low-grade SILs).MATERIAL-METHOD: Thirty-four cervical specimens, in which 17cases were previously diagnosed as normal cervix and 17 cases were low-grade SILs, included in the study. Ki-67 immunohistochemical staining was performed using avidin biotin complex.RESULTS: After reevaluating the cases by means of histo-pathological and Ki-67 immunostaining features, 21 of 34 cases were diagnosed as normal cervix and 13 were diagnosed as low-grade SILs. Ki-67 index was higher in low-grade SILs (p

Özet

AMAÇ: Ki-67 immun boyaması serviksin skuamöz intraepitelyal lezyonlarda (SIL) ayırıcı tanısında kullanılan tanısal bir testtir. Bu çalışmanın amacı Low-grade SIL ve normal serviksin ayırıcı tanısında Ki-67 indeksini ve Ki-67 pozitif hücre kümelerinin belirlemektir. MATERYAL-METOD: Çalışmada patolojik incelemede 17’si önceden normal serviks, diğer 17’si low-grade SIL tanısı konmuş toplam 34 servikal örnek Ki-67 immunohistokimyasal boyaması yapıldı. SONUÇLAR: Örnekler histo-patolojik olarak ve Ki-67 immun boyaması ile tekrar değerlendirdikten sonra 34 örneğin 21’inde normal serviks ve 13’ünde low-grade SIL tanısı kondu. Ki-67 indeksi low-grade SIL olgularında anlamlı olarak yüksek idi (p

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Cite This Article

ARICI, S. D., ELAGÖZ, Ş., İMİR, G., ŞİMŞEK, G., ÇETİN, M., ÖZER, H. (2022). Düşük gradlı skuamöz intraepitelyal lezyon ve normal serviksin ayırıcı tanısında Ki-67 immun boyamanın değerlendirilmesi. Journal of the Turkish-German Gynecological Association, Cilt: 8 - Sayı: 3, 285–289. https://ajindex.com/articles/567915

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