Journals / Journal of the Turkish-German Gynecological Association / 2011 / Cilt: 12 - Sayı: 1

PPROM yönetiminde uzamış intravajinal klindamisin kremin ampisilinle birlikte kullanımı - bir olgu sunumu

Prolonged usage of intravaginal clindamycin cream combined with ampicillin for the management of PPROM - a case report

Pages
124–126
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We concluded that expectant active management of PPROM with antibiotics may be a suitable treatment option in carefully selected patients after receiving the patient’s approval.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Prolonged PPROM may be catastrophic both for the mother and fetus due to ascending infections.
📊
Key Findings & Data:We aimed to describe maternal and neonatal outcomes in expectant management of PPROM beginning from the 24th gestational week (GW) of pregnancy up to the 34th week under treatment with continuous usage of intravaginal clindamycin cream.
💡
Conclusion & Impact:We concluded that expectant active management of PPROM with antibiotics may be a suitable treatment option in carefully selected patients after receiving the patient’s approval.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Prolonged PPROM may be catastrophic both for the mother and fetus due to ascending infections. The decision was expectant management in the setting of a spontaneous preterm premature rupture of membranes (PPROM) case and the prevention of chorioamnionitis was essential. We aimed to describe maternal and neonatal outcomes in expectant management of PPROM beginning from the 24th gestational week (GW) of pregnancy up to the 34th week under treatment with continuous usage of intravaginal clindamycin cream. We concluded that expectant active management of PPROM with antibiotics may be a suitable treatment option in carefully selected patients after receiving the patient’s approval. Intravaginal clindamycin cream may be combined with systemic antibiotics (ampicillin and erythromycin) and may be a maintenance single drug for the prophylaxis of ascending vaginal infections. (J Turkish-German Gynecol Assoc 2011; 12: 124-6)

Özet

Uzamış PPROM asendan enfeksiyonlara bağlı anne ve bebek için oldukça kötü sonuçlar doğurabilmektedir. Spontan preterm ve prematür membran rüptürü (PPROM) ile müracaat eden olgumuzda, gelişebilecek koryoamnionit riskine karşı korunma zorunlu olup tedavi yaklaşımı ekspektan yönetim olarak belirlenmiştir. Amacımız 24. gebelik haftasında PPROM ile müracaat eden olgunun, 34. gebelik haftasına kadar intravajinal klindamisin kremin sürekli kullanımı ile takibi ve maternal, neonatal sonuçlarını tariflemektir. Sonuç olarak, PPROM olgularında antibiyotikler ile ekspektan aktif yönetim, dikkatli seçilmiş ve onamı alınmış olgularda uygun tedavi yaklaşımı olabilir. Asendan enfeksiyonlardan korunmada vajinal klindamisin sistemik antibiyotiklerle (ampisilin ve eritromisin) kombine tercih edilebileceği gibi idame tedavide tek ajan olarakta kullanılabilir. (J Turkish-German Gynecol Assoc 2011; 12: 124-6)

🔖

Cite This Article

AYDOĞAN, Ü., KARAŞAHİN, K. E., ERCAN, C. M., BAŞER, İ., ALANBAY, İ. (2022). PPROM yönetiminde uzamış intravajinal klindamisin kremin ampisilinle birlikte kullanımı - bir olgu sunumu. Journal of the Turkish-German Gynecological Association, Cilt: 12 - Sayı: 1, 124–126. https://ajindex.com/articles/567719

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. Soraisham AS, Singhal N, McMillan DD, Sauve RS, Lee SK; Canadian Neonatal Network. A multicenter study on the clinical outcome of chorioamnionitis in preterm infants. Am J Obstet Gynecol 2009; 200: 372. [CrossRef] 2. Silver HM, Sperling RS, St Clair PJ, Gibbs RS. Evidence relating bacterial vaginosis to intraamniotic infection. Am J Obstet Gynecol 1989; 161: 808-12. 3. Goldenberg RL. The management of preterm labor. Obstet Gynecol 2002; 100: 1020-37. [CrossRef] 4. Park JS, Yoon BH, Romero R, Moon JB, Oh SY, Kim JC, et al. The relationship between oligohydramnios and the onset of preterm labor in preterm premature rupture of membranes. Am J Obstet Gynecol 2001; 184: 459-62. [CrossRef] 5. Huang S, Qi HB, Li L. Residue amniotic fluid volume after preterm premature rupture of membranes and maternal-fetal outcome. Zhonghua Fu Chan Ke Za Zhi 2009; 44: 726-30. 6. Aagaard-Tillery KM, Nuthalapaty FS, Ramsey PS, Ramin KD. Preterm premature rupture of membranes: perspectives surrounding controversies in management. Am J Perinatol 2005; 22: 287-97. [CrossRef] 7. Hutzal CE, Boyle EM, Kenyon SL, Nash JV, Winsor S, Taylor DJ, et al. Use of antibiotics for the treatment of preterm parturition and prevention of neonatal morbidity: a metaanalysis. Am J Obstet Gynecol 2008; 199: 1-8. [CrossRef] 8. Kermalli MS, Oğuz S, Danışman N, Gökmen O. Preterm Prematür Membran Rüptürlü Gebelerde Feto-Maternal Enfeksiyonun Erken Tahmininde Seri Nonstress Test (NST) Takibinin Rolü. Turkiye Klinikleri J Gynecol Obst 2000; 10: 91-7. 9. Kenyon, S, Boulvain, M, Neilson, J. Antibiotics for preterm rupture of membranes. Cochrane Database Syst Rev 2003; CD001058. 10. Yudin MH, van Schalkwyk J, Van Eyk N, Boucher M, Castillo E, Cormier B, et al. Society of Obstetricians and Gynaecologists of Canada. Antibiotic therapy in preterm premature rupture of the membranes. J Obstet Gynaecol Can 2009; 31: 868-74. 11. Lamont RF. The role of infection in preterm labour and birth. Hosp Med 2003; 64: 644-7. [CrossRef] 12. Amsel R, Totten PA, Spiegel CA, Chen KC, Eschenbach D, Holmes KK. Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations. Am J Med 1983; 74: 14-22. [CrossRef] 13. McDonald HM, Brocklehurst P, Gordon A. Antibiotics for treating bacterial vaginosis in pregnancy. Cochrane Database Syst Rev 2007; 24: CD000262. 14. Philipson A, Sabath LD, Charles D. Transplacental passage of erythromycin and clindamycin. N Engl J Med 1973; 288: 1219-21. [CrossRef]