Journals / Journal of the Turkish-German Gynecological Association / 2012 / Cilt: 13 - Sayı: 3

Depo rFSH yerleştirmenin yeni bir yolu: canlı doğumla sonuçlanan IVF/ICSI döngüsünde bir ciddi enjeksiyon hatası olgusu

A new way of setting rFSH deposit: a case of severe injection error in IVF/ICSI cycle ending with live birth

Pages
215–217
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In the case of injection errors,continuing stimulation protocol seems to be achievable in certaincases considering hormone levels and the process of follicle growth.(J Turkish-German Gynecol Assoc 2012; 13: 215-7)

📌 3 Key Takeaways

🎯
Objective & Hypothesis:We present a case with a severe injection error: a 25- year old womanwith secondary infertility caused by a male factor was enrolled in ourIVF/ICSI-ET program.
📊
Key Findings & Data:The rFSH dose per day was 900 IU-0IU-0 IU-0 IU.
💡
Conclusion & Impact:In the case of injection errors,continuing stimulation protocol seems to be achievable in certaincases considering hormone levels and the process of follicle growth.(J Turkish-German Gynecol Assoc 2012; 13: 215-7)
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

We present a case with a severe injection error: a 25- year old womanwith secondary infertility caused by a male factor was enrolled in ourIVF/ICSI-ET program. Stimulation was performed in a long- protocoland ovarian stimulation, using rFSH follitropin beta, starting on thethird day of the menstrual cycle. The rFSH dose per day was 900 IU-0IU-0 IU-0 IU. Due to normal ovarian response and follicle growth, stimulation was continued and there was no detriment in oocyte qualityand no symptoms of OHSS. Following blastocyte transfer cesareansection was unpreventable at 37+5 weeks of gestation due to an impacted transverse lie. Different stimulation protocols are needed forappropriate treatment of various patients provided that the administration of treatment was done correctly. In the case of injection errors,continuing stimulation protocol seems to be achievable in certaincases considering hormone levels and the process of follicle growth.(J Turkish-German Gynecol Assoc 2012; 13: 215-7)

Özet

Ciddi enjeksiyon hatası olan bir olgu sunuyoruz: Erkek faktörünün yol açtığı ikincil infertilitesi olan 25 yaşındaki bir kadın IVF/ICSI-ET programımıza alındı. Stimulasyon uzun protokol ile gerçekleştirildi ve over stimulasyonu, rFSH follitropin beta kullanılarak, menstrüel döngünün üçüncü günü başlatıldı. Günlük rFSH dozu şöyleydi: 900 IU-0 IU-0 IU-0 IU. Normal over yanıtı ve folikül büyümesi nedeniyle stimulasyona devam edildi, oosit kalitesinde bozulma ve OHSS semptomları yoktu. Blastokist transferini takiben sezaryenle doğum, kalıcı transvers duruş nedeniyle 37+5inci gebelik haftasında önlenemez durumdaydı. Çeşitli hastaların uygun tedavisi için, tedavi uygulamasının doğru bir şekilde yapılmasını sağlayan, farklı stimulasyon protokollerine gerek duyulmaktadır. Enjeksiyon hataları durumunda, hormon düzeyleri ve folikül büyümesi süreci göz önüne alınarak, stimulasyon protokolünün sürdürülmesi bazı olgularda başarılabilir görünmektedir.(J Turkish-German Gynecol Assoc 2012; 13: 215-7)

🔖

Cite This Article

TEWS, G., SHEBL, O., MAYER, R. B., EBNER, T. (2022). Depo rFSH yerleştirmenin yeni bir yolu: canlı doğumla sonuçlanan IVF/ICSI döngüsünde bir ciddi enjeksiyon hatası olgusu. Journal of the Turkish-German Gynecological Association, Cilt: 13 - Sayı: 3, 215–217. https://ajindex.com/articles/567678

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (3)

  1. Oddens BJ, Tonkelaar I, Nieuwenhuyse H. Psychosocial experi- ences in woman facing fertility problems - a comparative survey. Hum Reprod 1999; 14: 255-61. [CrossRef] Huisman D, Raymakers X, Hoomans EHM. Understanding the bur- den of ovarian stimulation: fertility expert and patient perceptions. RBM Online 2009; 19: 5-10.
  2. Ebner T, Balaban B, Moser M, Shebl O, Urman B, Ata B, et al. Automatic user-independent zona pellucida imaging at the oocyte stage allows for the prediction of preimplantation development. Fertil Steril 2010; 94: 913-20. [CrossRef] Otsuki J, Okada A, Morimoto K, Nagai Y, Kubo H. The relationship between pregnancy outcome and smooth endoplasmic reticulum clusters in MII human oocytes. Hum Reprod 2004; 19: 1591-7. [CrossRef] Mannaerts BMJL, Rombout F, Out HJ, Coelingh Bennink H. Clinical profiling of recombinant follicle stimulating hormone (rFSH; Puregon): relationship between serum FSH and efficacy. Hum Reprod 1996; 2: 153-61. [CrossRef] Mannaerts BMJL, Shoham Z, Schoot D, Bouchard P, Harlin J, Fauser BCJM, et al. Single- dose pharmacokinetics and pharmacodynam- ics of recombinant human follicle-stimulating hormone (Org 32489) in gonadotropin-deficient volunteers. Fertil Steril 1998; 69: 15-20. [CrossRef] La Marca A, Giulini S, Tirelli A, Berucci E, Marsella T, Xella S, Volpe A. Anti-Müllarian hormone measurement on any day of the men- strual cycle strongly predicts ovarian response in assisted repro- ductive technology. Hum Reprod 2007; 22: 766-71. [CrossRef] Jayaprakasan K, Campbell B, Hopkisson J, Johnson I, Rain-Fenning N. A prospective, comparative analyses of anti-Müllarian hormone, inhibin-B, and three-dimensional ultrasound determinants of ovar- ian reserve in the prediction of poor response to controlled ovarian stimulation. Fertil Steril 2010; 93: 855-64. [CrossRef] Shebl O, Ebner T, Sir A, Scheier-Lechner E, Mayer RB, Tews G, et al. Age- related distribution of basal serum AMH level in woman of reproductive age and a presumable healthy cohort. Fert Stert 2011; 95: 832-4. [CrossRef] Navot D, Bergh PA, Laufer N. Ovarian hyperstimulation syndrome in novel reproductive technologies: prevention and treatment. Fertil Steril 1992; 58: 249-61.
  3. Delvigne A, Demoulin A, Smitz J, Donnez J, Koninckx P, Dohnt M, et al. The ovarian hyperstimulation syndrome in in-vitro fertilization: a Belgian multicentric study. I. Clinical and biological features. Hum Reprod 1993; 8: 1353-60. Aboulghar M. Prediction of ovarian hyperstimulation syndrome (OHSS