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Journals / Journal of the Turkish-German Gynecological Association / 2012 / Cilt: 13 - Sayı: 4

Uzun süreli nikotine maruziyetin nikotin bağımlılığına ve fetüsün büyümesine etkisi

The effect of long term nicotine exposure on nicotine addiction and fetal growth

Gülinnaz ERCAN
Volkan TURAN
Soycan MIZRAK
Mustafa Coşan TEREK
Pages
237–241
Publication Date
2022-10-18
DOI
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Meanwhile, pups of theNG continued to receive 0.4 mg/kg/day nicotine for 12 months whilehe controls continued with normal drinking water.Results: At the end of the 6th week, it was determined that 30 (69%)rats out of 43 in the NG and only 7 rats (20%) out of 35 in the controlgroup preferred the nicotine added drinking water (p

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Objective & Hypothesis:Objective: To investigate the effect of nicotine exposure starting be ore coitus and continuing during pregnancy and lactation period ondelivery rate, fetal growth and nicotine addiction in rats.Material and Methods: Ten female Swiss Albino rats were dividednto 2 groups as the nicotine group (NG) (n=5), and the control group(n=5), conceived by adding 2 male rats to each group.
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Key Findings & Data:While thecontrol group was given only normal drinking water, 0.4 mg/kg bodyweight (BW)/day nicotine was given to the NG in drinking water.
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Conclusion & Impact:Meanwhile, pups of theNG continued to receive 0.4 mg/kg/day nicotine for 12 months whilehe controls continued with normal drinking water.Results: At the end of the 6th week, it was determined that 30 (69%)rats out of 43 in the NG and only 7 rats (20%) out of 35 in the controlgroup preferred the nicotine added drinking water (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To investigate the effect of nicotine exposure starting be ore coitus and continuing during pregnancy and lactation period ondelivery rate, fetal growth and nicotine addiction in rats.Material and Methods: Ten female Swiss Albino rats were dividednto 2 groups as the nicotine group (NG) (n=5), and the control group(n=5), conceived by adding 2 male rats to each group. While thecontrol group was given only normal drinking water, 0.4 mg/kg bodyweight (BW)/day nicotine was given to the NG in drinking water. Afterdelivery, the BWs of pups were recorded weekly for 6 weeks and theirdrinking water preferences were assessed. Meanwhile, pups of theNG continued to receive 0.4 mg/kg/day nicotine for 12 months whilehe controls continued with normal drinking water.Results: At the end of the 6th week, it was determined that 30 (69%)rats out of 43 in the NG and only 7 rats (20%) out of 35 in the controlgroup preferred the nicotine added drinking water (p

Özet

Amaç: Sıçanlarda koitusdan önce başlayıp gebelik boyunca ve lakasyon döneminde devam eden nikotin maruziyetinin doğum oranı, etal büyüme ve nikotin bağımlılığına olan etkilerinin araştırılması Gereç ve Yöntemler: On dişi Swiss Albino sıçan kontrol grubu (n=5) ve nikotin grubu (n=5) olarak iki gruba ayrıldı ve aralarına 2 erkek sıçan eklenerek gebe kalmaları sağlandı. Kontrol grubuna normal çme suyu verilirken, nikotin grubuna içme suyu içerisinde 0.4 mg/ kg vücut ağırlığı/gün nikotin eklendi. Doğumdan sonra yavru ratların vücut ağırlıkları, 6 hafta boyunca haftalık kaydedildi ve su tercihleri değerlendirildi. Bu arada nikotin grubunun yavru sıçanları 0.4 mg/kg/ gün nikotin 12 ay boyunca devam ederken, kontroller normal içme suyuna devam etti. Bulgular: Altı hafta sonunda nikotin grubundaki 43 sıçanın 30u (%69) ve kontrol grubundaki 35 sıçanın 7si (%20) nikotin eklenmiş suyu tercih etti (p

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Cite This Article

ERCAN, G., TURAN, V., MIZRAK, S., TEREK, M. C. (2022). Uzun süreli nikotine maruziyetin nikotin bağımlılığına ve fetüsün büyümesine etkisi. Journal of the Turkish-German Gynecological Association, Cilt: 13 - Sayı: 4, 237–241. https://ajindex.com/articles/567675

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