Journals / Journal of the Turkish-German Gynecological Association / 2012 / Cilt: 13 - Sayı: 4

Doğum eylemi indüksiyonunda kullanılan intravajinal dinoproston ve oksitosin in umblikal arter kan gazı parametreleri üzerine etkilerinin karşılaştırılması

Effects of intravaginally inserted controlled-release dinoprostone and oxytocin for labor induction on umbilical cord blood gas parameters

Pages
257–260
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Induction of labor with either oxytocin or dinoprostone in women with uncomplicated term pregnancies had no adverse effects on umbilical artery blood gas parameters. (J Turkish-German Gynecol Assoc 2012; 13: 257-60)

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To compare the effects of oxytocin and dinoprostone used in labor induction on fetal blood gas parameters.
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Key Findings & Data:Material and Methods: This prospective randomized trial involved 108 women who completed 37 gestational weeks and who required labor induction prior to normal vaginal birth.
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Conclusion & Impact:Conclusion: Induction of labor with either oxytocin or dinoprostone in women with uncomplicated term pregnancies had no adverse effects on umbilical artery blood gas parameters. (J Turkish-German Gynecol Assoc 2012; 13: 257-60)
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: To compare the effects of oxytocin and dinoprostone used in labor induction on fetal blood gas parameters. Material and Methods: This prospective randomized trial involved 108 women who completed 37 gestational weeks and who required labor induction prior to normal vaginal birth. Labor was induced in 57 women with an intravenous low dose oxytocin regimen and in 51 with intravaginal dinoprostone (PGE2). Following childbirth, umbilical artery blood gas was analyzed, with pH, pCO2, pO2, HCO3 and base excess (BE) compared in the two groups. Results: Mean age and obstetrical data (gravidity, parity, gestational weeks and birthweight) were similar in the two groups (p>0.05). All infants had 1 and 5 minute APGAR scores ≥7. Umbilical artery blood pH was similar in the oxytocin and dinoprostone groups (7.31±0.07 vs. 7.31±0.05, p=0.780), as were the other blood gas parameters (pCO2, pO2, base excess and HCO3; p>0.05 each). Conclusion: Induction of labor with either oxytocin or dinoprostone in women with uncomplicated term pregnancies had no adverse effects on umbilical artery blood gas parameters. (J Turkish-German Gynecol Assoc 2012; 13: 257-60)

Özet

Amaç: Bu çalışmada amacımız, doğum indüksiyonunda kullanılan iki metod olan oksitosin ve dinoprostonun fetal kan gazı parametreleri üzerine olan etkilerinin karşılaştırılmasıdır. Gereç ve Yöntemler: Bu prospektif randomize çalışmaya 37 gebelik haftasını doldurmuş ve doğum eylemi indüksiyonu uygulanan ve vajinal yoldan doğumu gerçekleşen 108 olgu alındı. Eylem indüksiyonu için 57 olguya intravenöz yolla oksitosin, 51 olguya ise intravajinal dinoproston (PG E2) uygulandı. Doğumu takiben umblikal arter kan gazı analizi yapıldı ve her iki indüksiyon metodu için bazı parametreler (pH, pCO2, pO2, HCO3 and baz açığı (BE)) incelendi. Bulgular: İki grup arasında ortalama yaş ve obstetrik değişkenler (gravida, parite, gebelik haftası ve doğum ağırlığı) benzer saptandı (p>0.05). Tüm olgularda 1. ve 5. dakika Apgar skoru ≥7 idi. Umbilikal arter kan pH değeri oksitosin grubunda 7.31±0.07 iken ; dinoproston grubunda 7.31±0.05 olarak izlendi (p=0.780). Diğer kan gazı parameterleri değerlendirildiğinde de (pCO2, pO2, baz açığı ve HCO3) iki grup arasında belirgin farklılık saptanmadı (p>0.05). Sonuç: Komplike olmayan term gebeliklerde doğum eylemi indüksiyonununda kullanılan iki metod olan oksitosin ve dinoprostonun fetal kan gazı parametreleri üzerine olumsuz etkisi yoktur.

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Cite This Article

KESKİN, H. L., ÜSTÜNER, I., KABACAOĞLU, G., YEĞİN, G., AVŞAR, A. F., İŞLEK, E. S. (2022). Doğum eylemi indüksiyonunda kullanılan intravajinal dinoproston ve oksitosin in umblikal arter kan gazı parametreleri üzerine etkilerinin karşılaştırılması. Journal of the Turkish-German Gynecological Association, Cilt: 13 - Sayı: 4, 257–260. https://ajindex.com/articles/567674

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References (5)

  1. Tenore JL. Methods for cervical ripening and induction of labor. Am Fam Physician 2003; 67: 2123-8. ACOG practice bulletin. Induction of labor. Number:10, November 1999 (Replaces technical bulletin No:217, December 1995). Obstet Gynecol Reproduction 1999; 94: 1-10. Mackenzie IZ. Induction of labour at the start of the new millen- nium. Reproduction 2006; 131: 989-98. [CrossRef] Mozurkewich EL, Chilimigras JL, Berman DR, Perni UC, Romero VC, King VJ, et al. Methods of induction of labour: a systematic review. BMC Pregnancy Childbirth 2011; 11: 84. [CrossRef] Akay NÖ, Hızlı D, Yılmaz SS, Yalvac S, Kandemir O. Comparison of low-dose oxytocin and dinoprostone for labor induction in post- term pregnancies: a randomized controlled prospective study. Gynecol Obstet Invest 2012; 73: 242-7. [CrossRef] Christensen FC, Tehranifar M, Gonzalez JL, Qualls CR, Rappaport VJ, Rayburn WF. Randomized trial of concurrent oxytocin with a sustained-release dinoprostone vaginal insert for labor induction at term. Am J Obstet Gynecol 2002; 186: 61-5. [CrossRef] Hadi H. Cervical ripening and labor induction: clinical guidelines. Clin Obstet Gynecol 2000; 43: 524-36. [CrossRef] Thorp JA, Dildy GA, Yeomans ER, Meyer BA, Parisi VM. Umbilical cord blood gas analysis at delivery. Am J Obstet Gynecol 1996; 175: 517-22. [CrossRef] Gordon A, Johnson JW. Value of umbilical blood acid-base studies in fetal assessment. J Reprod Med 1985; 30: 329-36.
  2. Dündar Ö, Tütüncü L, Ergür AR, Atasever B, Müngen E. Comparison of Intravaginal misoprostol, oxytocin infusion and intracervical dinoprostone, oxytocin infusion in postterm pregnancies for labor induction. Turkiye Klinikleri J Gynecol Obst 2008; 18: 231-6.
  3. Loghis C, Salamalekis E, Vitoratos N, Panayotopoulos N, Kassanos D. Umbilical cord blood gas analysis in augmented labour. J Obstet Gynaecol 1999; 19: 38-40. [CrossRef] Yılmaz B, Güngör T, Bilge U, Onen S, Ozaksit G, Sut N, et al. Randomized comparison of sustained-release dinoprostone vagi- nal insert versus oxytocin for cervical priming/labor induction in post-term pregnants with unfavorable cervix. Turkiye Klinikleri J Gynecol Obst 2008; 18: 237-42.
  4. Thorp JA, Boylan PC, Parisi VM, Heslin EP. Effects of high-dose oxytocin augmentation on umbilical cord blood gas values in pri- migravid women. Am J Obstet Gynecol 1988; 159: 670-5.
  5. Yogev Y, Ben-Haroush AB, Gilboa Y, Chen R, Kaplan B, Hod M. Induction of labor with vaginal prostaglandin E2. J Matern Fetal Neonatal Med 2003; 14: 30-4. [CrossRef]