AI Summary & Key Takeaways
AI InsightBecause survival is long at early stages and most of the patients are young, fertility sparing surgery could be safely suggested tothese patients.
📌 3 Key Takeaways
Abstract
Objective: We aimed to analyze the clinical characteristics and management of ten patients who were diagnosed with juvenile granulosa cellovarian tumor (JGCOT).Material and Methods: The records of 10 patients diagnosed with JGCOT between April 1995 and January 2014 in the Gynecological OncologyClinic of our institution were retrospectively evaluated.Results: The median age of the patients was 21.5 years (range; 13-36). Nine patients had stage IA disease and one had stage IC disease accord -ing to the International Federation of Gynecology and Obstetrics (FIGO) criteria. Five patients underwent pelvic and para-aortic lymph nodedissection. None of them had lymph node involvement. All but two patients underwent unilateral salpingo-oophorectomy. One of the other twopatients had cystectomy and the other had total abdominal hysterectomy and bilateral salpingo-oophorectomy. Three patients had adjuvanttherapy after surgery. Two of these patients took chemotherapy and the other took radiotherapy. Four of the five patients who desired pregnancyachieved five term pregnancies. The median follow-up time of the patients was 58 months (range; 3-113). No recurrence was observed in thefollow up period.Conclusion: JGCOT generally occurs during childhood. The primary management of JGCOT is through surgery. The role of adjuvant therapy iscontroversial. Because survival is long at early stages and most of the patients are young, fertility sparing surgery could be safely suggested tothese patients.