SavedAdd your journal

Journals / Cukurova Medical Journal / 2017 / Cilt: 42 - Sayı: 3

Relationship between vitamin D deficiency and musculoskeletal pain in postmenopausal women

Postmenapozal kadınlarda kas iskelet sistemi ağrılarının D vitamini eksikliği ile ilişkisi

Eda ÇELİK GÜZEL
Pages
470–476
Publication Date
2017-09-30
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Moreover, we believe that 25 (OH) D levels are more common in patients with lower levels of the lower extremities and that serum 25 (OH) D may play a role in determining the severity of musculoskeletal pain.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: The aim of this study was to investigate the effect of vitamin D deficiency on the appearance of musculoskeletal pain seen in postmenopausal women.Material and Methods: The study consisted of 130 patients in the postmenopausal period and 50 healthy volunteers.
📊
Key Findings & Data:Serum 25-hydroxyvitamin D (25 (OH) D), estradiol (E2) calcium, phosphorus, alkaline phosphatase (ALP) and parathormone (PTH) levels were evaluated.Results: The mean age of the subjects participating in the study was 51.03±4.22 and the control group was 48.27±5.47 years.
💡
Conclusion & Impact:Moreover, we believe that 25 (OH) D levels are more common in patients with lower levels of the lower extremities and that serum 25 (OH) D may play a role in determining the severity of musculoskeletal pain.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Postmenapozal dönem · D vitamini · Postmenopausal period

Abstract

Purpose: The aim of this study was to investigate the effect of vitamin D deficiency on the appearance of musculoskeletal pain seen in postmenopausal women.Material and Methods: The study consisted of 130 patients in the postmenopausal period and 50 healthy volunteers. Patients and control group were assessed with demographic information and visual analogue scale (VAS) and pain scores. Serum 25-hydroxyvitamin D (25 (OH) D), estradiol (E2) calcium, phosphorus, alkaline phosphatase (ALP) and parathormone (PTH) levels were evaluated.Results: The mean age of the subjects participating in the study was 51.03±4.22 and the control group was 48.27±5.47 years. Serum 25 (OH) D level was significantly lower in the patient group than in the control group. There was no difference between the two groups in calcium, phosphorus, ALP and PTH levels. The VAS pain score used to assess pain status was significantly higher in the patient group than in the control group (p<0.001). VAS pain scores in Postmenopausal patients were significantly higher in patients with vitamin D deficiency and inadequate than those with adequate vitamin D levels. In patients group serum 25(OH) D were negatively correlated with age, body mass index and VAS score and positively correlated with exercise and E2.Conclusion: The increase in pain intensity in postmenopausal patients is associated with a decrease in serum 25 (OH) D levels. Moreover, we believe that 25 (OH) D levels are more common in patients with lower levels of the lower extremities and that serum 25 (OH) D may play a role in determining the severity of musculoskeletal pain.

Özet

Amaç: Bu çalışmanın amacı postmenapozal dönemdeki kadınlarlarda görülen kas iskelet sistemi ağrılarının ortaya çıkmasında D vitamini eksikliğinin etkisini araştırmaktır

🔖

Cite This Article

GÜZEL, E. Ç. (2017). Relationship between vitamin D deficiency and musculoskeletal pain in postmenopausal women. Cukurova Medical Journal, Cilt: 42 - Sayı: 3, 470–476. https://ajindex.com/articles/56642

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. WHO Scientific Group on the Burden of Musculoskeletal Conditions at the Start of the New Millennium. The burden of musculoskeletal conditions at the start of the new millennium. World Health Organ Tech Rep Ser. 2003;919:1-218
  2. Woolf AD, Pfleger B. Burden of major musculoskeletal conditions. Bull World Health Organ. 2003;81:646-56
  3. Kadi F, Karlsson C, Larsson B, Eriksson J, Larval M, Billig H et al. The effects of physical activity and estrogen treatment on rat fast and slow skeletal muscles following ovariectomy. J Muscle Res Cell Motil. 2002;23:335-9
  4. Greising SM, Baltgalvis KA, Lowe DA, Warren GL. Hormone therapy and skeletal muscle strength: a meta-analysis. J Gerontol A Biol Sci Med Sci. 2009;64:1071–81
  5. Nedergaard A, Henriksen K, Karsdal MA, Christiansen C. Menoupause, estrogens and frailty. Gynecol Endocrinol. 2013;29:418-23
  6. Dennerstein L, Dudley EC, Hopper JL, Gurthrie JR, Burger HG. A prospective population-based study of menopausal symptoms. Obstet Gynecol. 2000; 96: 351–8
  7. Bischoff-Ferrari HA, Willett WC, Wong JB, Giovannucci E, Dietrich T, Dawson-Hughes B. Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. JAMA. 2005;293:2257–64
  8. Bischoff-Ferrari HA, Dietrich T, Orav EJ, Hu FB, Zhang Y, Karlson EW et al. Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged >or =60 y. Am J Clin Nutr. 2004;80:752-8
  9. Al Faraj S, Al Mutairi K. Vitamin D deficiency and chronic low back pain in Saudi Arabia. Spine. 2003;28:177-9
  10. Gloth FM 3rd, Lindsay JM, Zelesnick LB, Greenough WB 3rd. Can vitamin D deficiency produce an unusual pain syndrome? Arch Intern Med. 1991;15:1662-4
  11. Mascarenhas R, Mobarhan S. Hypovitaminosis D-induced pain. Nutr Rev. 2004;62:354-9
  12. Plotnikoff GA, Quigley JM. Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain. Mayo Clin Proc. 2003;78:1463-70
  13. Gerdhem P, Ringsberg KA, Obrant KJ, Akesson K. Association between 25-hydroxy vitamin D levels, physical activity, muscle strength and fractures in the prospective population-based OPRA Study of Elderly Women. Osteoporos Int. 2005;16:1425-31
  14. Lips P, Hosking D, Lippuner K, Norquist JM, Wehren L, Maalouf G et al. The prevalence of vitamin D inadequacy amongst women with osteoporosis. an international epidemiological investigation. J Intern Med. 2006;260:245-54
  15. Heaht IKM, El