Journals / Cukurova Medical Journal / 2019 / Cilt: 44 - Sayı: 3

The relationship between metabolic syndrome and vitamin D levels in patients with schizophrenia

Şizofreni tanılı hastalarda metabolik sendrom ve D vitamini düzeyleri ilişkisi

Pages
1110–1117
Publication Date
2019-09-30
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: It has been shown that vitamin D blood level should be taken into account in the factors that increase the risk of metabolic syndrome..

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: The aim of this study was to determine the relationship between vitamin D levels, Positive and Negative Syndrome Scale scores, the use of antipsychotics and sociodemographic data in metabolic syndrome in patients with schizophrenia.Materials and Methods: A total of 119 patients with schizophrenia who were treated at inpatients clinics of Çukurova University Faculty of Medicine Department of Psychiatry were included in this retrospective study.
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Key Findings & Data:Thirtyone of 119 patients with schizophrenia were diagnosed with metabolic syndrome.
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Conclusion & Impact:Conclusion: It has been shown that vitamin D blood level should be taken into account in the factors that increase the risk of metabolic syndrome..
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Metabolik sendrom · D vitamini · psikotik bozukluk

Abstract

Purpose: The aim of this study was to determine the relationship between vitamin D levels, Positive and Negative Syndrome Scale scores, the use of antipsychotics and sociodemographic data in metabolic syndrome in patients with schizophrenia.Materials and Methods: A total of 119 patients with schizophrenia who were treated at inpatients clinics of Çukurova University Faculty of Medicine Department of Psychiatry were included in this retrospective study. Thirtyone of 119 patients with schizophrenia were diagnosed with metabolic syndrome. Sociodemographic data, duration of disorder, number of hospitalizations, Positive and Negative Syndrome Scale scores, vitamin D blood levels, HDL, triglyceride, glucose, HBa1c, arterial blood pressure, waist circumference, body mass index were measured.. Results: Of the patients included in the study, 63 were female and 56 were male. Vitamin D levels were lower in 63 patients. Significant differences were found in HDL, arterial blood pressure, fasting blood glucose, triglyceride, waist circumference, body mass index values among those with and without metabolic syndrome. These values are not included in the logistic regression analysis because they are metabolic syndrome diagnostic criteria for the National Cholesterol Education Program Adult Treatment Panel III. Simple linear regression and logistic regression analysis showed that the disease year and patient ages were significantly higher and vitamin D levels were significantly lower in the metabolic syndrome group. Conclusion: It has been shown that vitamin D blood level should be taken into account in the factors that increase the risk of metabolic syndrome..

Özet

Amaç: Bu çalışmada şizofreni tanılı hastalarda D vitamini, Pozitif ve Negatif Sendrom Ölçeği skorları, antipsikotik kullanımı ve sosyodemografik verilerin metabolik sendrom ile ilişkisinin gösterilmesi amaçlanmıştır.Gereç ve Yöntem: Retrospektif dosya tarama esasına bağlı bu çalışmaya Çukurova Üniversitesi Tıp Fakültesi Ruh Sağlığı ve Hastalıkları Anabilim Dalı yataklı servisinde sağaltım görmüş 31’inde metabolik sendrom tanısı olan 119 şizofreni tanılı hasta dahil edilmiştir. Hastaların sosyodemografik verileri, hastalık yılı, yatış sayısı, Pozitif ve Negatif Sendrom Ölçeği skorları, vitamin D kan düzeyleri, HDL, trigliserit, glukoz, HBa1c, arteriyel kan basıncı değerleri, bel çevresi, vücut kitle indeksi ölçümleri incelenmiştir. Bulgular: Çalışmaya dahil edilen hastaların 63’ü kadın, 56’sı erkektir. Hastaların 63’ünde vitamin D düzeyi düşüklüğü saptanmıştır. MS tanısı olanlar ve olmayanları arasında HDL, arteriyel kan basıncı, açlık kan glukozu, trigliserit, bel çevresi, vücut kitle indeksi değerlerinin analizinde anlamlı farklılık saptanmıştır. Bu değerler National Cholesterol Education Programme Adult Treatment Panel III metabolik sendrom tanı kriterleri olduğu için lojistik regresyon analizine dahil edilmemiştir. Basit lineer regresyon ve lojistik regresyon analizi ile metabolik sendrom tanısı olan grupta olmayanlara göre hastalık yılı ve hasta yaşları anlamlı olarak yüksek, D vitamini düzeyleri anlamlı olarak düşük saptanmıştır.Sonuç: Bu çalışmada metabolik sendrom riskini arttıran faktörlerden değiştirilebilir olan vitamin D kan düzeyine dikkat edilmesi gerektiği gösterilmiştir.

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Cite This Article

DEMİRKOL, M. E., TAMAM, L., ÇAKMAK, S., YEŞİLOĞLU, C. (2019). The relationship between metabolic syndrome and vitamin D levels in patients with schizophrenia. Cukurova Medical Journal, Cilt: 44 - Sayı: 3, 1110–1117. https://ajindex.com/articles/56410

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