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Journals / Journal of Clinical Research in Pediatric Endocrinology / 2022 / Cilt: 14 - Sayı: 2

Low Complement C1q/TNF-related Protein-13 Levels are Associated with Childhood Obesity But not Binge Eating Disorder

Serkan TURAN
Ahu PAKETÇİ
İbrahim Mert ERBAŞ
Ali Rıza ŞİŞMAN
Ece BÖBER
Korcan DEMİR
Ayhan ABACI
Pages
179–187
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Serum adiponectin and CTRP-13 levels were significantly lower in children with obesity than controls (7.1 vs 20.1 μg/mL, p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: C1q/tumor necrosis factor-related proteins (CTRPs) are recently described members of the adipokine family.
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Key Findings & Data:CTRP-13, a new member of this family, has been shown to increase insulin sensitivity and had an anorexigenic effect on food intake in experimental studies.
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Conclusion & Impact:Serum adiponectin and CTRP-13 levels were significantly lower in children with obesity than controls (7.1 vs 20.1 μg/mL, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: C1q/tumor necrosis factor-related proteins (CTRPs) are recently described members of the adipokine family. CTRP-13, a new member of this family, has been shown to increase insulin sensitivity and had an anorexigenic effect on food intake in experimental studies. The aim was to investigate serum CTRP-13 levels in children with obesity, and its relationship with other adipokines, metabolic parameters, or binge eating disorder (BED). Methods: A cross-sectional study was conducted with 105 pubertal children attending a single center. Clinical (metabolic syndrome, BED) and biochemical (glucose, insulin, lipids, leptin, adiponectin, CTRP-13 levels) parameters were assessed. Results: Sixty children with obesity [24 males (40%); median age 14.7 (13.0-16.4) years] and 45 healthy controls [15 males (33.3%); median age 15.2 (14.1-16.5) years] were included. Serum adiponectin and CTRP-13 levels were significantly lower in children with obesity than controls (7.1 vs 20.1 μg/mL, p

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Cite This Article

TURAN, S., PAKETÇİ, A., ERBAŞ, İ. M., ŞİŞMAN, A. R., BÖBER, E., DEMİR, K., ABACI, A. (2022). Low Complement C1q/TNF-related Protein-13 Levels are Associated with Childhood Obesity But not Binge Eating Disorder. Journal of Clinical Research in Pediatric Endocrinology, Cilt: 14 - Sayı: 2, 179–187. https://ajindex.com/articles/562198

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