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Journals / Journal of Clinical and Experimental Investigations / 2012 / Cilt: 3 - Sayı: 1

Comparison of the efficacy of dexmedetomidine and esmolol in the treatment of increased hemodynamic response during the recovery period

Deksmedetomidin ve esmololün derlenme döneminde oluşan artmış hemodinamik yanıt tedavisindeki etkinliklerinin karşılaştırılması

Hülya GÜNAY
Belgin YAVAŞCAOĞLU
Gürkan TÜRKER
Elif MOĞOL BAŞAĞAN
Filiz AHUN
Ayşe Neslihan BEBEK
Tuba YENİAYDOĞMUŞ
Fatma Nur KAYA
Pages
53–60
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: After drug, HR reductions were significant at all periods in group Dexmedetomidine (Z2-Z10: p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Our aim was to compare effectiveness of esmolol and dexmedetomidine in the treatment of increased hemodynamic response during anesthesia recovery period.
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Key Findings & Data:Materials and methods: 60 ASA I-II patients whom scheduled for elective surgery with endotracheal intubation were randomized before extubation according to their hemodynamic parameters that were increased 20% of their baseline values in order to receive 1mg/kg esmolol (Group Esmolol, n= 30) or 0.5 μg/kg dexmedetomidine (Group Dexmedetomidine, n= 30).
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Conclusion & Impact:Results: After drug, HR reductions were significant at all periods in group Dexmedetomidine (Z2-Z10: p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Our aim was to compare effectiveness of esmolol and dexmedetomidine in the treatment of increased hemodynamic response during anesthesia recovery period. Materials and methods: 60 ASA I-II patients whom scheduled for elective surgery with endotracheal intubation were randomized before extubation according to their hemodynamic parameters that were increased 20% of their baseline values in order to receive 1mg/kg esmolol (Group Esmolol, n= 30) or 0.5 μg/kg dexmedetomidine (Group Dexmedetomidine, n= 30). Heart rate (HR), systolic and diastolic blood pressures (SBP,DBP), peripheral oxygen saturation (SpO2), end tidal carbon dioxide (ETCO2) values, extubation time, recovery time were recorded. The duration till having pain requiring analgesic was recorded and cognitive functions were evaluated with short memory orientation concentration test at 20th and 50th minutes. Results: After drug, HR reductions were significant at all periods in group Dexmedetomidine (Z2-Z10: p

Özet

Amaç: Bu çalışmada amacımız, anestezinin derlenme döneminde oluşan artmış hemodinamik yanıt tedavisinde esmolol ve deksmedetomidinin etkinliklerinin karşılaştırılmasıdır. Gereç ve yöntem: Endotrakeal entübasyon uygulanarak elektif girişim planlanan 60 ASA I-II hasta, ekstübasyon öncesinde hemodinamik parametrelerde kontrol değerine göre %20’den fazla artış olduğunda, 1 mg/kg esmolol (Grup Esmolol, n=30) ya da 0.5 μg/kg deksmedetomidin (Grup Deksmedetomidin, n=30) kullanılmasına göre randomize olarak ayrıldı. Kalp atım hızı (KAH), sistolik ve diyastolik kan basıncı (SKB ve DKB), periferik oksijen satürasyonu (SpO2), soluk sonu karbondioksit (ETCO2) değerleri, ekstübasyon süresi, derlenme süresi kaydedildi. Analjezik gerektiren ağrının başlama süresi kaydedildi, kognitif fonksiyonlar kısa hafıza oryantasyon konsantrasyon testi ile 20. ve 50.dk’da değerlendirildi. Bulgular: İlacının verilmesi sonrası tüm dönemlerde KAH’deki düşme Grup Deksmedetomidin’de daha belirgindi (Z2-Z10:p

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Cite This Article

GÜNAY, H., YAVAŞCAOĞLU, B., TÜRKER, G., BAŞAĞAN, E. M., AHUN, F., BEBEK, A. N., YENİAYDOĞMUŞ, T., KAYA, F. N. (2022). Comparison of the efficacy of dexmedetomidine and esmolol in the treatment of increased hemodynamic response during the recovery period. Journal of Clinical and Experimental Investigations, Cilt: 3 - Sayı: 1, 53–60. https://ajindex.com/articles/562152

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