Journals / Journal of Clinical and Experimental Investigations / 2012 / Cilt: 3 - Sayı: 4

Mortality and morbidity analysis in neonates supported by invasive mechanical ventilation

İnvaziv mekanik ventilatör desteği alan yenidoğanlarda morbidite ve mortalite analizi

Pages
483–492
Publication Date
2022-10-18
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Neonates born at 1000 gram (p

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Objective & Hypothesis:Objectives: To evaluate mortality, morbidity, and invasive mechanical ventilation complications in mechanically ventilated neonates in a tertiary care hospital, Istanbul, Turkey.
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Key Findings & Data:Materials and methods: The neonates followed on invasive mechanical ventilation from January 2008 to December 2009 were included in the study.
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Conclusion & Impact:Neonates born at 1000 gram (p
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: To evaluate mortality, morbidity, and invasive mechanical ventilation complications in mechanically ventilated neonates in a tertiary care hospital, Istanbul, Turkey. Materials and methods: The neonates followed on invasive mechanical ventilation from January 2008 to December 2009 were included in the study. A chart is formed for each patient to record patient delivery room and clinical data prospectively. Results: The study population consisted of 236 neonates. Eighty-five percent were born at ≤37 completed weeks ofgestation (n=201). Fifty-two percent (n=123) were males. The mean gestational age was 31.9±5 weeks. The mean birthweight was 1870.8±921.8 g. Antenatal steroid rate was 13.3% (n=20) in 150 cases born at ≤34 weeks of gestation. Respiratory distress syndrome (n=100, 42,3%), perinatal depression and asphyxia (n=51, 21,6%), and sepsis (n=47, 19.9%) were the commonest indications. Mechanical ventilation related complications (nosocomial infection (n=57), pulmonary hemorrhage (n=30), pneumonia (n=10), pneumothorax (n=9), and atelectasis (n=4)) developed in 33.5% of neonates (n=79). Broncho- pulmonary dysplasia was 9.3%, intracranial hemorrhage (≥grade 3) 8.47%, periventricular leukomalacia 5.93%,necrotizing enterocolitis (>stage 2) 0.42%, and retinopathy of prematurity (>stage 2) 2.96%. Mortality rate was 30.17%. Neonates born at 1000 gram (p

Özet

Amaç: Bu çalışmada invazif mekanik ventilasyon tedavisialan yenidoğanların mortalite ve morbidite analizini yapmak, mekanik ventilasyon komplikasyonlarını irdelemekamaçlandı.Gereç ve yöntem: Hastanemiz Yenidoğan Yoğun BakımÜnitesi’nde 1 Ocak 2008-31 Aralık 2009 tarihleri arasında invazif mekanik ventilasyon tedavisi alan 236 olgu çalış-maya dahil edildi. Vakaların prospektif olarak formlara kaydedilen doğumhane ve klinik verileri değerlendirildi.Bulgular: Olgularımızın 123’ü erkekti, 201’i ≤37 gestas- yon haftasında doğmuştu. Doğum ağırlıkları ortalaması 1870,8±921,8 gramdı. Ortalama gestasyon haftası 31,9±5 idi. Gestasyon haftası≤34 olan 150 olgunun %13,3‘üne(n=20) antenatal steroid uygulanmıştı. Vakaların %84,7’si hastanemizde doğurtulmuştu. Ortalama hastane yatış süresi 26,28±26,96 gündü. Mekanik ventilasyon endikas- yonlarının başında respiratuar distres sendromu (n=100, %42,3), perinatal depresyon ve asfiksi (n=51, %21,6) ve sepsis (n=47, %19,9) gelmekteydi. Hastaların %33,5‘inde (n=79) ventilatör komplikasyonu saptandı. Elliyedi olgudanozokomiyal enfeksiyon, 30 olguda pulmoner hemora-ji, 10 olguda pnömoni, 9 olguda pnömotoraks, 4 olguda ise atelektazi gelişmişti. Bronkopulmoner displazi %9,3olguda, intrakranyal kanama (≥3. derece) %8,47 olgu- da, periventriküler lökomalazi %5,93 olguda, nekrotizanenterokolit (>evre 2) %0,42 olguda, prematüre retino-patisi (>evre 2) %2,96 olguda saptandı. Mortalite oranı %30,17’di. Mortalite oranı, gestasyon haftası 28 olan bebeklere kıyas-la ve doğum ağırlığı ≤1000 gr olan bebeklerde, doğum ağırlığı >1000 gr olan bebeklere kıyasla anlamlı yüksekti (sırasıyla, p

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Cite This Article

HATİPOĞLU, S., SALİHOĞLU, Ö., AKYOL, B., TAN, İ., Kılıç, B. A. (2022). Mortality and morbidity analysis in neonates supported by invasive mechanical ventilation. Journal of Clinical and Experimental Investigations, Cilt: 3 - Sayı: 4, 483–492. https://ajindex.com/articles/561910

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