Journals / Journal of Ankara Medical School / 1997 / Cilt: 19 - Sayı: 3

COPD , platelet functions and N-acetyl cysteine

Pages
121–125
Publication Date
2022-10-17
DOI
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In our study it was observed that N-Acetyl Cysteine treatment decreased the platelet aggregation response in¬duced by collagen significantly (p

📌 3 Key Takeaways

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Objective & Hypothesis:In our department previously it has been determined that in COPD (chronic obstructive pulmonary disease) pa¬tients-there is oxidant stress, tendency for hypercoagulability and increase in platelet functions.
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Key Findings & Data:In the presented study, it was aimed to determine the effect of antioxidant defense supportive treatment on pla¬telet functions. 15 COPD patients were treated by 600 mg/day (3x200 mg) N-Acetyl Cysteine, "ASIST" (Bilim ilaç San. ve Tic.
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Conclusion & Impact:In our study it was observed that N-Acetyl Cysteine treatment decreased the platelet aggregation response in¬duced by collagen significantly (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In our department previously it has been determined that in COPD (chronic obstructive pulmonary disease) pa¬tients-there is oxidant stress, tendency for hypercoagulability and increase in platelet functions. In the presented study, it was aimed to determine the effect of antioxidant defense supportive treatment on pla¬telet functions. 15 COPD patients were treated by 600 mg/day (3x200 mg) N-Acetyl Cysteine, "ASIST" (Bilim ilaç San. ve Tic. A.Ş) for 3 months and platelet aggregation responses in whole blood to ADP and collagen were exami¬ned before and after treatment. In our study it was observed that N-Acetyl Cysteine treatment decreased the platelet aggregation response in¬duced by collagen significantly (p

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Cite This Article

YAVUZER, S., OCAKÇIOĞLU, B., KAYABIYIKLIOĞLU, G., AKKOCA, Ö. (2022). COPD , platelet functions and N-acetyl cysteine. Journal of Ankara Medical School, Cilt: 19 - Sayı: 3, 121–125. https://ajindex.com/articles/560180

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