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Journals / Joint diseases and related surgery / 2021 / Cilt: 32 - Sayı: 1

Impact of radial extracorporeal shock wave therapy in post-laminectomy epidural fibrosis in a rat model

Bahtiyar HABERAL
Ekin KAYA ŞİMŞEK
Fikret ŞAHİNTÜRK
Koray AKPINAR
Duygu TÜRKBEY ŞİMŞEK
Pages
162–169
Publication Date
2022-10-19
DOI
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⚡ TL;DR(Too Long; Didn't Read)

There was no statistically significant difference between the groups in terms of acute and chronic inflammation response and vascular proliferation.Conclusion: The rESWT application immediately after surgery is effective in preventing epidural fibrosis after laminectomy in rats.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: This study aims to investigate the effect of radial extracorporeal shock wave therapy (rESWT) treatment in the prevention of epidural fibrosis after laminectomy in rats.Materialsandmethods:Eighteen 16-month-old male Sprague-Dawley rats weighing 300 g were used in this experimental study between November 2019 and February 2020.
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Key Findings & Data:The rats were randomly divided into two groups as the control group (L3-L4 total laminectomy without any treatment) and the study group (L3-L4 total laminectomy plus rESWT).
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Conclusion & Impact:There was no statistically significant difference between the groups in terms of acute and chronic inflammation response and vascular proliferation.Conclusion: The rESWT application immediately after surgery is effective in preventing epidural fibrosis after laminectomy in rats.
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: This study aims to investigate the effect of radial extracorporeal shock wave therapy (rESWT) treatment in the prevention of epidural fibrosis after laminectomy in rats.Materialsandmethods:Eighteen 16-month-old male Sprague-Dawley rats weighing 300 g were used in this experimental study between November 2019 and February 2020. The rats were randomly divided into two groups as the control group (L3-L4 total laminectomy without any treatment) and the study group (L3-L4 total laminectomy plus rESWT). The rats were sacrificed at the postoperative sixth week and the lumbar spine was excised en bloc, fixed, and decalcified. Sections were stained with hematoxylin-eosin to evaluate epidural fibrosis, acute inflammation, chronic inflammation, and vascular proliferation.Results: The median value and standard deviations were obtained based on histological examinations. Accordingly, epidural fibrosis decreased significantly in the study group compared to the control group. There was no statistically significant difference between the groups in terms of acute and chronic inflammation response and vascular proliferation.Conclusion: The rESWT application immediately after surgery is effective in preventing epidural fibrosis after laminectomy in rats.

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Cite This Article

HABERAL, B., ŞİMŞEK, E. K., ŞAHİNTÜRK, F., AKPINAR, K., ŞİMŞEK, D. T. (2022). Impact of radial extracorporeal shock wave therapy in post-laminectomy epidural fibrosis in a rat model. Joint diseases and related surgery, Cilt: 32 - Sayı: 1, 162–169. https://ajindex.com/articles/559211

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References (13)

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