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Journals / Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi / 2018 / Cilt: 15 - Sayı: 4

To Which Patients Should Intrauterine HCG Injection Be Applied In In Vitro Fertilization?

ntrauterin HCG Enjeksiyonu IVF' te Hangi Hastalara Uygulanmalıdır?

Necati ÖZÇİMEN
Ali Sami GÜRBÜZ
Emel Ebru ÖZÇİMEN
Pages
159–163
Publication Date
2022-10-18
DOI
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⚡ TL;DR(Too Long; Didn't Read)

IntrauterinehCG injection was performed before ET in the study groups.Results: The pregnancy, clinical pregnancy and implantation rates weresignificantly increased in the intrauterine hCG injected patients with thirdor more IVF cycles (p= 0.03, p= 0.02, p= 0.02) respectively.Conclusion: The intrauterine hCG injection improved the pregnancy ratesin the patient with recurrent IVF failures.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: To investigate the impact of the intrauterine injection of hCG before embryo transfer in in vitro fertilization (IVF) according to number oftransfer.Material And Methods: One hundred and sixty-eight (168) patients wereincluded to the study group; 274 patients were included to the controlgroup.
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Key Findings & Data:The patients were divided into 2 study and 2 control groups.Group 1:Study group patients in the first and the second IVF cycles.(N=126)Group 2:Control group patients in the first and the second IVF cycles.(N=189)Group 3:Study group patients in the third or more IVF cycles. (N=42)Group 4:Control group patients in the third or more IVF cycles. (N=85)Fresh IVF-embryo transfer (ET) was performed to all patients.
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Conclusion & Impact:IntrauterinehCG injection was performed before ET in the study groups.Results: The pregnancy, clinical pregnancy and implantation rates weresignificantly increased in the intrauterine hCG injected patients with thirdor more IVF cycles (p= 0.03, p= 0.02, p= 0.02) respectively.Conclusion: The intrauterine hCG injection improved the pregnancy ratesin the patient with recurrent IVF failures.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: To investigate the impact of the intrauterine injection of hCG before embryo transfer in in vitro fertilization (IVF) according to number oftransfer.Material And Methods: One hundred and sixty-eight (168) patients wereincluded to the study group; 274 patients were included to the controlgroup. The patients were divided into 2 study and 2 control groups.Group 1:Study group patients in the first and the second IVF cycles.(N=126)Group 2:Control group patients in the first and the second IVF cycles.(N=189)Group 3:Study group patients in the third or more IVF cycles. (N=42)Group 4:Control group patients in the third or more IVF cycles. (N=85)Fresh IVF-embryo transfer (ET) was performed to all patients. IntrauterinehCG injection was performed before ET in the study groups.Results: The pregnancy, clinical pregnancy and implantation rates weresignificantly increased in the intrauterine hCG injected patients with thirdor more IVF cycles (p= 0.03, p= 0.02, p= 0.02) respectively.Conclusion: The intrauterine hCG injection improved the pregnancy ratesin the patient with recurrent IVF failures.

Özet

Amaç: İn vitro fertilizasyon (IVF) tedavisinde embryo transferinden önce yapılan intrauterin human chorionic gonadothropin enjeksiyonlarının etkisinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntemler: Yüz atmış sekiz hasta çalışma grubuna alındı. 274 hasta ise kontrol grubuna dahil edildi. Hasta grupları kendi içinde de ikiye ayrıldı. Grup 1: Birinci ve ikinci IVF denemesi olan çalışma grubu hastaları (N:126) Grup 2: Birinci ve ikinci IVF denemesi olan control grubu hastaları (N:189) Grup 3: Üç veya daha fazla IVF denemesi olan çalışma grubu hastaları (N:42) Grup 4: Üç veya daha fazla IVF denemesi olan control grubu hastaları. (N:85). Tüm hastalara taze embryo transferi (ET) yapıldı. Çalışma grubuna ET öncesi intrauterine hcg enjeksiyonu uygulandı. Bulgular: Üç veya daha fazla sayıda IVF uygulaması yapılmış hastalarda gebelik , klinik gebelik ve implantasyon oranları intrauterine hCG enjekte edilenlerde belirgin düzeyde yüksek çıkmıştır. (p=0,03, p=0,02, p=0,02 sırasıyla) Sonuç: Intrauterin hCG enjeksiyonu tekrarlayan IVF başarısızlığı olan hastalarda gebelik oranlarını iyileştirmektedir.

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Cite This Article

ÖZÇİMEN, N., GÜRBÜZ, A. S., ÖZÇİMEN, E. E. (2022). To Which Patients Should Intrauterine HCG Injection Be Applied In In Vitro Fertilization?. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi, Cilt: 15 - Sayı: 4, 159–163. https://ajindex.com/articles/558691

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