An Essential Point in Hyperemesis Gravidarum: Vitamin D and Thyroid Functions

Objective & Hypothesis:Objective: Hyperemesis gravidarum is a condition that causes vomiting more than three times a day, liquid- electrolite, acid- base imbalance, malnutrition and weight loss with ketonuria.

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Key Findings & Data:Material and Methods: We inculeded to our study 132 pregnants that has hyperemesis gravidarum and 233 healty pregnants that has similar characteristics with study group who applied to Samsun Obstetrics and Gynecology Hospital and Health Sciences University Samsun Educational and Research Hospital Obstetrics and Gynecology Department in between January 2017 and July 2018 dates.

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Conclusion & Impact:Results: According to our study results ; vitamin D levels of hyperemesis gravidarum patients was found significantly lower(p=0.001; p

🔬Design:Research Article

📍Scope:2017 Verileri

⚙️Variables:Domain Parameters

Abstract

Objective: Hyperemesis gravidarum is a condition that causes vomiting more than three times a day, liquid- electrolite, acid- base imbalance, malnutrition and weight loss with ketonuria. Although there are various underlying reasons , it is considered that alterations in thyroid fonctions and vitamin D plays role in the etiology. So we aimed to evaluate the effects of vitamin D on ımmune mechanisms of hyperemesis and thyroid fonctions. Material and Methods: We inculeded to our study 132 pregnants that has hyperemesis gravidarum and 233 healty pregnants that has similar characteristics with study group who applied to Samsun Obstetrics and Gynecology Hospital and Health Sciences University Samsun Educational and Research Hospital Obstetrics and Gynecology Department in between January 2017 and July 2018 dates. TSH, T3,T4 and vitamin D levels of these pregnants was evaluated restrospectively. Results: According to our study results ; vitamin D levels of hyperemesis gravidarum patients was found significantly lower(p=0.001; p

Özet

Amaç: Hiperemezis gravidarum ketonüri ile birlikte günden 3 defadanfazla kusma, sıvı elektrolit, asit-baz dengesizliği, beslenme bozukluğu vekilo kaybına neden olan bir durumdur. Altta yatan çeşitli sebepleri olmakla birlikte tiroid fonksiyonlarındaki değişim ve vitamin D’nin de etiyolojiderol oynadığı düşünülmektedir. Biz de çalışmamızda hiperemezisteki immün mekanizmalar üzerindeki D vitaminin rolünü ve tiroid fonksiyonlarının etkisini incelemeyi amaçladık.Gereç ve Yöntem: Çalışmamıza 2017 Ocak -2018 Temmuz ayları arasında Samsun Kadın Hastalıkları ve Doğum Hastanesi ve Sağlık BilimleriÜniversitesi Samsun Eğitim ve Araştırma Hastanesi Kadın Hastalıklarıve Doğum Bölümü’ne başvuran hiperemezis gravidarum olan 132 vevaka grubuyla benzer özelliklere sahip sağlıklı 233 gebe dahil edildi. Bugebelerin TSH,T3,T4 ve vitamin D düzeyleri retrospektif olarak değerlendirildi.Bulgular: Çalışma sonuçlarımıza göre D vitamini seviyeleri hiperemezis gravidarum olan hastalarda anlamlı olarak daha düşük saptanmıştır (p=0.001; p

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Cite This Article

TÜRE, E., GÜVEY, H., YAZICIOĞLU, B., ÇELIK, S., ÇALIŞKAN, C. S., YAŞAR, B., ULUBAŞOĞLU, H. (2022). An Essential Point in Hyperemesis Gravidarum: Vitamin D and Thyroid Functions. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi, Cilt: 17 - Sayı: 2, 331–334. https://ajindex.com/articles/558610

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