Journals / İzmir Göğüs Hastanesi Dergisi / 2020 / Cilt: 34 - Sayı: 1

Are Patients With Tuberculous Pleurisy With Low ADA Levels Different from Those With High ADA Levels?

Düşük ADA Düzeyi Olan Tüberküloz Plörezili Hastalar, Yüksek ADA Düzeyi Olanlardan Farklı mıdır?

Pages
20–26
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Anystatistically significant differences were not detected among the patients who had low and high pleural fluid ADA levels in terms of age, gender, clinical symptoms, amounts ofpleural fluid (low, median, massive), its characteristics (free, loculated, empyema), and its cytology (lymphocytic, neutrop-hilic, mixed).However, it was determined that parenchymal involvement was higher at a statis-tically significant level in those who had increasedpleural fluid ADA values (≥40 IU/L), and those who had low ADA values of the pleural thickening (

📌 3 Key Takeaways

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Objective & Hypothesis:Objective:We aimed to compare the patients with low andhigh ADA levels in terms of their clinical, radiological and cytopathological features.Method:Tuberculous pleural effusion (TPE) patients who underwent thoracentesis were retros-pectively reviewed.
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Key Findings & Data:The pleural fluid profiles were compared between patients with low and high ADA levels.Results:A total of 138 patients consisting of 43 women and 95 men, who were diagnosed with tuberculous pleurisy with a mean age of 36, were included in the present study.
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Conclusion & Impact:Anystatistically significant differences were not detected among the patients who had low and high pleural fluid ADA levels in terms of age, gender, clinical symptoms, amounts ofpleural fluid (low, median, massive), its characteristics (free, loculated, empyema), and its cytology (lymphocytic, neutrop-hilic, mixed).However, it was determined that parenchymal involvement was higher at a statis-tically significant level in those who had increasedpleural fluid ADA values (≥40 IU/L), and those who had low ADA values of the pleural thickening (
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective:We aimed to compare the patients with low andhigh ADA levels in terms of their clinical, radiological and cytopathological features.Method:Tuberculous pleural effusion (TPE) patients who underwent thoracentesis were retros-pectively reviewed. The pleural fluid profiles were compared between patients with low and high ADA levels.Results:A total of 138 patients consisting of 43 women and 95 men, who were diagnosed with tuberculous pleurisy with a mean age of 36, were included in the present study. Anystatistically significant differences were not detected among the patients who had low and high pleural fluid ADA levels in terms of age, gender, clinical symptoms, amounts ofpleural fluid (low, median, massive), its characteristics (free, loculated, empyema), and its cytology (lymphocytic, neutrop-hilic, mixed).However, it was determined that parenchymal involvement was higher at a statis-tically significant level in those who had increasedpleural fluid ADA values (≥40 IU/L), and those who had low ADA values of the pleural thickening (

Özet

Amaç:Bu çalışmada düşük ADA düzeyi olan TPE’lu hastalar ile yüksek ADA düzeyine sahip olan hastaları klinik, radyolojik, sitopatolojik özellikleri yönünden karşılaştırılması amaçlandı.Yöntem: Torasentez yapılan tüberküloz plevral efüzyon (TPE) hastaları retrospektif olarak incelen-di. Plevral sıvı profilleri düşük ADA seviyeleri ile yüksek ADA seviyeleri arasında karşılaştırıldı.Bulgular:Çalışmaya 95 erkek, 43 kadın ve median yaş ortalaması 36 olan tüberküloz plörezi tanısı konan 138 hasta dahil edildi. Hastaların çeşitli klinik, sitopatolojik, mikrobiyolojik ve rad-yolojik özellikleri tabloda gösterilmiştir. Plevral sıvı ADA değeri düşük ve yüksek olan hastalar arasında yaş, cinsiyet, klinik, plevral sıvı miktarı (az, orta, masif), karakteri (serbest, loküle, ampi-yem) ve sitolojisi (lenfosittik, nötrofilik, mix) yönünden istatistiksel olarak anlamlı fark saptanma-dı. Ancak plevral sıvı ADA değeri (≥ 40 IU/L) yüksek olanlarda parenkimal tutulumun, plevral kalınlaşmanın ADA değeri (< 40 IU/L) düşük olanlara göre istatistiksel olarak anlamlı düzeyde daha fazla olduğu bulundu (sırasıyla p: 0,011, 0,016).Sonuç:Tüberküloz plörezili hastaların klinik, radyolojik ve histopatolojik bulgularının ADA düze-yine göre farklılık göstermeyebileceği akılda tutulmalıdır.

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Cite This Article

ALICI, İ. O., ANAV, C., YAVUZ, M. Y., BÜYÜKŞİRİN, M., GÜLDAVAL, F. (2022). Are Patients With Tuberculous Pleurisy With Low ADA Levels Different from Those With High ADA Levels?. İzmir Göğüs Hastanesi Dergisi, Cilt: 34 - Sayı: 1, 20–26. https://ajindex.com/articles/557839

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