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Journals / İzmir Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2022 / Cilt: 26 - Sayı: 1

MONOCYTE / HDL-CHOLESTEROL AND NEUTROPHIL / HDL-CHOLESTEROL RATIOS IN THE DIABETIC PROCESS

DİYABETİK SÜREÇTE MONOSİT/HDL-KOLESTEROL VE NÖTROFİL/HDL-KOLESTEROL ORANLARI

Esin AVŞAR
Mustafa AYDEMİR
Hasan SÖZEL
Mustafa Serkan ALEMDAR
Pages
19–29
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

HbA1c, creatinine, triglyceride, glucose and NHR values increased, while estimated glomerular filtration rate (eGFR) and high density lipoprotein cholesterol (HDL-C) values decreased as the patients progressed from the NGT group to the T2DM group(p

📌 3 Key Takeaways

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Objective & Hypothesis:inexpensive markers of subclinical inflammation for chronic diseases.
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Key Findings & Data:Material and Method: 1112 participants (male/female=392/720) were divided into five groups according to OGTT results: group 1 = normal glucose tolerance (NGT), group 2 = impaired fasting glucose (IFG), group 3 = isolated impaired glucose tolerance (IGT), group 4 = both IFG and IGT, and group 5 = type 2 diabetes mellitus (T2DM).
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Conclusion & Impact:HbA1c, creatinine, triglyceride, glucose and NHR values increased, while estimated glomerular filtration rate (eGFR) and high density lipoprotein cholesterol (HDL-C) values decreased as the patients progressed from the NGT group to the T2DM group(p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

inexpensive markers of subclinical inflammation for chronic diseases. This study aimed to evaluate MHR and NHR in participants with different glucose tolerances. Material and Method: 1112 participants (male/female=392/720) were divided into five groups according to OGTT results: group 1 = normal glucose tolerance (NGT), group 2 = impaired fasting glucose (IFG), group 3 = isolated impaired glucose tolerance (IGT), group 4 = both IFG and IGT, and group 5 = type 2 diabetes mellitus (T2DM). Results were compared between groups. Results: The mean age of participants included in the study was 50.03 ± 13.62 years. 35.2% were men and 64.7% were women. HbA1c, creatinine, triglyceride, glucose and NHR values increased, while estimated glomerular filtration rate (eGFR) and high density lipoprotein cholesterol (HDL-C) values decreased as the patients progressed from the NGT group to the T2DM group(p

Özet

Giriş: Monosit/HDL-kolesterol oranı (MHO) ve nötrofil/HDL-kolesterol oranı(NHO) kronik hastalıklar için subklinik inflamasyonun basit ve ucuz belirteçleridir. Bu çalışma, farklı glukoz toleranslarına sahip katılımcılarda MHO ve NHO'yu değerlendirmeyi amaçladı. Gereç ve Yöntem: 1112 hasta (erkek / kadın = 392/720) OGTT sonuçlarına göre beş gruba ayrıldı: grup 1 = normal glikoz toleransı (NGT), grup 2 = bozulmuş açlık glikozu (BAG), grup 3 = izole bozulmuş glukoz toleransı (BGT), grup 4 = hem BAG hem de BGT ve grup 5 = tip 2 diabetes mellitus (T2DM). Sonuçlar gruplar arasında karşılaştırıldı. Bulgular: Çalışmaya dahil edilen katılımcıların yaş ortalaması 50,03±13,62 olarak bulundu. %35,2’si erkek %64,7’si kadındı. Hastaların NGT grubundan T2DM grubuna ilerledikçe HbA1c, kreatinin, trigliserit, glukoz ve NHO değerlerinin arttığı, tahmini glomerüler filtrasyon hızı (tGFH) ve yüksek dansiteli lipoprotein kolesterol (HDLK) değerlerinin ise azaldığı görüldü (p

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Cite This Article

AVŞAR, E., AYDEMİR, M., SÖZEL, H., ALEMDAR, M. S. (2022). MONOCYTE / HDL-CHOLESTEROL AND NEUTROPHIL / HDL-CHOLESTEROL RATIOS IN THE DIABETIC PROCESS. İzmir Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 26 - Sayı: 1, 19–29. https://ajindex.com/articles/557711

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