Correlation of serum homocysteın, folat, vitamin B12

In all abortion groups blood homocystein levels are found meaningful higher, blood folat and vitamin B12 levels are found meaningful lower than the levels of control group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Maternal trombofilia and hiperhomocysteinemia are thought to be situated in etiology of abortion.

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Key Findings & Data:Our study's target is to research the relation between abortion and blood homocystein ,folat,vitamin B12, hemostatic parameters and to determine the blood homosistein levels that can show the progress of pregnancy with complication.

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Conclusion & Impact:In all abortion groups blood homocystein levels are found meaningful higher, blood folat and vitamin B12 levels are found meaningful lower than the levels of control group (p

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Maternal trombofilia and hiperhomocysteinemia are thought to be situated in etiology of abortion. By looking to the homocystein level in the first trimester ,a prescience about progress of pregnancy can be provided or not is still a researching subject. Our study's target is to research the relation between abortion and blood homocystein ,folat,vitamin B12, hemostatic parameters and to determine the blood homosistein levels that can show the progress of pregnancy with complication. In all 102 patients which have taken diagnosis of abortion imminens,incomplete abortion and misssed abortion between 5-13 weeks'gestation and 33 healthy pregnant between 5-12 weeks gestation are included to our study. Control group and abortion imminens group are observed to the 20th week of pregnancy . Necessary medikal processes are done to the missed abortion and incomplete abortion groups. In all abortion groups blood homocystein levels are found meaningful higher, blood folat and vitamin B12 levels are found meaningful lower than the levels of control group (p

Özet

Abortus etiyolojik nedenleri arasında maternal trombofilinin ve hiperhomosisteineminin yer aldıgı varsayılmaktadır. Gebeligin ilk üç ayı içerisinde homosistein seviyesine bakılarak gebeligin seyri konusunda öngörü saglanıp saglanamayacagı halen arastırılmakta olan bir konudur. Çalısmamızın amacı hemostaz parametreleri, serum homosistein, folat ve vitamin B12 düzeyleri ile abortus arasındaki iliskiyi arastırmak ve komplikasyonlu gebeligin seyrini belirleyebilecek serum homosistein düzeylerini saptamaktır. Çalısmamıza 5- 13. gebelik haftaları arasındaki abortus imminens, inkomplet abortus ve fetal kalp atımı izlenmeyen missed abortus tanısı alan toplam 102 hasta ve 5-12. gebelik haftaları arasındaki saglıklı 33 gebe dahil edildi. Kontrol grubu ve abortus imminens grubu 20. gebelik haftasına kadar izlendi. Missed abortus ve inkomplet abortus gruplarına gerekli tıbbi girisimler yapıldı. Tüm abortus gruplarında serum homosistein düzeyleri, kontrol grubuna göre anlamlı derecede yüksek, serum folat ve vitamin B12 düzeyleri anlamlı derecede düsük bulundu (p

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Cite This Article

GÜNDOĞDU, F., SOYLU, F., İNCE, M. E., ÇAMLI, M. L., İNCE, F. D., ÖZTÜRK, D., ERKAN, L. (2022). Correlation of serum homocysteın, folat, vitamin B12. İzmir Atatürk Eğitim Hastanesi Tıp Dergisi, Cilt: 46 - Sayı: 4, 144–149. https://ajindex.com/articles/557529

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