Journals / İstanbul Üniversitesi Veteriner Fakültesi Dergisi / 2015 / Cilt: 41 - Sayı: 1

Sütçü İneklerde Doğum Öncesi ve Postpartum Endometritis ve Yumurtalık Kistlerinde IGF-I Düzeylerindeki İlişkinin Değerlendirilmesi

Assessment of Relationship Between IGF-I Concentration Before Parturition and Postpartum Endometritis and Ovarian Cysts in Dairy Cattle

Pages
12–20
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, prepartum IGF-I concentration was the main factor associated with occurrence of endometritis and cystic ovarian disease after calving and it was a notable feature of the current study

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This study was carried out to assess the IGF-I, non-esterified fatty acids (NEFA), beta hydroxybutyrate (BHB) and glucose concentrations during the peripartum period of dairy cows in normal condition, and cows with endometritis puerperalis and cystic ovarian disease.
📊
Key Findings & Data:The study was conducted on 87 lactating Holstein cows in the 9th month of pregnancy in Shiraz, Iran.
💡
Conclusion & Impact:In conclusion, prepartum IGF-I concentration was the main factor associated with occurrence of endometritis and cystic ovarian disease after calving and it was a notable feature of the current study
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

This study was carried out to assess the IGF-I, non-esterified fatty acids (NEFA), beta hydroxybutyrate (BHB) and glucose concentrations during the peripartum period of dairy cows in normal condition, and cows with endometritis puerperalis and cystic ovarian disease. The study was conducted on 87 lactating Holstein cows in the 9th month of pregnancy in Shiraz, Iran. Blood samples were collected every 2 weeks from 2 weeks before until 6 weeks after calving. Two, four and six weeks after calving, palpation of the reproductive tract was performed. Cows were first inspected for the presence of fresh abnormal discharge on the vulva, perineum, or tail then those were examined intra-vaginally. Following inspection, ultrasonographic assessment of uterus and ovaries was also performed and ovarian structures (palpable follicle, CL and cyst) were scanned. Prepartum IGF-I concentration was significantly lower in cows that developed cystic ovaries than non-cystic (35.89±9.09 versus 41.99±3.65 ?g/L) and cows with clinical endometritis early postpartum than normal cows (36.65±5.38 versus 43.64±4.32 ?g/L). Calving-first service interval and ovarian cycle resumption after calving was significantly shorter for cows without clinical endometritis than cows with clinical endometritis. In conclusion, prepartum IGF-I concentration was the main factor associated with occurrence of endometritis and cystic ovarian disease after calving and it was a notable feature of the current study

Özet

Bu çalışma peripartum dönem sırasında normal durumdaki sütçü inekler ile puerperal endometritis ve yumurtalık kisti olan ineklerdeki IGF-1, esterleşmemiş yağ asitleri (NEFA), beta hidroksibutirat (BHB) ve glukoz düzeylerinin değerlendirilmesi için gerçekleştirilmiştir. Çalışma İran, Şiraz'da gebeliklerinin 9. ayında bulunan 87 adet laktasyondaki Siyah Alaca (doğum sayısı: 1-7) inekte yürütülmüştür. Buzağı doğumlarından 2 hafta öncesinden başlayarak doğumdan 6 hafta sonrasına kadar her 2 haftada bir kan örnekleri alınmıştır. Buzağı doğumlarından iki, dört ve altı hafta sonra ineklerin genital organlarının durumları rektal palpasyon ile değerlendirilmiştir. İneklerin vulva, perineum ya da kuyruk bölgesinde taze anormal akıntı varlığı yönünden incelendikten sonra intravajinal incelemesi de yapılmıştır. İnceleme sonrası, rahim ve yumurtalıkların ultrasonografik değerlendirilmesi yapılmış ve yumurtalık yapıları (palpe edilebilen folikül, CL ve kist) taranmıştır. Prepartum IGF-I düzeyleri kistik yumurtalıkları oluşan ineklerde kistik olmayanlara göre (35,89±9,09'a karşı 41,99±3,65 ?g/L) ve erken postpartum dönemde klinik endometritli ineklerde sağlıklı ineklere göre (36,65±5,38'a karşı 43,64±4,32 ?g/L) anlamlı olarak daha düşük bulunmuştur. Klinik yönden endometritli olmayan ineklerde doğum sonrası ilk tohumlama aralığı ve doğum sonrası östrus siklusunun yeniden başlama sürelerinin klinik yönden endometritli ineklere göre anlamlı olarak daha kısa bulunmuştur. Sonuç olarak, prepartum IGF-I düzeyi doğum sonrası endometritis ve kistik ovaryumun oluşumu ile ilişkili temel faktördür ve ortaya konulan bu sonuç çalışmanın önemli bir özelliğidir.

🔖

Cite This Article

AHMADI, M. R., GHEISARI, H. R., KADIVAR, A. (2022). Sütçü İneklerde Doğum Öncesi ve Postpartum Endometritis ve Yumurtalık Kistlerinde IGF-I Düzeylerindeki İlişkinin Değerlendirilmesi. İstanbul Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 41 - Sayı: 1, 12–20. https://ajindex.com/articles/555108

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Battaglia, D.F., Krasa, H.B., Padmanabhan, V., Viguie, C., Karsch, F.J., 2000. Endocrine alterations that underlie endotoxin-induced disruption of the follicular phase in ewes. Biology of Reproduction 62, 45-53.
  2. Beam, S., Butler, W., 1998 Energy balance, metabolic hormones, development in dairy cows fed prilled lipid. Journal of Dairy Science 81, 121-131. postpartum follicular Cairoli, F., Comin, A., Scocca, S., Fazzini, U., De Amicis, I., Battocchio, M., 2008. Hormonal and metabolic profiles in post partum ovarian cysts in dairy cows. Veterinary Research Communication 32, Supplement 1, S123-125. Clark, R., 1997. The somatogenic hormones and insulin-like growth factor-1: stimulators of lymphopoiesis and immune function. Endocrine Reveiw 18, 157-179.
  3. Edmonson, A.J., Lean, I.J., Weaver, L.D., Farver, T., Webster, G., 1989. A body condition scoring chart for Holstein Dairy cows. Journal of Dairy Science 72, 68-78.
  4. Fenwick, M., A., Fitzpatrick, R., Kenny, D.A., Diskin, M.G., Patton, J., Murphy, J.J., Wathes, D.C., 2008. Interrelationships between negative energy balance (NEB) and IGF regulation in liver of lactating dairy cows. Domestic Animal Endocrinology 35, 31-44.
  5. Gilbert, R.O., Shin, S.T., Guard, C.L., Erb, H.N., Frajblat, M., 2005. Prevalence of endometritis and its effects on reproductive Theriogenology 64, 1879-1888. of dairy cows. Heemskerk, V., Daemen, M., Buurman, W., 1999. Insulin-like growth factor-1 (IGF-1) and growth hormone (GH) in immunity and inflammation. Cytokine and Growth Factor Reviews 10, 5-14.
  6. Heuwieser, W., Tenhagen, B.A., Tischer, M., Luhr, J., Blum, H., 2000. Effect of three programmes for the treatment of endometritis on the reproductive performance of a dairy herd. Veterinary Record 146, 338-341.
  7. Kadivar, A., Ahmadi, M.R., Gheisari, H.R., Nazifi, S., 2012. Assessment of IGF-I as a factor influencing postpartum reproductive performance and ovarian condition in dairy cattle. Comparative Clinical Pathology 21, 589-596.
  8. Kawashima, C., Fukihara, S., Maeda, M., Kaneko, E., Montoya, C.A., Matsui, M., Shimizu, T., Matsunaga, N., Kida, K., Miyake, Y., Schams, D., Miyamoto, A., 2007. Relationship between metabolic hormones and ovulation of dominant follicle during the first follicular wave post-partum in high-producing dairy cows. Reproduction 133, 155-163.
  9. LeBlanc, S.J., Duffield, T.F., Leslie, K.E., Bateman, K.G., Keefe, G.P., Walton, J.S., Johnson, W.H., 2002. The effect of treatment of clinical endometritis on reproductive performance i