Journals / İstanbul Tıp Dergisi / 2010 / Cilt: 11 - Sayı: 2

The levels of fibrinogen and CRP in patients with ischemic stroke

İskemik inmeli hastalarda fibrinojen ve CRP düzeyleri

Pages
62–64
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

CONCLUSION: The conclusions were discussed with literature.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Aterosclerosis is a main pathogenetic process in stroke development. ln aterosclerosis there can be mild increase in acure phase reactants due to chronic inflammation and this can determine the prognosis of the patient.
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Key Findings & Data:This acute increase in fibrinogen in patients with stroke can cause acule phase reaction secondary to ischemia and/or brain tissue necrosis.
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Conclusion & Impact:CONCLUSION: The conclusions were discussed with literature.
🔬Design:Research Article
📍Scope:2005 Verileri
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Aterosclerosis is a main pathogenetic process in stroke development. ln aterosclerosis there can be mild increase in acure phase reactants due to chronic inflammation and this can determine the prognosis of the patient. Acute phase reactants can be concerned with the prognosis of the patients with stroke. However there are different conclusions in literature. But also it is claimed as CRP (C- reactive protein) doesn't give idea about the prognosis of cerebrovascular events. This acute increase in fibrinogen in patients with stroke can cause acule phase reaction secondary to ischemia and/or brain tissue necrosis. But this can also be the direct reason of stroke. METHODS: The goal of our study is to show the levels of fibrinogen and CRP in patients with stroke. And to determine the relation between the prognosis and the jibrinogen value in the first 24 hours. RESULTS: 34 patients were taken to our study. They applied in the first 24 hours of acute ischemic stroke hetween the 2nd and 7th months in 2005. 21 of the patients were female, 13 were male. There was hypertension in 27 patients, diabetes mellitus in 12 patients, ischemic heart disease in 11 patients, smoking in 10 patients, and alcohol use in 4 patients. CONCLUSION: The conclusions were discussed with literature.

Özet

AMAÇ: Ateroskleroz, inme gelişiminde temel patogenetik proçestir. Aterosklerotik damar hastalığı varlığında, altta yatan kronik enflamasyondan dolayı akutfaz reaktanlarında hafifderecede bir artış olabileceği ve bunun hastanın prognozunu belirleyebileceği belirtilmiştir. İnmeli hastalarda prognozun akut faz reaktanları ile ilişkili olabileceği öne sürülmüştür. Ancak literatürde bu konuda birbirinden farklı sonuçlar vardır. Bunun tersi, yani C-reaktif proteinin (CRP)serebrovasküler hastalıklarda prognoz hakkında fikir vermediği de iddia edilmiştir. Öte yandan, inmeli hastalarda fibrinojendeki bu akut artışın iskemi ve/veya beyin dokusu nekrozuna sekonder akut faz reaksiyonu olabileceği gibi inmenin direkt bir nedeni de olabileceği belirtilmiştir. YÖNTEMLER: Çalışmamızın amacı iskemik inmeli hastalarda fibrinojen ve CRP düzeylerinin ölçülmesi ve ilk 24 saat içindeki fibrinojen düzeyinin prognozla ilişkisinin saptanmasıdır. BULGULAR: Çalışmaya 2005 yılı 2. ve 7. ayları arasında S.B. İstanbul Eğitim ve Araştırma Hastanesi Nöroloji Kliniğine ilk 24 saat içinde olan akut iskemik inme ile başvuran 34 hasta alındı. Bunların 21 tanesi kadın, 13 tanesi erkekti. 27 hastada hipertansiyon, 12 hastada diabetes mellitus, 11 hastada iskemik kalp hastalığı vardı. 10 hastada sigara içme, 4 hastada alkol kullanım hikayesi mevcuttu. SONUÇ: Sonuçlar literatürle birlikte tartışıldı.

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Cite This Article

TEKEŞİN, A., TAŞKIRAN, E., SAÇAK, Ş., MANGA, F., YAĞIZ, O. (2022). The levels of fibrinogen and CRP in patients with ischemic stroke. İstanbul Tıp Dergisi, Cilt: 11 - Sayı: 2, 62–64. https://ajindex.com/articles/552602

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