Journals / İstanbul Tıp Dergisi / 2010 / Cilt: 11 - Sayı: 1

case report: Calvarial mass as the first clinical presentation of a renal cell carcinoma

Kalvaryum tutulumu ile ortaya çıkan renal hücreli karsinom (Olgu sunumu)

Pages
33–36
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We report a case RCC with calvaryal metastasis revealed before the primary tumor become apparent.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Renal cell carcinoma (RCC) has a high propensity for early metastasis and evidence of metastases is present in about one third of patients at presentation.
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Key Findings & Data:Osseous metastasis occurs in 20%-60% of patients with RCC.
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Conclusion & Impact:We report a case RCC with calvaryal metastasis revealed before the primary tumor become apparent.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Renal cell carcinoma (RCC) has a high propensity for early metastasis and evidence of metastases is present in about one third of patients at presentation. RCC frequently manifests first as an osseous metastasis from a clinically occult primary tumor. Osseous metastasis occurs in 20%-60% of patients with RCC. Most of the metastases are aggressive lytic lesions, usually with cortical erosion or destruction. The most common metastasis from RCC is a lytic destructive lesion in the pelvis or sacrum. CalvarÝum is an unusual site of RCC metastasis. The first case of calvarial RCC metastasis has been reported in 1960 by Melicov and Uson. The best treatment for a single metastasis is surgical excision. We report a case RCC with calvaryal metastasis revealed before the primary tumor become apparent.

Özet

Renal hücreli karsinomlar (RHK), erken metastaz yapma özelliğinde olup, olguların 1/3’ünde klinik olarak okült primer tümörün, osseöz metastazı ile (sıklıkla soliter) ortaya çıkar. RHK’lı olguların %20-60 ında kemik metastazı görülür. Metastazlar kortikal erozyon ve destrüksiyona neden olan litik lezyonlar şeklindedir. Genellikle pelvis ve sakrumda yerleşirler, kalvaryum seyrek tutulumu seyrektir. RHK’nın kalvaryum metastazı ilk olarak 1960 yılında Melicov ve Uson tarafından bildirilmiştir. Soliter kemik metastazlarında en iyi tedavi lezyonun cerrahi olarak çıkarılmasıdır. Bu çalışmada da kalvaryum metastazı ile ortaya çıkan RHK olgusu sunuldu.

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Cite This Article

ÖZTÜRK, A., BARUT, A. Y., DEMİRCİ, Ü. (2022). case report: Calvarial mass as the first clinical presentation of a renal cell carcinoma. İstanbul Tıp Dergisi, Cilt: 11 - Sayı: 1, 33–36. https://ajindex.com/articles/552578

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