Journals / İstanbul Medical Journal / 2014 / Cilt: 15 - Sayı: 1

The Correlation between Cerebrovascular Disease and HBA1C Levels in Patients with Type 2 Diabetes Mellitus

Tip 2 Diyabetli Hastalarda Serebrovasküler Hastalık ile HBA1C Seviyeleri Arasındaki Korelasyon

Pages
40–42
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We believe that further studies withlarger patient groups should be conducted for more precise results.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, we aimed to investigate the relation of cerebrovasculardisease with HbA1c levels in patients with type 2 diabetes mellitus.Methods: Tip 2 diabetic patients with iron deficiency anemia, high triglyceridelevels, uremia, high bilirubin levels, chronic use of salicylates andopioids, and chronic alcohol abuse, which could have an impact on HbA1clevels, were excluded from the study. 60 diabetic patients with HbA1c levelsmeasured routinely,whose initial diagnosis were ischemic stroke, wererecruited to the study. 34 patients were female, while 26 were male.
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Key Findings & Data:HbA1clevels were measured using high performance liquid chromatography.Results: Using our hospital laboratory reference ranges, in 63% of the patientsHbA1c levels were found to be high.However, according to an anotherreference range in the literature the upper limit for normal levelswas accepted as 1.5 times more than our limit.
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Conclusion & Impact:We believe that further studies withlarger patient groups should be conducted for more precise results.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, we aimed to investigate the relation of cerebrovasculardisease with HbA1c levels in patients with type 2 diabetes mellitus.Methods: Tip 2 diabetic patients with iron deficiency anemia, high triglyceridelevels, uremia, high bilirubin levels, chronic use of salicylates andopioids, and chronic alcohol abuse, which could have an impact on HbA1clevels, were excluded from the study. 60 diabetic patients with HbA1c levelsmeasured routinely,whose initial diagnosis were ischemic stroke, wererecruited to the study. 34 patients were female, while 26 were male. HbA1clevels were measured using high performance liquid chromatography.Results: Using our hospital laboratory reference ranges, in 63% of the patientsHbA1c levels were found to be high.However, according to an anotherreference range in the literature the upper limit for normal levelswas accepted as 1.5 times more than our limit. According to this literature,HbA1c levels were found to be high in 43% of patients. HbA1c levels wereabove 4,2-8% in 34 out of 60 patients, 8-12 % in 21 patients,and more than12% in 5 patients.Conclusion: No correlation was found between glycemic control and developmentof cerebrovascular disease. We believe that further studies withlarger patient groups should be conducted for more precise results.

Özet

Amaç: Bu çalışmada, Tip 2 diyabetli hastalarda serebrovasküler hastalıkile HbA1seviyeleri arasındaki ilişkiyi araştırmayı amaçladık.Yöntemler: HbA1c düzeylerini etkilediği bilinen demir eksikliği anemisi,trigliserid düzeyleri yüksekliği, üremisi, bilirubin düzeyleri yüksekliğisaptanan ve kronik salisilat, alkol ve opiat kullanımı olan Tip 2 diyabetikhastalar dışlanarak; iskemik inme tanısı ile yatırılan diabetik hastalardaHbA1c ölçümü yapılan 60 hasta çalışmaya alındı. 34 hasta kadın, 26 hastaerkekti. HbA1c ölçümlerinde yüksek performanslı sıvı kromatografi metodukullanıldı.Bulgular: Hastanemiz laboratuarının referans değerleri kullanılarak yapılanölçümde hastaların %63'ünde yüksek HbA1c seviyeleri saptandı. Ancakbir kaynağa göre HbA1c'nin normal değeri üst sınırın 1,5 üstü kabuledilmektedir. Bu şekilde değerlendirme yapıldığında hastaların %43'ündeyüksek değerler bulunmaktadır. Bizim hastalarımızdaki HbA1c değerleri60 hastanın 34'ünde %4,2-8, 21'inde %8-12,5'inde %12 ve üstünde idi.Sonuç: Glisemi kontrolü ile serebrovasküler hastalık gelişmesi arasında birilişki kurulamamıştır. Daha net sonuç elde edebilmek için daha fazla hastagrubu ile çalışmalar yapılmasının doğru olacağının kanısındayız.

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Cite This Article

DOĞAN, B., TEKEŞİN, A., POLAT, H., YAĞIZ, O. (2022). The Correlation between Cerebrovascular Disease and HBA1C Levels in Patients with Type 2 Diabetes Mellitus. İstanbul Medical Journal, Cilt: 15 - Sayı: 1, 40–42. https://ajindex.com/articles/552236

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