Journals / İstanbul Medical Journal / 2014 / Cilt: 15 - Sayı: 1

Endorectal Surface Coil MRI of Prostate Cancer: Comparison of Diffusion-Weighted Imaging (DWI) with Prostate-Specific Antigen (PSA) Values and Histopathologic Diagnosis

Prostat Kanserinin Endorektal Koilli Manyetik Rezonans Görüntüleme (MRG) ile Değerlendirilmesi: Difüzyon Ağırlıklı Görüntüleme (DAG) ile Prostat Spesifik Antijen (PSA) Değerleri ve Histopatolojik Tanının Karşılaştırılması

Pages
43–46
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our re- sults showed that DWI improves the diagnosis and detection of prostate carcinoma located in the peripheral zone.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Prostate cancer is the third leading cause of death and is the most common genitourinary malignancy in men.
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Key Findings & Data:Methods: This study was performed retrospectively between 2010-2011 to 38 male patients who have 66.8 years age average , according to their prostate MRI findings with an endorectal surface coil correlation with clinical findings.
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Conclusion & Impact:Our re- sults showed that DWI improves the diagnosis and detection of prostate carcinoma located in the peripheral zone.
🔬Design:Research Article
📍Scope:2010-2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Prostate cancer is the third leading cause of death and is the most common genitourinary malignancy in men. The aim of this study is to evaluate the contribution of diffusion-weighted imaging (DWI) in the diagnosis of peripheral zone located prostate carcinoma while performing endorectal surface coil magnetic resonance imagining (MRI). Methods: This study was performed retrospectively between 2010-2011 to 38 male patients who have 66.8 years age average , according to their prostate MRI findings with an endorectal surface coil correlation with clinical findings. Results: In this study all of the patients' prostate carcinoma diagnosis were confirmed histopathologically. The mean Gleason score was 7 (4+3). In routine sequences of MRI assessment, we found an increase of the pros- tate diamaters, generally homogenous SI in the central zone and heter- ogenous SI in the peripheral zone. On T1 WI there was high SI because of pervious core biopsy and secondary hemorrhage, on T2 WI there was heterogenous SI. This area was heterogenous on contrast enhanced se- ries because of different hemorrhagic elements. On DWI series there was restricted diffusion at this site and hypointensity on ADC mapping. After ADC mapping of our patients, mean ADC values were measured as 0.98±0.36 x10-3 mm2/s. Conclusion: Currently, prostate MRI with an endorectal surface coil is rec- ommended if cancer is suspected despite negative biopsy findings and for local staging of the cancer. However, a prebiopsy MRI has not been indicated for the detection and localization of cancer. DWI with ADC mea- surement is useful to distinguish between benign and malignant lesions. Compared with T2WI, the addition of an ADC map improves the diagnostic performance of MRI in prostate cancer detection and localization. Our re- sults showed that DWI improves the diagnosis and detection of prostate carcinoma located in the peripheral zone.

Özet

Amaç: Prostat kanseri erkeklerde en sık görülen genitoüriner maligniteolup üçüncü en sık rastlanan ölüm nedenidir. Bu çalışmanın amacı endorektalkoil kullanılarak gerçekleştirilen prostat manyetik rezonans görüntüleme(MRG) olgularımızda periferal zon yerleşimli prostat kanseritanısına difüzyon ağırlıklı görüntüleme DAG'nin katkısını araştırmaktır.Yöntemler: Bu çalışma 2010-2011 yılları arasında hastanemize başvuranve yaş ortalamaları 66,8 olan (49 ile 85 arası) 38 erkek olguya endorektalkoil kullanılan prostat MRG bulgularının klinik bulgularıyla birlikte değerlendirilmesiile geriye dönük olarak gerçekleştirilmiştir.Bulgular: Çalışmaya dahil edilen olgularımızın tamamında histopatolojikolarak prostat karsinomu tanısı doğrulanmıştı. Olgularımızın ortalamaGleason skoru 7 (4+3) idi. Ele aldığımız olguların MRG değerlendirmesindealışılagelen sekanslarda prostat boyutlarında artış, santral zonda genelliklehomojen, periferik zonda homojen olmayan sinyal intensiteleri(Sİ) izlenmekteydi. T1 ağırlıklı görüntülerde (T1AG) genellikle girişimselişleme ve ikincil hemorajiye bağlı hafif Sİ artışı, T2AG'lerde heterojen Sİve kontrastlı görüntülerde farklı hemorajik bileşenlere bağlı heterojenkontrastlanma paterni dikkati çekmekteydi. DAG'lerde kitlesel lezyonunbulunduğu alanlarda difüzyon kısıtlaması ve bu alana ait ADC haritalamadahipointensite gözlenmekteydi. Olgularımızın ADC haritalarında yaptığımızölçümler sonrasında ortalama ADC değerleri yaklaşık 0,98±0,36x10-3mm2/s olarak hesaplandı.Sonuç: Endorektal koilli prostat MRG prostat biyopsi sonucu negatif gelenolgularda ve prostat kanserinin yerel evrelemesinin yapılmasında önerilmektedir.Ancak biyopsi öncesi prostat MRG kanser tarama ve evrelemedegerekli değildir. DAG'ye eklenen ADC değerleri malign-benign prostat kitleleriayırımında yardımcı olmaktadır. T2AG'ye eklenen ADC haritalamasıprostat kanseri tanısal doğruluk oranını arttırmaktadır. Sonuçlarımız, periferikzon yerleşimli prostat kanseri taramasında ve yerleşimini belirlemedeDAG'nin tanıya yardımcı olduğunu ortaya çıkarmıştır.

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Cite This Article

KARAGÖZ, Y., ŞİMŞEK, A., AYBAR, M. D., TURNA, Ö., RAKICI, İ. T. (2022). Endorectal Surface Coil MRI of Prostate Cancer: Comparison of Diffusion-Weighted Imaging (DWI) with Prostate-Specific Antigen (PSA) Values and Histopathologic Diagnosis. İstanbul Medical Journal, Cilt: 15 - Sayı: 1, 43–46. https://ajindex.com/articles/552179

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