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Journals / İstanbul Medical Journal / 2016 / Cilt: 17 - Sayı: 2

Baş-boyun Skuamöz Hücreli Karsinomlarında Lokal Nüksün Saptanmasında Difüzyon Ağırlıklı MR ve FDG PET/BT'nin Tanısal Performansı

Diagnostic Performance of Diffusion-Weighted MRI and FDG PET/CT for Detecting the Local Recurrence of Head and Neck Squamous Cell Carcinoma

İbrahim İlker ÖZ
Mustafa Çağatay BÜYÜKUYSAL
Murat DAMAR
Yavuz Sami SALİHOĞLU
Oktay ERDEM
İsmail ŞERİFOĞLU
Aykut Erdem DİNÇ
Rabiye USLU
Pages
48–53
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

PET/CT images were acquired after the administration of 3.7 MBq/kg of fluorine-18-fluorodeoxyglucose, and the images were acquired 1 h later.Results: The apparent diffusion coefficient (ADC)mean values of the recurrence group were significantly lower than those of the post-treatment changes group (0.773 vs. 1.588×10-3 mm2/s, respectively; p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To compare the efficacy between diffusion-weighted magnetic resonance imaging (DW-MRI) and positron emission tomography/computed tomography (PET/CT) in detecting the local recurrence of head and neck squamous cell carcinoma (HNSCC) following treatment in the same patient group.
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Key Findings & Data:The median delay times between radiotherapy and MRI and between MRI and FDG PET/CT were 71 days (range: 43-98 days) and 75 days (range: 44-103 days), respectively.
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Conclusion & Impact:PET/CT images were acquired after the administration of 3.7 MBq/kg of fluorine-18-fluorodeoxyglucose, and the images were acquired 1 h later.Results: The apparent diffusion coefficient (ADC)mean values of the recurrence group were significantly lower than those of the post-treatment changes group (0.773 vs. 1.588×10-3 mm2/s, respectively; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To compare the efficacy between diffusion-weighted magnetic resonance imaging (DW-MRI) and positron emission tomography/computed tomography (PET/CT) in detecting the local recurrence of head and neck squamous cell carcinoma (HNSCC) following treatment in the same patient group. Methods: Twenty-three patients who had biopsy-proven HNSCC were enrolled. All patients were treated with radiotherapy and followed up with MRI and PET/CT. The median delay times between radiotherapy and MRI and between MRI and FDG PET/CT were 71 days (range: 43-98 days) and 75 days (range: 44-103 days), respectively. Diffusion-weighted single-shot echo planar imaging was performed before contrast injection at b values of 0 and 1000 s/mm2. PET/CT images were acquired after the administration of 3.7 MBq/kg of fluorine-18-fluorodeoxyglucose, and the images were acquired 1 h later.Results: The apparent diffusion coefficient (ADC)mean values of the recurrence group were significantly lower than those of the post-treatment changes group (0.773 vs. 1.588×10-3 mm2/s, respectively; p

Özet

Amaç: Baş-boyun skuamöz hücreli karsinom (SCC) lokal nüksün saptanmasında difüzyon ağırlıklı manyetik rezonans görüntüleme (DA-MRG) ve pozitron emisyon tomografi/bilgisayarlı tomografi (PET/BT) etkinliğini karşılaştırmak.Yöntemler: Baş-boyun SCC tanısı biyopsi ile kanıtlanmış ve radyoterapi ile tedavi edilen 23 hasta çalışmaya dahil edildi. Takipte tüm hastalardan MRG ve PET/BT incelemesi yapıldı. Tedavinin tamamlanması ile MR ve PET/BT incelemleri arasındaki ortalama süre sırasıyla 70,30 gün ve 76,34 gün idi. Difüzyon ağırlıklı single-shot eko planar görüntüleme 0 ve 1000 sn/mm2 b değerlerinde kontrast enjeksiyonundan önce yapıldı. PET/BT görüntüleri flor-18-fluorodeoksiglukoz (3.7 MBq/kg) verilmesinden 1 saat sonra görüntüler elde edildi.Bulgular: Nüks saptanan hastalarda ADCortalama değerleri saptanmayan hastalarla karşılaştırıldığında istatistiksel olarak anlamlı derecede düşük bulunmuştur (0,773'e karşı 1,588 x10-3/mm2 sırasıyla, p

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Cite This Article

ÖZ, İ. İ., BÜYÜKUYSAL, M. Ç., DAMAR, M., SALİHOĞLU, Y. S., ERDEM, O., ŞERİFOĞLU, İ., DİNÇ, A. E., USLU, R. (2022). Baş-boyun Skuamöz Hücreli Karsinomlarında Lokal Nüksün Saptanmasında Difüzyon Ağırlıklı MR ve FDG PET/BT'nin Tanısal Performansı. İstanbul Medical Journal, Cilt: 17 - Sayı: 2, 48–53. https://ajindex.com/articles/552107

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References (11)

  1. Tshering Vogel DW, Zbaeren P, Geretschlaeger A, Vermathen P, De Keyzer F, Thoeny HC. Diffusion-weighted MR imaging including bi- exponential fitting for the detection of recurrent or residual tumour after (chemo)radiotherapy for laryngeal and hypopharyngeal cancers. Eur Radiol 2013
  2. [CrossRef] Hwang I, Choi SH, Kim YJ, Kim KG, Lee AL, Yun TJ, et al. Differentiation of recurrent tumor and posttreatment changes in head and neck squa- mous cell carcinoma: application of high b-value diffusion-weighted imaging. AJNR Am J Neuroradiol 2013
  3. [CrossRef] Abgral R, Querellou S, Potard G, Le Roux PY, Le Duc-Pennec A, Marianovski R, et al. Does 18F-FDG PET/CT improve the detection of posttreatment re- currence of head and neck squamous cell carcinoma in patients negative for disease on clinical follow-up? J Nucl Med 2009
  4. [CrossRef] Razek AAKA, Kandeel AY, Soliman N, El-Shenshawy HM, Kamel Y, Nada N, et al. Role of diffusion-weighted echo-planar MR imaging in differentiation of residual or recurrent head and neck tumors and posttreatment changes. American journal of neuroradiology 2007
  5. [CrossRef] Razek AA. Diffusion-weighted magnetic resonance imaging of head and neck. J Comput Assist Tomogr 2010
  6. [CrossRef] Thoeny HC, De Keyzer F, King AD. Diffusion-weighted MR imaging in the head and neck. Radiology 2012
  7. [CrossRef] Payne KF, Haq J, Brown J, Connor S. The role of diffusion-weighted magnetic resonance imaging in the diagnosis, lymph node staging and assessment of treatment response of head and neck cancer. Int J Oral Maxillofac Surg 2015
  8. [CrossRef] Choi SH, Paeng JC, Sohn CH, Pagsisihan JR, Kim YJ, Kim KG, et al. Cor- relation of 18F-FDG uptake with apparent diffusion coefficient ratio measured on standard and high b value diffusion MRI in head and neck cancer. J Nucl Med 2011
  9. [CrossRef] Varoquaux A, Rager O, Lovblad KO, Masterson K, Dulguerov P, Ratib O, et al. Functional imaging of head and neck squamous cell carcinoma with diffusion-weighted MRI and FDG PET/CT: quantitative analysis of ADC and SUV. Eur J Nucl Med Mol Imaging 2013
  10. [CrossRef] Burger IA, Huser DM, Burger C, von Schulthess GK, Buck A. Repeatability of FDG quantification in tumor imaging: averaged SUVs are superior to SUV_____ sub> max_____/sub>. Nucl Med Biol 2012
  11. [CrossRef] Nakajo M, Nakajo M, Kajiya Y, Tani A, Kamiyama T, Yonekura R, et al. FDG PET/CT and diffusion-weighted imagin