Journals / İstanbul Medical Journal / 2016 / Cilt: 17 - Sayı: 2

Serum Vitamin D and Parathyroid Hormone Levels in Patients with Obstructive Sleep Apnea Syndrome

Obstrüktif Uyku Apne Sendromlu Hastalarda Serum Vitamin D ve Parathormon Düzeyleri

Pages
64–67
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Serum vitamin D levels were significantly lower in the OSAS group than in the control group (22.4±7.5 ng/mL vs. 31±7.9 ng/mL, respectively; p

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: An increase in sympathetic activity caused by intermittent hypoxia and reoxygenation that develops an obstruction of the upper respiratory tract in obstructive sleep apnea syndrome (OSAS) results in cardiovascular and metabolic changes.
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Key Findings & Data:Methods: The study population comprised 103 male patients with newly diagnosed OSAS and 58 male non-apnoeic controls matched for age, sex, and body mass index (BMI).
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Conclusion & Impact:Serum vitamin D levels were significantly lower in the OSAS group than in the control group (22.4±7.5 ng/mL vs. 31±7.9 ng/mL, respectively; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: An increase in sympathetic activity caused by intermittent hypoxia and reoxygenation that develops an obstruction of the upper respiratory tract in obstructive sleep apnea syndrome (OSAS) results in cardiovascular and metabolic changes. This study aimed to assess the effects of OSAS on serum vitamin D and parathyroid hormone (PTH) levels. Methods: The study population comprised 103 male patients with newly diagnosed OSAS and 58 male non-apnoeic controls matched for age, sex, and body mass index (BMI). Serum calcium, phosphorus, vitamin D, and PTH levels were measured. Results: There were no significant differences between patients with OSAS and the controls in terms of age, sex, BMI, smoking status, hypertension, and hyperlipidemia. Serum vitamin D levels were significantly lower in the OSAS group than in the control group (22.4±7.5 ng/mL vs. 31±7.9 ng/mL, respectively; p

Özet

Amaç: Obstrüktif uyku apne sendromunda (OUAS) tekrarlayıcı solunum durmaları sonucu gelişen hipoksi-reoksijenizasyon peryodları sonucu artan sempatik aktivite artışı çeşitli kardiyovasküler ve metabolik değişikliklere neden olmaktadır. Bu çalışmada OUAS'ın vitamin D ve parathormon (PTH) üzerine etkisini incelemeyi amaçladık. Yöntemler: Çalışmaya polisomnografi ile yeni tanı alan 103 erkek, OUAS grubu olarak ve yaş, cinsiyet, vücut kitle indeksi (VKİ) açısından eşleşen ve apnesi olmayan 58 erkek, kontrol grubuna dahil edildi. Serum kalsiyum, fosfor, vitamin D ve PTH düzeyleri ölçüldü. Bulgular: Yaş, VKİ, sigara kullanımı, hipertansiyon ve hiperlipidemi açı- sından OUAS ve kontrol gurubu arasında anlamlı fark saptanmadı. Vitamin D düzeyleri OUAS gurubunda kontrol gurubuna kıyasla anlamlı olarak daha düşük iken (sırasıyla 22,4±7,5 ng/mL, 31±7,9 ng/mL, p

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Cite This Article

ÖRNEK, T., ATALAY, F., UYGUR, F., TANRIVERDİ, H., BAKİ, A. E. (2022). Serum Vitamin D and Parathyroid Hormone Levels in Patients with Obstructive Sleep Apnea Syndrome. İstanbul Medical Journal, Cilt: 17 - Sayı: 2, 64–67. https://ajindex.com/articles/552105

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