Journals / İstanbul Medical Journal / 2017 / Cilt: 18 - Sayı: 4

Kolonun Meduller Karsinomu; Nadir Bir Olgu

Colonic Medullary Carcinoma: A Rare Case

Pages
251–254
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Resection of the specimen revealed medullary co- lonic carcinoma

📌 3 Key Takeaways

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Objective & Hypothesis:Medullary carcinoma is a rare subtype of colorectal cancer making up less than 0.1% of all colorectal malignancies.
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Key Findings & Data:In our case, the patient presented with complaints of abdominal pain and rectal bleeding due to a 5 cm wide colonic mass located at the transverse colon.
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Conclusion & Impact:Resection of the specimen revealed medullary co- lonic carcinoma
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Medullary carcinoma is a rare subtype of colorectal cancer making up less than 0.1% of all colorectal malignancies. This subtype can be confused with poorly differentiated colorectal carcinoma due to undifferentiated complexion morphology and high mitotic activity. Medullary carcinoma is a subtype of colonic adenocarcinoma with a better prognosis than other subtypes. This subtype is important be- cause of the expansive growth pattern and high microsatellite insta- bility. Medullary carcinoma is often right sided and is more frequent in older females and has lower incidence of lymph node metastases. In our case, the patient presented with complaints of abdominal pain and rectal bleeding due to a 5 cm wide colonic mass located at the transverse colon. Resection of the specimen revealed medullary co- lonic carcinoma

Özet

Medüller karsinomlar tüm kolorektal kanserlerin % 0.1'inden azını oluşturan ve nadir saptanan tümörlerdir. Bu tümörlerin andiferansiye görünümü ve yüksek mitotik aktivitesi nedeni ile özellikle kötü diferan- siye kolorektal karsinomlar ile tanı karışıklıklarına yol açabilmektedir. Andiferansiye görünümüne karşın prognozu iyi olan kolonik adenokar- sinomların bir alt tipidir. Solid büyüme paterni göstermesi ve yüksek mikrosatellit instabiliteye sahip olması medüller karsinomları diğer kolorektal karsinomlardan ayıran önemli özelliklerdir. Sıklıkla sağ ko- londa yerleşir, ileri yaş bayan hastalarda görülür ve lenf nodu metastaz insidansı düşük olan tümörlerdir. Bu olguda, karın ağrısı ve rektal kana- ma şikayeti ile başvuran, transvers kolon lokalizasyonunda 5 cm çaplı kitle lezyonu saptanan, rezeksiyon sonrası patoloji sonucu kolonun me- düller kanseri olarak gelen hastayı sunmayı amaçladık

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Cite This Article

CİN, N., DURAK, E., BAĞ, H., AVCI, A., KAR, H., PEKER, Y. (2022). Kolonun Meduller Karsinomu; Nadir Bir Olgu. İstanbul Medical Journal, Cilt: 18 - Sayı: 4, 251–254. https://ajindex.com/articles/552071

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References (1)

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