Journals / İstanbul Medical Journal / 2019 / Cilt: 20 - Sayı: 1

Diagnostic Performance of Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio in Endometrioma

Endometriomada Nötrofil/Lenfosit Oranı ve Trombosit/Lenfosit Oranının Tanı Performansı

Pages
13–16
Publication Date
2022-10-19
DOI
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⚡ TL;DR(Too Long; Didn't Read)

NLR ratio was found to be statisticallysignificantly higher in bilateral endometriomas compared tounilaterals.Conclusion: Although NLR was not found to be elevated inpatients with endometrioma, it was found to be affected frombilaterality.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: To evaluate whether neutrophil/lymphocyteratio (NLR) and platelet/lymphocyte ratio (PLR) have diagnosticvalue in endometrioma, which is a chronic inflammatorydisease.Methods: A total of 187 patients who underwent surgery foradnexal mass, 97 patients diagnosed with endometriomaand 90 patients with benign cyst (corpus luteum, serouscysts or functional cysts), were included in this retrospective,comparative case series.
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Key Findings & Data:NLR and PLR values obtained frompreoperative complete blood count parameters were comparedbetween the two groups.Results: There was no statistically significant difference betweenendometrioma and benign cyst groups regarding meanage (34.8±8.93 and 34.0±8.59 years, respectively, p=0.88).Fourteen point four percent (n=14) of the endometriomaswere bilateral.
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Conclusion & Impact:NLR ratio was found to be statisticallysignificantly higher in bilateral endometriomas compared tounilaterals.Conclusion: Although NLR was not found to be elevated inpatients with endometrioma, it was found to be affected frombilaterality.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: To evaluate whether neutrophil/lymphocyteratio (NLR) and platelet/lymphocyte ratio (PLR) have diagnosticvalue in endometrioma, which is a chronic inflammatorydisease.Methods: A total of 187 patients who underwent surgery foradnexal mass, 97 patients diagnosed with endometriomaand 90 patients with benign cyst (corpus luteum, serouscysts or functional cysts), were included in this retrospective,comparative case series. NLR and PLR values obtained frompreoperative complete blood count parameters were comparedbetween the two groups.Results: There was no statistically significant difference betweenendometrioma and benign cyst groups regarding meanage (34.8±8.93 and 34.0±8.59 years, respectively, p=0.88).Fourteen point four percent (n=14) of the endometriomaswere bilateral. The mean endometrioma size was 6.0±2.74cm and 27.8% (n=27) of the endometriomas was found to besmaller than 5 cm. There was no significant difference betweenthe endometrioma and the benign cyst group in terms ofmedian NLR values (1.848 and 1.635, respectively, p=0.124).PLR median values were significantly higher in endometriomagroup than in benign cyst group (128.77 and 114.69,respectively, p=0.015). NLR ratio was found to be statisticallysignificantly higher in bilateral endometriomas compared tounilaterals.Conclusion: Although NLR was not found to be elevated inpatients with endometrioma, it was found to be affected frombilaterality. PLR was found to be elevated in patients withendometrioma and not affected by the stage of the disease.

Özet

Amaç: Nötrofil/lenfosit oranı (NLR) ve trombosit/ lenfosit oranının (PLR) kronik enflamatuvar bir hastalık olan endometriomada tanı değerinin olup olmadığını değerlendirmektir. Yöntemler: Bu retrospektif, karşılaştırmalı olgu serisine adneksiyel kitle nedeniyle opere edilip patoloji sonucu endometrioma gelen 97 hasta ile kontrol grubu olarak patoloji sonucu benign kist (korpus luteum, seröz kist ya da fonksiyonel kistler) olan 90 hasta dahil edildi. Hastaların preoperatif dönemde hemogram parametrelerinden elde edilen NLR ve PLR değerleri iki grup arasında karşılaştırıldı. Bulgular: Endometrioma ve benign kist grubu yaş ortalamalarında istatistiksel anlamlı fark yoktu (sırasıyla 34,8±8,93 ve 34±8,59, p=0,88). Endometriomaların %14,4’ü (n=14) bilateraldi. Ortalama endometrioma boyutu 6±2,74 cm olarak belirlendi, %27,8’inin (n=27) 5 cm’den daha küçük olduğu saptandı. Endometrioma ile benign kist grubu arasında ortanca NLR değerleri açısından anlamlı bir fark saptanmadı (sırasıyla 1,848 ve 1,635, p=0,124). PLR ortanca değerleri endometriomada benign kiste göre anlamlı yüksek saptandı (sırasıyla; 128,77 ve 114,69, p=0,015). Bilateral endometriomalarda unilaterallere göre NLR oranının istatistiksel olarak anlamlı yüksek olduğu görüldü. Sonuç: NLR’nin endometrioma olgularında yüksek saptanmasa da bilateral olma durumundan etkilendiği görüldü. PLR’nin ise endometriomalı hastalarda yüksek olduğu ve hastalığın evresinden etkilenmediği tespit edildi.

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Cite This Article

AYDIN, D. S. (2022). Diagnostic Performance of Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio in Endometrioma. İstanbul Medical Journal, Cilt: 20 - Sayı: 1, 13–16. https://ajindex.com/articles/551986

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