Journals / İstanbul Medical Journal / 2019 / Cilt: 20 - Sayı: 1

Does Attenuated Mckittrick-Wheelock Syndrome Exists?

Hafif Mckittrick-Wheelock Sendromu Var Olabilir mi?

Pages
78–79
Publication Date
2022-10-19
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case raises the question whetherthere are mild forms of McKittrick-Wheelock syndrome.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:McKittrick-Wheelock syndrome is caused by fluid andelectrolyte hypersecretion from colorectal tumor.
📊
Key Findings & Data:A52-year-old female patient presented with rectal bleedingand hyponatremia (117 mEq/lt sodium) in biochemistry.
💡
Conclusion & Impact:This case raises the question whetherthere are mild forms of McKittrick-Wheelock syndrome.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

McKittrick-Wheelock syndrome is caused by fluid andelectrolyte hypersecretion from colorectal tumor. We presenta patient with large villous adenoma who had hyponatremiaand rectal bleeding and treated with laparoscopic surgery. A52-year-old female patient presented with rectal bleedingand hyponatremia (117 mEq/lt sodium) in biochemistry. Afterelectrolytic replacement therapy and preoperative colonoscopyand magnetic resonance imaging examinations, the patientunderwent laparoscopic surgery and full postoperativerecovery was achieved. This case raises the question whetherthere are mild forms of McKittrick-Wheelock syndrome.

Özet

McKittrick-Wheelock sendromu kolorektal bir tümörün yüksek miktarda sıvı ve elektrolit salgılamasıyla oluşur. Bu yazıda büyük bir villöz adenom nedeniyle hiponatremi ve rektal kanaması olan ve laparoskopik cerrahi ile tedavi edilen bir hastayı bildirmekteyiz. Elli iki yaşında kadın hasta rektal kanama ve hiponatremi (117 mEq/lt) ile başvurdu. Elektrolit replasman tedavisi ile preoperatif kolonoskopi ve manyetik rezonans görüntüleme ardından hastaya laparoskopik cerrahi uygulandı ve postoperatif tam iyileşme sağlandı. Bu olgu McKittrick-Wheelock sendromunun daha hafif formlarının olabileceği sorusunu akla getirmektedir.

🔖

Cite This Article

YILDIZ, B. D., ÖZDEN, S., ER, S., TEZ, M., YÜKSEL, B. C., TİKİCİ, D. (2022). Does Attenuated Mckittrick-Wheelock Syndrome Exists?. İstanbul Medical Journal, Cilt: 20 - Sayı: 1, 78–79. https://ajindex.com/articles/551968

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Babior BM. Villous adenoma of the colon: Study of a patient with severe fluid and electrolyte disturbances. Am J Med 1966; 41: 615-21
  2. Mckittrick Jr, Mueller S, Starr A. Villous adenoma of the colon associated with severe hypopotassemia. AMA Arch Surg 1956; 73: 995-8
  3. Older J, Older P, Colker J, Brown R. Secretory villous adenomas that cause depletion syndrome. Arch Intern Med 1999; 159: 879-80
  4. Targarona EM, Hernandez PM, Balague C, Martinez C, Hernández J, Pulido D, et al. McKittrick-Wheelock syndrome treated by laparoscopy: report of 3 cases. Surg Laparosc Endosc Percutan Tech 2008; 18: 536-8
  5. Watari J, Sakurai J, Morita T, Yamasaki T, Okugawa T, Toyoshima F, et al. A case of Cronkhite-Canada syndrome complicated by McKittrick-Wheelock syndrome associated with advanced villous adenocarcinoma. Gastrointest Endosc 2011; 73: 624-6
  6. Wakeman CJ. Giant villous adenoma presenting as McKittrick–Wheelock syndrome and pseudo-obstruction. Med J Aust 2010; 192: 225-7
  7. Popescu A, Orban-Schiopu A, Becheanu G, Diculescu M. McKittrick-Wheelock syndromea rare cause of acute renal failure. Rom J Gastroenterol 2005; 14: 63-6
  8. Ohara Y, Toyonaga T, Watanabe D, Hoshi N, Adachi S, Yoshizaki T, et al. Electrolyte depletion syndrome (McKittrick–Wheelock syndrome) successfully treated by endoscopic submucosal dissection. Clin J Gastroenterol 2015; 8: 280-4
  9. Kagan MD, Schmidt K, Sangha G. Indomethacin therapy effective in a patient with depletion syndrome from secretory villous adenoma. BMJ Case Rep 2017; 2017. pii: bcr2016217211. 10. van der Pool AEM, de Graaf EJR, Vermaas M, Barendse RM, Doornebosch PG. McKittrick Wheelock Syndrome Treated by Transanal Minimally Invasive Surgery: A Single-Center Experience and Review of the Literature. J Laparoendosc Adv Surg Tech A 2018; 28: 204-8.