Journals / İstanbul Medical Journal / 2020 / Cilt: 21 - Sayı: 4

Assessment of Bone Mineral Density in Patients with Incidental Parathyroidectomy during Thyroidectomy

Tiroidektomi Yapılan Hastalarda İnsidental Paratiroidektominin Kemik Mineral Yoğunluğuna Etkisi

Pages
320–326
Publication Date
2022-10-19
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

After the surgery, the patients hadno harmful effects on BMD and FRAX fracture risk

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Thyroid surgery for benign and malign diseasesis one of the most common procedures performed in surgicalpractice.
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Key Findings & Data:Complication rates are higher in malignant andinflammatory diseases, recurrent surgeries and in hyperthyroidpatients.
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Conclusion & Impact:After the surgery, the patients hadno harmful effects on BMD and FRAX fracture risk
🔬Design:Review & Systematic Survey
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Abstract

Introduction: Thyroid surgery for benign and malign diseasesis one of the most common procedures performed in surgicalpractice. Complication rates are higher in malignant andinflammatory diseases, recurrent surgeries and in hyperthyroidpatients. Hypocalcemia is one of these complications. Thereare many studies investigating the effect of incidentalparathyroid tissue removal on hypocalcemia in thyroidectomyoperations and investigating the risk factors for incidentalparathyroidectomy. However, there are no studies investigatingthe effect on bone mineral density (BMD). In our study, weaimed to reveal the effect of incidental parathyroidectomyduring total thyroidectomy (TT) on BMD and osteoporosis.Methods: Between January 2013 and December 2016,pathology reports of 983 patients who underwent TT,completion thyroidectomy, TT + central neck dissection,TT + functional neck dissection, TT + modified radical neckdissection were retrospectively reviewed.Seventy-two female patients with incidental parathyroid tissuewere included in the study. Demographic information, postoperative biochemical values (calcium, albumin, parathyroidhormone, vitamin D, phosphorus, alkaline phosphatase),BMD, The World Health Organization Frakture Risk AssessmentTool (FRAX) fracture risks were recorded and the relationshipbetween them was evaluated.Results: Patients were divided into three groups accordingto BMD: normal, osteopenic and osteoporotic. Patients inmenopause and patients older than 45-years were morein osteopenic and osteoporotic group. Patients undergoingextended surgery had more parathyroids removed. There wasno correlation between the number of parathyroid glandsremoved and hypocalcemia. After the surgery, the patients hadno harmful effects on BMD and FRAX fracture risk

Özet

Amaç: Benign ve malign hastalıklar için uygulanan tiroid cerrahisi, cerrahi pratiğinde en sık yapılan girişimler arasındadır. Malign hastalıklar, enflamatuvar hastalıklar, tekrarlayan cerrahiler ve hipertiroidili hastalarda komplikasyon oranları daha fazladır. Bu komplikasyonların başında hipokalsemi gelmektedir. Litaratürde tiroidektomi ameliyatlarında insidental paratiroid dokusu çıkarılmasının hipokalsemi üzerine etkisini araştıran ve insidental paratiroidektomiye neden olan risk faktörlerini araştıran pek çok çalışma mevcuttur. Ancak kemik mineral yoğunluğuna (KMY) etkisini araştıran çalışmalar yoktur. Çalışmamızda, total tiroidektomi (TT) esnasında insidental paratiroidektominin KMY’ye ve osteoporoz üzerine etkisini ortaya çıkarmaktır. Yöntemler: Ocak 2013 ile Aralık 2016 tarihleri arasında multinodüler guatr, graves, toksik multinodüler guatr, malignite tanılarıyla TT, tamamlayıcı tiroidektomi, TT + santral boyun diseksiyonu, TT + fonksiyonel boyun diseksiyonu, TT + modifiye radikal boyun diseksiyonu ameliyatı yapılan 983 hastanın patoloji raporları retrospektif olarak incelendi. İnsidental paratiroid dokusu saptanan 72 kadın hasta çalışmaya dahil edildi. Hastaların demografik bilgileri, post-operatif biyokimyasal değerleri (kalsiyum, albümin, parathormon, D vitamini, fosfor, alkalen fosfataz), KMY, Dünya Sağlık Örgütü Kırılma Riski Değerlendirme Aracı (FRAX) fraktü riskleri kaydedilerek aralarındaki ilişki değerlendirildi. Bulgular: Hastalar KMY’ye göre normal, osteopenik ve osteoporotik olmak üzere üç gruba ayrıldı. Menopoz ve 45 yaşın üzerinde olan hastalar osteopenik ve osteoporotik grupta daha fazlaydı. Genişletilmiş cerrahi uygulanan hastalardadaha fazla sayıda paratiroid çıkarılmıştı. Çıkarılan paratiroid sayısıyla hipokalsemi arasında bağlantı saptanmadı. Sonuç: Çalışmamızda, bir veya iki paratiroid bezinin çıkartılmasının KMY üzerine herhangi bir etkisi saptanmadı.

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Cite This Article

DURAL, A. C., AKARSU, C., KARABULUT, M., ŞAHBAZ, N. A., GÜZEY, D., ÖZBÖLÜK, G., ÇABUK, F. K., DAĞANŞEN, S. Ç., ALTINAY, S. (2022). Assessment of Bone Mineral Density in Patients with Incidental Parathyroidectomy during Thyroidectomy. İstanbul Medical Journal, Cilt: 21 - Sayı: 4, 320–326. https://ajindex.com/articles/551891

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