Serum Ischaemia-modified Albumin Concentration in Hyperemesis Gravidarum

Serum IMA levelswere assessed by the enzyme-linked immunosorbent assay(ELISA) method.Results: Serum IMA levels were higher in the HEG group thanthe control group (HEG: 8.2±0.2 ng/mL, control: 6.9±0.3 ng/mL, p

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: The role of oxidative stress in the pathogenesisof hyperemesis gravidarum (HEG) has been demonstratedin a lot of studies.

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Key Findings & Data:The present study aimed to compare theischaemia-modified albumin (IMA) serum levels of patientsdiagnosed with HEG with healthy pregnant women, and toinvestigate whether oxidative stress caused increased serumIMA in HEG.Methods: Pregnant women were classified into a groupdiagnosed with HEG (n=45) and an age- and body mass indexmatched control group without HEG (n=45).

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Conclusion & Impact:Serum IMA levelswere assessed by the enzyme-linked immunosorbent assay(ELISA) method.Results: Serum IMA levels were higher in the HEG group thanthe control group (HEG: 8.2±0.2 ng/mL, control: 6.9±0.3 ng/mL, p

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Introduction: The role of oxidative stress in the pathogenesisof hyperemesis gravidarum (HEG) has been demonstratedin a lot of studies. The present study aimed to compare theischaemia-modified albumin (IMA) serum levels of patientsdiagnosed with HEG with healthy pregnant women, and toinvestigate whether oxidative stress caused increased serumIMA in HEG.Methods: Pregnant women were classified into a groupdiagnosed with HEG (n=45) and an age- and body mass indexmatched control group without HEG (n=45). Serum IMA levelswere assessed by the enzyme-linked immunosorbent assay(ELISA) method.Results: Serum IMA levels were higher in the HEG group thanthe control group (HEG: 8.2±0.2 ng/mL, control: 6.9±0.3 ng/mL, p

Özet

Amaç: Birçok çalışmada hiperemezis gravidarumun (HEG) patogenezinde oksidatif stresin katkısı gösterilmiştir. Bu çalışmada, HEG tanısı konulan hastalarla sağlıklı gebe kadınların serum iskemi modifiye albümin (İMA) düzeylerini karşılaştırmak ve oksidatif stres belirteci olan İMA’nın HEG’de artıp artmadığının araştırılması amaçlanmıştır. Yöntemler: Yaş ve vücut kitle indeksine göre eşleştirilmiş hastalar, HEG tanısı alanlar (n=45) ve sağlıklı gebe kontrol grubu (n=45) olarak ikiye ayrıldı. Serum İMA düzeyleri, her bir katılımcı için enzim bağlı immün assay (ELISA) yöntemi ile analiz edildi. Bulgular: Serum İMA düzeyleri HEG grubunda kontrol grubuna göre daha yüksekti (sırasıyla HEG grubu 8,2±0,2 ng/mL, kontrol grubu 6,9±0,3 ng/mL, p

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Cite This Article

ŞAHİN, D., YAMAN, S., AYHAN, S., TULMAÇ, Ö. B., ÇANDAR, T., TOKMAK, A. (2022). Serum Ischaemia-modified Albumin Concentration in Hyperemesis Gravidarum. İstanbul Medical Journal, Cilt: 21 - Sayı: 4, 297–300. https://ajindex.com/articles/551890

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