SavedAdd your journal

Journals / İstanbul Kuzey Klinikleri / 2015 / Cilt: 2 - Sayı: 3

Pustular eruption induced by etanercept in a patient with ankylosing spondylitis: a rare side effect

Emine Tugba ALATAS
Yelda DERE
Gursoy DOGAN
Hilal Semra CELEBİ
Asude KARA
Pages
231–235
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Herein, we report a case of generalized pustular eruption due to etanercept therapy in an ankylosing spondylitis patient and review pustular diseases.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Etanercept is a tumor necrosis factor alpha (TNF-α) antagonist with anti-inflammatory effects.
📊
Key Findings & Data:It is used in the treatment of dermatologic and rheumatologic diseases such as rheumatoid arthritis, polyarticular juvenile rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis.
💡
Conclusion & Impact:Herein, we report a case of generalized pustular eruption due to etanercept therapy in an ankylosing spondylitis patient and review pustular diseases.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Etanercept is a tumor necrosis factor alpha (TNF-α) antagonist with anti-inflammatory effects. It is used in the treatment of dermatologic and rheumatologic diseases such as rheumatoid arthritis, polyarticular juvenile rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. However, etanercept has various cutaneous and systemic side effects. Herein, we report a case of generalized pustular eruption due to etanercept therapy in an ankylosing spondylitis patient and review pustular diseases.

🔖

Cite This Article

ALATAS, E. T., DERE, Y., DOGAN, G., CELEBİ, H. S., KARA, A. (2022). Pustular eruption induced by etanercept in a patient with ankylosing spondylitis: a rare side effect. İstanbul Kuzey Klinikleri, Cilt: 2 - Sayı: 3, 231–235. https://ajindex.com/articles/551684

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Akdeniz N, Çalka Ö, Bilgili SG. Biyolojik ajanlar. In: Tüzün Y, Serdaroğlu S, Erdem C, Özpoyraz M, Önder M, Öztürkcan S, editor. Dermatolojide tedavi. İstanbul: Nobel Tıp Kitapevleri 2010. p. 927–41
  2. Adams BB, Mutasim DF. Pustular eruption induced by olanzapine, a novel antipsychotic agent. J Am Acad Dermatol 1999;41(5 Pt 2):851–3
  3. Mengesha YM, Bennett ML. Pustular skin disorders: diagnosis and treatment. Am J Clin Dermatol 2002;3:389–400
  4. Vasconcelos LMF, Teixeira FM, Francelino EV, Almeida TLP, Chagas LB, Valença JT, et al. Acute generalized exanthematous pustulosis in a 51-year- old patient under etanercept treatment for psoriasis. J Pharmacovigilance 2014;2:120
  5. Weinblatt ME, Kremer JM, Bankhurst AD, Bulpitt KJ, Fleischmann RM, Fox RI, et al. A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. N Engl J Med 1999;340:253–9
  6. Collamer AN, Guerrero KT, Henning JS, Battafarano DF. Psoriatic skin lesions induced by tumor necrosis factor antagonist therapy: a literature review and potential mechanisms of action. Arthritis Rheum 2008;59:996–1001
  7. Kavala M, Zindancı I, Türkoglu Z, Can B, Kocatürk E, Senol S, et al. Acute generalized exanthematous pustulosis induced by etanercept: another dermatologic adverse effect. Case Rep Dermatol Med 2013;2013:601412
  8. Revuz J, Valeyrie-Allanore L. Drug Reactions. In: Bolognia JL, editor. Dermatology 2012;21:335–56
  9. Cohen JD, Bournerias I, Buffard V, Paufler A, Chevalier X, Bagot M, et al. Psoriasis induced by tumor necrosis factor-alpha antagonist therapy: a case series. J Rheumatol 2007;34:380–5
  10. Joyau C, Veyrac G, Dixneuf V, Jolliet P. Anti-tumour necrosis factor alpha therapy and increased risk of de novo psoriasis: is it really a paradoxical side effect? Clin Exp Rheumatol 2012;30:700–6
  11. Lai-Cheong J, Warren R, Bucknall R, Parslew R. Etanerceptinduced dermatitis in a patient with rheumatoid arthritis. J Eur Acad Dermatol Venereol 2006;20:614–5. 12. de Gannes GC, Ghoreishi M, Pope J, Russell A, Bell D, Adams S, et al. Psoriasis and pustular dermatitis triggered by TNF- {alpha} inhibitors in patients with rheumatologic conditions. Arch Dermatol 2007;143:223–31
  12. Dimitrova V, Yordanova I, Pavlova V, Valtchev V, Gospodinov D, Parashkevova B, et al. Keratoderma blenorrhagicum in a patient with Reiter syndrome. J of IMAB 2008;14:68–71
  13. İlaç ve diğer tedavi reaksiyonları. In: Baykal C, editö