Journals / İstanbul Kuzey Klinikleri / 2016 / Cilt: 3 - Sayı: 1

Blink reflex in migraine headache

Pages
1–8
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was no statistically significant correlation between the recorded latencies and gender, attack duration, attack frequency and migraine type (p>0.05).CONCLUSION: Results of BR test in the present study are thought to point to a dysfunction in brainstem and trigeminovascular connections of patients with migraine headache and support the trigeminovascular theory of migraine.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:OBJECTIVE: Activation of trigeminovascular system is thought to play an important role in migraine pathogenesis.
📊
Key Findings & Data:Latencies recorded in BR test were evaluated to examine neurophysiological changes that occur in migraine patients.METHODS: A total of 40 patients diagnosed with migraine (9 with aura and 31 without aura) according to the International Headache Society (IHS) International Classification of Headache Disorders, 2nd edition, and 30 healthy control patients were assessed using BR test.
💡
Conclusion & Impact:There was no statistically significant correlation between the recorded latencies and gender, attack duration, attack frequency and migraine type (p>0.05).CONCLUSION: Results of BR test in the present study are thought to point to a dysfunction in brainstem and trigeminovascular connections of patients with migraine headache and support the trigeminovascular theory of migraine.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Activation of trigeminovascular system is thought to play an important role in migraine pathogenesis. Blink reflex (BR) test is an easy method to study the trigeminal system. Latencies recorded in BR test were evaluated to examine neurophysiological changes that occur in migraine patients.METHODS: A total of 40 patients diagnosed with migraine (9 with aura and 31 without aura) according to the International Headache Society (IHS) International Classification of Headache Disorders, 2nd edition, and 30 healthy control patients were assessed using BR test. Supraorbital nerve was stimulated on each side, and unilateral right early component (R1), and bilateral late component (R2) latencies were evaluated.RESULTS: Significantly longer latency values were recorded on both right and left sides (RR1 and LR1) as well as both ipsilateral and contralateral R2 on the left side (LR2i and LR2c) in the migraine group compared to the control group. Longer RR1 and LR1 latencies were found in migraneous patients who had an attack at the time of study (p0.05). But significantly longer R1 and R2i latencies were found at the symptomatic side of migraneous patients examined in the ictal period (p=0.037 and p=0.028 respectively). There was no statistically significant correlation between the recorded latencies and gender, attack duration, attack frequency and migraine type (p>0.05).CONCLUSION: Results of BR test in the present study are thought to point to a dysfunction in brainstem and trigeminovascular connections of patients with migraine headache and support the trigeminovascular theory of migraine.

🔖

Cite This Article

UNAL, Z., KOCER, A., TANRİDAG, T., BOYLU, E., MAYDA, F. D., US, O. (2022). Blink reflex in migraine headache. İstanbul Kuzey Klinikleri, Cilt: 3 - Sayı: 1, 1–8. https://ajindex.com/articles/551638

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Aguggia M. Allodynia and migraine. Neurol Sci 2012;33:9-11.
  2. De Marinis M, Pujia A, Colaizzo E, Accornero N. The blink re- flex in chronic migraine. Clin Neurophysiol 2007;118:457-63.
  3. Dodick D, Silberstein S. Central sensitization theory of mi- graine: clinical implications. Headache 2006;46:182-91.
  4. Bolay H, Reuter U, Dunn A, Huang Z, Boas D, Moskowitz A. İntrinsic brain activity triggers trigeminal meningeal afferents in a migraine model. Nature Medicine 2002;8:136-42. Moskowitz MA. The neurobiology of vascular head pain Ann Neurol 1984;16:157-68.
  5. Goadsby PJ, Edvinsson L. The trigeminovascular system and mi- graine: studies characterizing cerebrovascular and neuropeptide changes seen in humans and cats. Ann Neurol 1993;33:48-56.
  6. Burstein R, Yarnitsky D, Goor-Aryeh I, Ransil BJ, Bajwa ZH. An association between migraine and cutaneous allodynia. Ann Neurol 2000;47:614-24.
  7. Ellrich J, Andersen OK, Messlinger K, Arendt-Nielsen L. Con- vergence of meningeal and facial afferents onto trigeminal brain- stem neurons: an electrophysiological study in rat and man. Pain 1999; 82:229-37.
  8. Magis D, Ambrossini A, Bendtsen L, Ertas M, Kaube H, Schoene J. Eurohead Project. Evaluation and proposal for opti- malization of neurophysiological tests in migraine: part 1-elec- trophysiological tests. Cephalalgia 2007;27:1323-38.
  9. Yıldırım G, Sayın R, Cögen EE, Odabas FO, Tombul T. Ran- domised, controlled blink reflex in patients with migraine and tension type headache. J Pak Med Assoc 2011;61:978-82. Miskov S. Neurophysiological methods in headache diagnosis. Acta Med Croatica 2008;62:189-96.
  10. Zdunska A, Cegielska J, Kochanowski J. Variability of the blink reflex in patients with migraine. Neurol Neurochir Pol 2013;47:352-6.
  11. Magis D, Vigano A, Sava S, d'Elia TS, Schoenen J, Coppola G. Pearls and pitfalls: electrophysiology for primary headaches. Cephalalgia 2013;33:526-39.
  12. Sohn JH, Choi HC, Kim CH. Differences between episodic and chronic tension-type headaches in nociceptive-specific trigemi- nal pathways. Cephalalgia 2013;33:330-9.
  13. Shahani BT, Young RR. Human orbicularis oculi reflexes. Neu- rology 1972;22:149-54.
  14. Nardone R, Tezzon F. Brainstem reflexes in migraine patients. In: Clarke LB, editor. Migraine disorders research trends. New York: Nova Science Publishers; 2007. p. 183-208.
  15. Bahra A, Matharu MS, Buchel C, Frackowiak RS, Goadsby PJ. Brainstem activation specific to migraine headache. Lancet 2001;357:1016-18.
  16. Weiller C, May A, Limmroth V, et al.: Brainstem activation in s