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Journals / İstanbul Kuzey Klinikleri / 2016 / Cilt: 3 - Sayı: 1

Relationship between newborn craniotabes and vitamin D status

Mehmet KARACİ
Adem YASAR
Berrak GUVEN
Makbule ERCAN
Gamze OZGURHAN
Mustafa OZCETİN
Pages
15–21
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, measures to prevent maternal vitamin D deficiency should be strengthened.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:OBJECTIVE: In recent studies, vitamin D deficiency during pregnancy and early infancy has been reported to predispose children to many chronic diseases, except those of the skeletal system.
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Key Findings & Data:METHODS: A total of 150 healthy newborns with a weight of over 2000 g were included.
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Conclusion & Impact:Therefore, measures to prevent maternal vitamin D deficiency should be strengthened.
🔬Design:Research Article
📍Scope:2000 Verileri
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: In recent studies, vitamin D deficiency during pregnancy and early infancy has been reported to predispose children to many chronic diseases, except those of the skeletal system. The aim of this study was to investigate whether craniotabes in otherwise healthy newborns is physiological, its relationship to vitamin D deficiency and whether or not it requires treatment. METHODS: A total of 150 healthy newborns with a weight of over 2000 g were included. Newborns were divided into two groups during postnatal discharge (1-3.'s day): those with and without craniotabes. The 25-hydroxy (OH) vitamin D levels of the newborns' mothers were measured, and all infants were re-evaluated for craniotabes, as well as tested to determine levels of serum calcium (Ca), phosphorus (P), alkaline phosphatase (ALP), parathyroid hormone (PTH) and 25(OH) vitamin D, urine calcium and creatinine. RESULTS: Craniotabes was present in 45 (30%) of newborns enrolled in the study. Craniotabes of the newborns born during the winter months was significantly higher. PTH level was significantly higher in 1-month-old newborns with craniotabes than those without craniotabes. No relationship was observed between diet and craniotabes, but in exclusively breastfed infants, vitamin D level was statistically significantly lower. No statistically significant difference was found in the occurrence of craniotabes in newborns with or without vitamin D support.CONCLUSION: The relationship between newborn craniotabes and maternal vitamin D deficiency is not clear. However, the present study illustrates that maternal vitamin D deficiency is still a major problem. Therefore, measures to prevent maternal vitamin D deficiency should be strengthened.

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Cite This Article

KARACİ, M., YASAR, A., GUVEN, B., ERCAN, M., OZGURHAN, G., OZCETİN, M. (2022). Relationship between newborn craniotabes and vitamin D status. İstanbul Kuzey Klinikleri, Cilt: 3 - Sayı: 1, 15–21. https://ajindex.com/articles/551617

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References (13)

  1. Fox GN, Maier MK. Neonatal craniotabes. Am Fam Physician 1984;30:149-51.
  2. Otto FM, Hesse V. Craniotabes, craniomalacia (Wieland) and active ricketts in infants. [Article in German] Kinderarztl Prax 1990;58:179-83. [Abstract] Vitamin D supplement in early childhood and risk for Type I (insulin-dependent) diabetes mellitus. The EURODIAB Sub- study 2 Study Group. Diabetologia 1999;42:51-4.
  3. Hyppönen E, Läärä E, Reunanen A, Järvelin MR, Virtanen SM. Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. Lancet 2001;358:1500-3. Ward LM. Vitamin D deficiency in the 21st century: a persis- tent problem among Canadian infants and mothers. CMAJ 2005;172:769-70. American Academy of Pediatrics. Clinical Report: Prevention of Rickets and Vitamin D Deficiency: New Guidelines for Vitamin D. Pediatrics 2003;111:908-11.
  4. Pehlivan I, Hatun S, Aydoğan M, Babaoğlu K, Gökalp AS. Ma- ternal vitamin D deficiency and vitamin D supplementation in healthy infants. Turk J Pediatr 2003;45:315-20.
  5. Javaid MK, Crozier SR, Harvey NC, Gale CR, Dennison EM, Boucher BJ, et al. Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a longitudinal study. Lancet 2006;367:36-43.
  6. Camargo Jr CA, Rifas-Shiman SL, Litonjua AA, Edwards JWR, Weiss ST, Gold DR, et al. Prospective study of maternal intake of vitamin D during pregnancy and risk of wheezing illness in chil- dren at age 2 years. J Allergy Clin Immunol 2006;117(3):721-2.
  7. Najada AS, Habashneh MS, Khader M. The frequency of nu- tritional rickets among hospitalized infants and its relation to respiratory diseases. J Trop Pediatr 2004;50:364-8.
  8. Yorifuji J, Yorifuji T, Tachibana K, Nagai S, Kawai M, Mo- moi T, et al. Craniotabes in normal newborns: the earliest sign of subclinical vitamin D deficiency. J Clin Endocrinol Metab 2008;93:1784-8.
  9. Şimşek E, Kocabay K. Calcium, phosphorus and magnesium ho- meostasis. Türkiye Klinikleri J Pediatr 2002;11:211-20.
  10. Güven A, Ecevit A, Tarcan A, Tarcan A, Özbek N. Cord blood vitamin D levels. Çocuk Sağ Hast Derg 2011;54:55-61.
  11. Sachan A, Gupta R, Das V, Agarwal A, Awasthi PK, Bhatia V. High prevalence of vitamin D deficiency among pregnant women and their newborns in northern India. Am J Clin Nutr 2005;81:1060-4.
  12. Bodnar LM, Simhan HN, Powers RW, Frank MP, Cooperstein E, Roberts JM. High prevalence of vitamin D insufficiency in black and white pregnant women residing in the northern Unit- ed States and their neonates. J Nutr 2007;137:447-52.
  13. Hollis BW, Pittard WB 3rd.