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Journals / İstanbul Kuzey Klinikleri / 2017 / Cilt: 4 - Sayı: 3

Impact of insulin resistance and obesity on intracytoplasmic sperm injection outcomes in young women with polycystıc ovary syndrome

Fisun VURAL
Birol VURAL
Yigit CAKİROGLU
Sule Yildirim KOPUK
Emek DOGER
Pages
218–224
Publication Date
2022-10-18
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Neither BMI nor IR had an independent effect on ovarian response and IVF success in young women with PCOS.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:OBJECTIVE: To examine effects of body mass index (BMI) and insulin resistance (IR) on the in vitro fertilization (IVF) outcomes in women with polycystic ovary syndrome (PCOS).
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Key Findings & Data:METHODS: A total of 106 women with PCOS who underwent intracytoplasmic sperm injection were investigated.
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Conclusion & Impact:Neither BMI nor IR had an independent effect on ovarian response and IVF success in young women with PCOS.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: To examine effects of body mass index (BMI) and insulin resistance (IR) on the in vitro fertilization (IVF) outcomes in women with polycystic ovary syndrome (PCOS). METHODS: A total of 106 women with PCOS who underwent intracytoplasmic sperm injection were investigated. The patients were stratified into groups according to their BMI [healthy weight: BMI 2.5). The main outcome measures were reproductive and IVF outcomes with respect to BMI and IR.RESULTS: The basal hormonal evaluations, such as follicle-stimulating hormone (FSH), luteinizing hormone (LH), LH/FSH, estradiol, testosterone, DHEAS, AMH, and antral follicle counts, were similar between the groups of BMI and IR. The number of retrieved oocytes, MII oocytes, embryo counts, and fertilization and pregnancy rates were similar between lean and overweight/obese PCOS with and without IR. Even though pregnancy and delivery rates per started cycle and embryo transfer were higher in healthy-weight women with PCOS than in overweight/obese patients, it did not reach statistical significance. CONCLUSION: Reproductive outcomes in women with PCOS according to BMI and IR were similar. Neither BMI nor IR had an independent effect on ovarian response and IVF success in young women with PCOS.

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Cite This Article

VURAL, F., VURAL, B., CAKİROGLU, Y., KOPUK, S. Y., DOGER, E. (2022). Impact of insulin resistance and obesity on intracytoplasmic sperm injection outcomes in young women with polycystıc ovary syndrome. İstanbul Kuzey Klinikleri, Cilt: 4 - Sayı: 3, 218–224. https://ajindex.com/articles/551593

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