AI Summary & Key Takeaways
AI InsightHowever, these findings were not statistically significant.CONCLUSION: Further controlled studies with large sample size are needed to determine the characteristic NVC findings ofDR in patients with type 2 DM.
📌 3 Key Takeaways
Abstract
OBJECTIVE: Diabetes mellitus (DM) is a chronic hyperglycemic state and is associated with microvascular structural alterations. This study aimed to investigate the diameters of capillary loops and morphostructural changes using nailfold videocapillaroscopy (NVC) in patients with type 2 DM with and without diabetic retinopathy (DR).METHODS: This cross-sectional, single-center study was conducted in patients with type 2 DM who were followed in outpatient clinics of ophthalmology and internal medicine. General demographic data were collected from patients. An ophthalmologist examined all patients in terms of DR. A rheumatologist blinded to the clinical data performed NVC. The diametersof apical, arterial, and venous loop of capillaries were measured, and the microvascular changes of capillaries were scored.RESULTS: In this study, 44 patients with type 2 DM with DR (47.7% males) and 20 patients with type 2 DM without DR(55% males) were included. In our study, patients with type 2 DM with DR had more frequent capillary hemorrhage, morefrequent ectasia, more frequent giant capillary, and more frequent neo-angiogenesis than patients with type 2 DM withoutDR. However, these findings were not statistically significant.CONCLUSION: Further controlled studies with large sample size are needed to determine the characteristic NVC findings ofDR in patients with type 2 DM.