SavedAdd your journal

Journals / İstanbul Kuzey Klinikleri / 2020 / Cilt: 7 - Sayı: 6

Retrospective evaluation of the effects of sugammadexand neostigmine on the IgE and eosinophil cationicprotein in morbid obese patients

Özkan GÖRGÜLÜ
Mehmet Nuri KOŞAR
Pages
572–578
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Patient data were recorded, including patient preoperative demographics (age, gender) and preoperative and postoperative (12 hours later) levels of total IgE and ECP (Eosinophil cationic protein) levels.RESULTS: There was not a significant change in the total IgE levels in Group S or Group N (p>0.05); however, the levels of ECP significantly decreased in both groups (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:OBJECTIVE: This study was designed to show that allergic reactions with gamma cyclodextrin-related caused by sugammadex are not anaphylaxis but an anaphylactoid reaction.METHODS: In this retrospective study, 83 morbidly obese patients, who underwent elective laparoscopic sleeve gastrectomy operation, were included.
📊
Key Findings & Data:Patient data were obtained from patient files and electronic health records system (SARUS).
💡
Conclusion & Impact:Patient data were recorded, including patient preoperative demographics (age, gender) and preoperative and postoperative (12 hours later) levels of total IgE and ECP (Eosinophil cationic protein) levels.RESULTS: There was not a significant change in the total IgE levels in Group S or Group N (p>0.05); however, the levels of ECP significantly decreased in both groups (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: This study was designed to show that allergic reactions with gamma cyclodextrin-related caused by sugammadex are not anaphylaxis but an anaphylactoid reaction.METHODS: In this retrospective study, 83 morbidly obese patients, who underwent elective laparoscopic sleeve gastrectomy operation, were included. Patient data were obtained from patient files and electronic health records system (SARUS). The patients were divided into two groups as sugammadex (Group S) and neostigmine (Group N). Patient data were recorded, including patient preoperative demographics (age, gender) and preoperative and postoperative (12 hours later) levels of total IgE and ECP (Eosinophil cationic protein) levels.RESULTS: There was not a significant change in the total IgE levels in Group S or Group N (p>0.05); however, the levels of ECP significantly decreased in both groups (p

🔖

Cite This Article

GÖRGÜLÜ, Ö., KOŞAR, M. N. (2022). Retrospective evaluation of the effects of sugammadexand neostigmine on the IgE and eosinophil cationicprotein in morbid obese patients. İstanbul Kuzey Klinikleri, Cilt: 7 - Sayı: 6, 572–578. https://ajindex.com/articles/551357

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. O’Donnell R, Hammond J, Soltanifar S. A confirmed case of sugammadex-induced anaphylaxis in a UK hospital. BMJ Case Rep 2017;2017:bcr2017220197
  2. Sharma S, Tomar S, Dharne M, Ganesan V, Smith A, Yang Y, et al. Deletion of ΔdblGata motif leads to increased predisposition and severity of IgE-mediated food-induced anaphylaxis response. PLoS One 2019;14:e0219375
  3. Tobias JD. Current evidence for the use of sugammadex in children. Paediatr Anaesth 2017;27:118–25
  4. Takazawa T, Mitsuhata H, Mertes PM. Sugammadex and rocuronium-induced anaphylaxis. J Anesth 2016;30:290–7
  5. Akha AS, Rosa J 3rd, Jahr JS, Li A, Kiai K. Sugammadex: cyclodextrins, development of selective binding agents, pharmacology, clinical development, and future directions. Anesthesiol Clin 2010;28:691–708
  6. Szente L, Szejtli J. Cyclodextrins as food ingredients. Food Sci Technol 2004;15:137–42
  7. Hotta E, Tamagawa-Mineoka R, Masuda K, Taura M, Nakagawa Y, Kanehisa F, et al. Anaphylaxis caused by γ-cyclodextrin in sugammadex. Allergol Int 2016;65:356–8
  8. Min KC, Woo T, Assaid C, McCrea J, Gurner DM, Sisk CM, et al. Incidence of hypersensitivity and anaphylaxis with sugammadex. J Clin Anesth 2018;47:67–73
  9. Mineeva EE, Antonyuk MV, Yurenko AV, Gvozdenko TA. Functional state of the small airways in patients with bronchial asthma associated with obesity. Ter Arkh 2019;91:60–3
  10. De La Cruz I, Errando C, Calaforra S. Treatment of Anaphylaxis to Rocuronium with Sugammadex: A Case Report with Bronchospasm as the Only Symptom. Turk J Anaesthesiol Reanim 2019;47:69–72
  11. Shin YH, Kim HS, Lee EK, Kim YJ, Lee HS, Jang PS, et al. Eosinophil-related markers and total immunoglobulin E as a predictive marker for antibiotic response in chronic rhinosinusitis. Ann Saudi Med 2015;35:312–7
  12. Guo CL, Sun XM, Wang XW, Guo Q. Serum Eosinophil Cationic Protein Is a Useful Marker for Assessing the Efficacy of Inhaled Corticosteroid Therapy in Children with Bronchial Asthma. Tohoku J Exp Med 2017;242:263–71
  13. Vaillant AAJ, Zito PM. Immediate Hypersensitivity Reactions. StatPearls Publishing LLC; 2019
  14. Kırgezen T, Server EA, Turanoğlu FS, Yiğit Ö, Uzun H, Durmuş S. Salivary Eosinophil Cationic Protein in Allergic Rhinitis. Turk Arch Otorhinolaryngol 2019;57:91–4
  15. Jiang XG, Yang XD, Lv Z, Zhuang PH. Elevated serum levels of TNF-α, IL-8, and ECP can be involved in the development and progression of bronchial asthma. J Asthma 2018;55:111-8
  16. Lodin K, Lekander M, Syk J, Alving K, Andreas