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Journals / İstanbul Kuzey Klinikleri / 2020 / Cilt: 7 - Sayı: 5

Serum prolidase activity in patients with cardiac syndrome X

Orkide KUTLU
Ömer Faruk BAYCAN
Asuman GEDİKBAŞI
Şeref KUL
Bulent DEMİR
Adem ATICI
Mehmet KOÇAK
Gonul AÇIKSARI
Turgut UYGUN
Pages
471–477
Publication Date
2022-10-18
DOI
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Ltd, China).Results: Mean prolidase activity was 898.8±639.1 mU/mL in the CSX group and 434.1±289.8 mU/mL in the control group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Although the underlying mechanism is not yet fully understood, Cardiac Syndrome X (CSX) is defined as microvascular dysfunction.
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Key Findings & Data:Increased serum prolidase activity (SPA) has been shown to correlate with collagen turnover.
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Conclusion & Impact:Ltd, China).Results: Mean prolidase activity was 898.8±639.1 mU/mL in the CSX group and 434.1±289.8 mU/mL in the control group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Although the underlying mechanism is not yet fully understood, Cardiac Syndrome X (CSX) is defined as microvascular dysfunction. Prolidase plays a role in collagen synthesis. Increased serum prolidase activity (SPA) has been shown to correlate with collagen turnover. Augmented collagen turn-over may be associated with vascular fibrosis and microvascular dysfunction. In this study, we assessed whether there was a correlation between CXS and prolidase activity.Methods: This case-control study included 45 consecutive CSX patients (mean age 50.7±6.5 years, 27 women) and 40 healthy controls (mean age 51.2±6.5 years, 25 women). Prolidase activity was determined with the Human Xaa-Pro Dipeptidase/Prolidase enzyme-linked immunosorbent assay kit (Cusabio Biotech Co. Ltd, China).Results: Mean prolidase activity was 898.8±639.1 mU/mL in the CSX group and 434.1±289.8 mU/mL in the control group (p

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Cite This Article

KUTLU, O., BAYCAN, Ö. F., GEDİKBAŞI, A., KUL, Ş., DEMİR, B., ATICI, A., KOÇAK, M., AÇIKSARI, G., UYGUN, T. (2022). Serum prolidase activity in patients with cardiac syndrome X. İstanbul Kuzey Klinikleri, Cilt: 7 - Sayı: 5, 471–477. https://ajindex.com/articles/551354

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