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Journals / İstanbul Kuzey Klinikleri / 2020 / Cilt: 7 - Sayı: 1

Can the development of atrial fibrillation in patients with ischemic heart failure with low ejection fraction be predicted?

Kubilay ERSELCAN
Aydın AKYÜZ
Niyazi GÜLER
Şeref ALPSOY
Birol TOPÇU
Demet ÖZKARAMANLI GÜR
Şahin TOPUZ
Pages
18–24
Publication Date
2022-10-18
DOI
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⚡ TL;DR(Too Long; Didn't Read)

NT-pro BNP was established as the predictor of PAF (OR=1.23, 95% CI: 1.08–1.42; p=0.001).ROC analysis showed an NT-pro BNP value of 2188 pg/mL as cut-off value with 68% sensitivity and 84% specificity [Areaunder the ROC curve (AUC)=0.826, CI 95%: 0.724–0.927; p

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Our aim is to determine the triggering factors of paroxysmal atrial fibrillation (PAF) in ischemic heart failure(HF) patients with low ejection fraction (EF).METHODS: Sixty patients were included in this study.
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Key Findings & Data:Echocardiography and 24-hours Holter monitoring were performed after measurement of serum NT-pro BNP concentration.
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Conclusion & Impact:NT-pro BNP was established as the predictor of PAF (OR=1.23, 95% CI: 1.08–1.42; p=0.001).ROC analysis showed an NT-pro BNP value of 2188 pg/mL as cut-off value with 68% sensitivity and 84% specificity [Areaunder the ROC curve (AUC)=0.826, CI 95%: 0.724–0.927; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Our aim is to determine the triggering factors of paroxysmal atrial fibrillation (PAF) in ischemic heart failure(HF) patients with low ejection fraction (EF).METHODS: Sixty patients were included in this study. Echocardiography and 24-hours Holter monitoring were performed after measurement of serum NT-pro BNP concentration. The patients were classified into two groups concerning the occurrenceof PAF on Holter recordings. Biochemical and echocardiographic parameters of patients with and without PAF were compared.RESULTS: PAF was detected in 28 (46%) patients. Patients with PAF demonstrated higher NT-pro BNP levels, mitral andaortic regurgitation velocities, E/A, E/E’, pulmonary capillary wedge pressure, pulmonary artery systolic pressure, left atrialvolume and volume indices. NT-pro BNP was established as the predictor of PAF (OR=1.23, 95% CI: 1.08–1.42; p=0.001).ROC analysis showed an NT-pro BNP value of 2188 pg/mL as cut-off value with 68% sensitivity and 84% specificity [Areaunder the ROC curve (AUC)=0.826, CI 95%: 0.724–0.927; p

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Cite This Article

ERSELCAN, K., AKYÜZ, A., GÜLER, N., ALPSOY, Ş., TOPÇU, B., GÜR, D. Ö., TOPUZ, Ş. (2022). Can the development of atrial fibrillation in patients with ischemic heart failure with low ejection fraction be predicted?. İstanbul Kuzey Klinikleri, Cilt: 7 - Sayı: 1, 18–24. https://ajindex.com/articles/551349

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References (9)

  1. Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JGF, Coats AJS, et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J 2016;37:2129–200
  2. Writing Committee Members, Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE Jr, Drazner MH, et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation 2013;128:e240–327
  3. Fuster V, Rydén LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, et al. ACC/AHA/ESC 2006 Guidelines for the Management of Patients with Atrial Fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation): developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society. Circulation 2006;114:e257–354
  4. Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, et al; ESC Scientific Document Group. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Eur Heart J 2016;37:2893–962
  5. Healey JS, Connolly SJ, Gold MR, Israel CW, Van Gelder IC, Capucci A, et al; ASSERT Investigators. Subclinical atrial fibrillation and the risk of stroke. N Engl J Med 2012;366:120–9
  6. Zhang C, Kasner SE. Paroxysmal Atrial Fibrillation in Cryptogenic Stroke: an Overlooked Explanation? Curr Atheroscler Rep 2015;17:66
  7. Benjamin EJ, Levy D, Vaziri SM, D’Agostino RB, Belanger AJ, Wolf PA. Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study. JAMA 1994;271:840–4
  8. Swedberg K, Olsson LG, Charlesworth A, Cleland J, Hanrath P, Komajda M, et al. Prognostic relevance of atrial fibrillation in patients with chronic heart failure on long-term treatment with beta-blockers: results from COMET. Eur Heart J 2005;26:1303–8
  9. Corell P, Gustafsson F, Schou M, Markenvard J, Nielsen T, Hildebrandt P. Prevalence and prognostic significance of atrial fibrillation in outpatients with heart failure due