Journals / İstanbul Kanuni Sultan Süleyman Tıp Dergisi / 2014 / Cilt: 6 - Sayı: 3

Retrospective Analysis of Obstetric and Perinatal Outcomes in Pregnant Women with Epilepsy

Epilepsi Tanılı Gebelerde Obstetrik ve Perinatal Sonuçların Retrospektif Analizi

Pages
127–132
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

They should be informed for the potential risks of epilepsy before becoming pregnant and the necessary changes in treatment should be made during preconceptional period.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The study was undertaken to assess the obstetric and perinatal outcomes of pregnancies complicated by epilepsy which is a common neurologic disorder of pregnancy.Material and Methods: Forty-two pregnant women with a diagnosis of epileptic disorder who delivered at our clinic between January 2009 and December 2013 were included in this study.
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Key Findings & Data:Data including demographic, obstetric and perinatal outcomes of all the pregnant women in this study were obtained from the archives of the hospital and electronic records.Results: The mean maternal age was 28,5±5,1 years.
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Conclusion & Impact:They should be informed for the potential risks of epilepsy before becoming pregnant and the necessary changes in treatment should be made during preconceptional period.
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The study was undertaken to assess the obstetric and perinatal outcomes of pregnancies complicated by epilepsy which is a common neurologic disorder of pregnancy.Material and Methods: Forty-two pregnant women with a diagnosis of epileptic disorder who delivered at our clinic between January 2009 and December 2013 were included in this study. Data including demographic, obstetric and perinatal outcomes of all the pregnant women in this study were obtained from the archives of the hospital and electronic records.Results: The mean maternal age was 28,5±5,1 years. The mean gestational age and fetal weight was 39±1,6 weeks and 3218±477 gr at the time of birth, respectively. Four pregnants (9.5 %) were born before 37. gestational weeks. There were no adverse obstetric outcomes such as preeclampsia, bleeding in pregnancy and excessive postpartum bleeding. Caesarean section rate was 52.8 % in the study group. The preconception counseling rate was 28.6 % in the study group. The most commonly used drug was carbamazepine (30 %). Fourteen (33.3 %) pregnants with epilepsy had a seizure during pregnancy. The most frequent seizures happened during the first trimester (52.6 %). Four (9.5 %) newborns had low 5th minute Apgar score at birth. Major congenital malformations were present in 2 (4.8 %) newborns. Conclusion: Epileptic pregnants carry some risks secondary to the disease and its medical therapy. They should be informed for the potential risks of epilepsy before becoming pregnant and the necessary changes in treatment should be made during preconceptional period.

Özet

ET Amaç: Bu çalışmada, gebeliğe eşlik edebilen nörolojik bir hastalık olan epilepsinin gebelik ve perinatal sonuçlar üzerindeki etkisinin değerlendirilmesi amaçlandı.Gereç ve Yöntem: Ocak 2009 ve Aralık 2013 tarihleri arasında kliniğimizde doğum yapmış 42 epilepsi tanısı olan gebe çalışmaya dahil edildi. Çalışma kapsamına dahil edilen gebelere ait demografik, obstetrik ve perinatal sonuçlarla ilişkili bilgiler, hastanemize ait arşivden ve elektronik kayıtlardan elde edildi.Bulgular: Çalışma grubunda gebelerin yaş ortalaması 28,5±5,1 yıldı. Gebelik haftası ve yenidoğan doğum ağırlığı ortalamaları sırayla 39±1,6 hafta ve 3218±477 g'dı. Dört olgu (% 9,5) erken doğum yaptı. Preeklampsi, gebelikte vajinal kanama ve postpartum aşırı kanama gibi kötü obstetrik sonuçlar izlenmedi. Sezaryen doğum oranı % 52,6 idi. Prekonsepsiyonel danışma alan olgu oranı % 28,6'ydı ve gebelikte en sık kullanılan antiepileptik ilaç karbamazepindi. On dört (% 33,3) olgu gebelik sürecinde epileptik nöbet geçirdi ve nöbetler en sık ilk trimesterde görüldü (% 52,6). Dört yenidoğan bebekte düşük 5. dk. Apgar skoru izlendi. Major konjenital malformasyon 2 (% 4,8) yenidoğanda izlendi.Sonuç: Epilepsili gebeler hem hastalıktan hem de ilaç tedavisinden kaynaklı bazı risklere sahiptirler. Epilepsili gebelerin, epilepsi kaynaklı potansiyel risklerden korunması için gebelikten önce bilgilendirilmeleri ve tedavide gerekli değişikliklerin prekonsepsiyonel dönemde yapılması ile daha iyi sonuçlar elde edilmesi olasıdır.

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Cite This Article

GÖYNÜMER, G., KARADAĞ, C., BOZDAĞ, H., GÜNAY, T., BAYRAK, M. (2022). Retrospective Analysis of Obstetric and Perinatal Outcomes in Pregnant Women with Epilepsy. İstanbul Kanuni Sultan Süleyman Tıp Dergisi, Cilt: 6 - Sayı: 3, 127–132. https://ajindex.com/articles/551173

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