Journals / İstanbul Kanuni Sultan Süleyman Tıp Dergisi / 2014 / Cilt: 6 - Sayı: 1

Is preoperative D&C adequate for the determination of endometrial pathologies

Preoperatif yapılan dilatasyon ve küretaj endometrial patolojileri değerlendirmede yeterli midir?

Pages
14–19
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Furthermore preoperative D&C is an inadequate diagnostic tool for uterine focal lesions.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study was to compare outcomes of pre-hysterectomy dilatation, and cıurettage (D&C), and histopathological results of biopsied hysterectomy specimens in patients scheduled for hysterectomy with benign as well as malignant indications.
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Key Findings & Data:Material and Methods: The records of 144 patients on whom hysterectomy for benign indications as well as malignant indications were performed in the Division of Obstetrics and Gynecology, Bagcilar Training and Research Hospital between December 2011 and December 2012 were evaluated retrospectively.
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Conclusion & Impact:Furthermore preoperative D&C is an inadequate diagnostic tool for uterine focal lesions.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study was to compare outcomes of pre-hysterectomy dilatation, and cıurettage (D&C), and histopathological results of biopsied hysterectomy specimens in patients scheduled for hysterectomy with benign as well as malignant indications. Material and Methods: The records of 144 patients on whom hysterectomy for benign indications as well as malignant indications were performed in the Division of Obstetrics and Gynecology, Bagcilar Training and Research Hospital between December 2011 and December 2012 were evaluated retrospectively. Preoperative D&C and postoperative endometrial pathology results were compared. Results: The diagnosis at D&C was ‘insufficient tissue’ for 16 (11.1 %) patients. D&C failed to detect intrauterine disorders especially endometrial polyps (73.9 %) in premenopausal and postmenopausal women. Malignant patholo- gies were determined in curettage material in 3 (2 %) cases and hysterectomy specimens in 11 (7.6 %) cases. The malignancies determined in three patients were endometrial adenocarcinoma at D&C. Hysterectomy was reportedly indicated in 11 patients for malignant pathologies as follows; endometrial adenocarcinoma (n= 8), leiomyosar- coma (n=2), and endometrial stromal sarcoma (n=1). D&C failed to detect uterine sarcoma. Sensitivity (27.2 %), specificity (100 %), positive (100 %) and negative (94.5 %) predictive values, and accuracy (94.6 %) of dilatation and curettage material were also estimated as indicated within parentheses. Conclusion: Endometrial biopsy material retrieved blindly is clearly less reliable for the detection of endometrial malignant pathology. Furthermore preoperative D&C is an inadequate diagnostic tool for uterine focal lesions.

Özet

Amaç: Benign ve malign endikasyon nedeniyle histerektomi planlanan hastalarda, histerektomi öncesi yapılan dilatasyon ve küretaj (D&C) biyopsi sonuçları ile histerektomi materyalinin biyopsi sonuçlarını karşılaştırmayı amaçladık.Gereç ve Yöntem: Bağcılar Eğitim ve Araştırma Hastanesi Kadın Hastalıkları ve Doğum Kliniğinde Aralık 2011 veAralık 2012 yılları arasında benign ve malign nedenler ilehisterektomi yapılan 144 hastanın preoperatif D&C ve histerektomi spesmenlerinin histopatoloji sonuçları retros-pektif olarak değerlendirildi.Bulgular: Yüz kırk dört hastaya yapılan endometrial örneklemenin 16 (% 11.1) tanesinin patoloji raporu yetersiz olarak rapor edildi. D&C intrauterin lezyonları özellikle endometrial polipleri (% 73.9) belirlemekte başarısız oldu. Malign patoloji (endometrial adenokarsinom ve diğerleri), küretaj materyalinde 3 (% 2) olguda ve histerektomi materyalinde 11 (% 7.6) olguda saptandı. D&C’da 3 hastada rapor edilen malignitelerin hepsi endometrial adenokarsinomdu. Histerektomi piyeslerinin sonucunda rapor edilen 11 olgudaki malign patolojiler; 8 hastada endometrial adenokarsinom, 2 hastada leiomyosarkom ve 1 hasta- da endometrial stromal sarkom olarak saptandı. Histerektomi materyallerinde sarkom tanısı koyulan hastaların hiçbiri D&C yakalanamadı. Malign patolojiler için ise D&C sensivitesi % 27.2, spesifitesi % 100, pozitif prediktif değeri % 100, negatif prediktif değeri % 94,5 ve testin doğruluğu ise % 94.6 idi. Sonuç: Endometrial malign patolojiler için körlemesine alınan endometrial biyopsinin güvenilirliği azdır. Ayrıcahisterektomi öncesi D&C, intrauterin fokal patolojilerintanısında yetersiz kalmaktadır.

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Cite This Article

NAKİ, M. M., KARACAN, T., DAYAN, H., USTA, T. A. (2022). Is preoperative D&C adequate for the determination of endometrial pathologies. İstanbul Kanuni Sultan Süleyman Tıp Dergisi, Cilt: 6 - Sayı: 1, 14–19. https://ajindex.com/articles/551168

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