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Journals / İstanbul Kanuni Sultan Süleyman Tıp Dergisi / 2018 / Cilt: 10 - Sayı: 3

The Relationship Between Congenital Hypothyroidism and Neonatal Sepsis in Premature Infants

Prematürelerde Konjenital Hipotiroidi ile Neonatal Sepsis İlişkisi

Mehmet BÜYÜKTİRYAKİ
Ufuk ÇAKIR
Cüneyt TAYMAN
Ebru YARCI
Pages
100–105
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As is known during critical diseases, and sepsis thyroid hormones are suppressed, and this issue needs to be investigated further in the newborns in terms of sepsis, and its complications.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Thyroid hormones, and especially lower total triiodothyronin (T3), and thyroxine levels have been suggested to be predictors of bacterial sepsis in children, and newborns.The relationship between hypothyroidism and the frequency of sepsis and causative bacteria is not known especially in premature infants.
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Key Findings & Data:In this study, we aimed to investigate the relationship between groups with and without congenital hypothyroidism (CH) among very- low-birth-weight (VLBW) (0,05).
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Conclusion & Impact:As is known during critical diseases, and sepsis thyroid hormones are suppressed, and this issue needs to be investigated further in the newborns in terms of sepsis, and its complications.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Thyroid hormones, and especially lower total triiodothyronin (T3), and thyroxine levels have been suggested to be predictors of bacterial sepsis in children, and newborns.The relationship between hypothyroidism and the frequency of sepsis and causative bacteria is not known especially in premature infants. In this study, we aimed to investigate the relationship between groups with and without congenital hypothyroidism (CH) among very- low-birth-weight (VLBW) (0,05). Conclusion: IIn our study, we found that hypothyroidism did not cause any risk of sepsis and meningitis in VLBW preterm infants. As is known during critical diseases, and sepsis thyroid hormones are suppressed, and this issue needs to be investigated further in the newborns in terms of sepsis, and its complications.

Özet

Amaç: Tiroid hormonlarının, özellikle düşük total triiyodotironin (T3) ve tiroksin (T4) düzeylerinin çocuklarda ve yenidoğanlarda bakteriyel sepsisin öngörücüsü olduğunu ilerisürülmüştür. Yalnız, hipotiroidi olan hastalarda sepsis sıklığıve üreyen etkenlerin arasındaki ilişki özellikle prematürelerdebilinmemektedir. Çalışmamızda, çok düşük doğum ağırlıklı(ÇDDA; 0,05).Sonuç: Çalışmamızda ÇDDA prematürelerde hipotiroidinin,sepsis ve menenjit açısından risk oluşturmadığı bulundu.Kritik hastalık ve sepsis sırasında tiroid hormonlarının baskı-landığı bilinmekte olup, hipotiroidi olan yenidoğanlarda sepsisve komplikasyonları açısından daha fazla araştırılması gerekmektedir.

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Cite This Article

BÜYÜKTİRYAKİ, M., ÇAKIR, U., TAYMAN, C., YARCI, E. (2022). The Relationship Between Congenital Hypothyroidism and Neonatal Sepsis in Premature Infants. İstanbul Kanuni Sultan Süleyman Tıp Dergisi, Cilt: 10 - Sayı: 3, 100–105. https://ajindex.com/articles/551034

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