Journals / İstanbul Kanuni Sultan Süleyman Tıp Dergisi / 2020 / Cilt: 12 - Sayı: 3

Significant Vitamin D Deficiency in Children and Adolescents With Type 1 Diabetes Mellitus: A Cross- Sectional Study

Tip 1 Diabetes Mellituslu Çocuk ve Ergenlerde Anlamlı D Vitamini Eksikliği: Kesitsel Bir Çalışma

Pages
217–221
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Future studies are needed to verify our data and for a possible supplementation regimen for thesepatients.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Considering the fact that individuals with type 1 diabetes mellitus (T1DM) havemultiple risk factors, vitamin D sufficiency in childhood in this population is of particularconcern.
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Key Findings & Data:The aim of this study is to assess vitamin D status of T1DM patients in childhoodwith respect to their age groups.Method: A total of 212 type 1 diabetic children between ages of 1.5-18 years were screenedfor serum 25-hydroxyvitamin D [25(OH)D] levels from 29 December 2009 to 13 April 2010.Four age groups were copnstructed [14 years (n: 68)], and those groups were compared according to 25(OH)D status.
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Conclusion & Impact:Future studies are needed to verify our data and for a possible supplementation regimen for thesepatients.
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Considering the fact that individuals with type 1 diabetes mellitus (T1DM) havemultiple risk factors, vitamin D sufficiency in childhood in this population is of particularconcern. The aim of this study is to assess vitamin D status of T1DM patients in childhoodwith respect to their age groups.Method: A total of 212 type 1 diabetic children between ages of 1.5-18 years were screenedfor serum 25-hydroxyvitamin D [25(OH)D] levels from 29 December 2009 to 13 April 2010.Four age groups were copnstructed [14 years (n: 68)], and those groups were compared according to 25(OH)D status. Vitamin Dsufficiency, insufficiency, and deficiency were defined as 25(OH)D ≥30 ng/mL, 21-29 ng/mL,and ≤20 ng/mL, respectively. Body mass index of patients, HbA1c levels and daily insulindoses were recorded.Results: Vitamin D sufficiency rate was 34.9%, and deficiency rate was 42,9%. Vitamin Dlevels significantly decreased iwith aging; only 16.2% of >14 year-old patients had 25(OH)Dlevels of >30 ng/mL.Conclusion: We found that vitamin D deficiency is prevalent among type 1 diabetic childrenin our study, and especially adolescent diabetic patients were of special concern. Future studies are needed to verify our data and for a possible supplementation regimen for thesepatients.

Özet

Amaç: Tip 1 diabetes mellitus (T1DM) hastası bireylerin çoklu risk faktörlerine sahip olduğu gerçeği göz önüne alındığında, bu popülasyondaki D vitamini yeterliliğinin çocukluk çağında özel bir önemi vardır. Bu çalışmanın amacı, çocukluk çağındaki T1DM hastalarının vitamin D durumunu yaş grupları göz önüne alınarak değerlendirmektir. Yöntem: 1,5-18 yaşları arasındaki toplam 212 diyabetik çocuk 29 Aralık 2009 ila 13 Nisan 2010 tarihleri arasında serum 25-hidroksivitamin D [25(OH)D] seviyeleri için tarandı. Yaş gruplarına göre dört grup oluşturuldu [14 yaş (n: 68)] ve bu gruplar 25(OH)D durumuna göre karşılaştırıldı. D vitamini yeterliliği, yetersizliği ve eksikliği sırasıyla 25 (OH) D ≥30 ng/mL, 21-29 ng/mL ve ≤20 ng/mL olarak tanımlandı. Hastaların vücut kitle indeksi, HbA1c düzeyleri ve günlük insülin dozları kaydedildi. Bulgular: D vitamini yeterlilik oranı% 34,9, eksiklik oranı% 42,9 idi. Yaş ilerledikçe D vitamini düzeyi önemli ölçüde azaldı; > 14 yaşındaki hastaların yalnızca % 16,2’sinde 25 (OH) D> 30 ng/mL idi. Sonuç: Çalışmamızda, D vitamini eksikliğinin Tip 1 diyabetik çocuklarda yaygın olduğunu bulduk ve özellikle ergen diyabetic hastalarda daha dikkat çekici idi. Verilerimizi doğrulamak ve bu hastalar için olası bir takviye rejimini için ileri çalışmalara gereksinim vardır.

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Cite This Article

ÖNAL, H., ADAL, E., TAŞKIN, D. G., ERSEN, A. (2022). Significant Vitamin D Deficiency in Children and Adolescents With Type 1 Diabetes Mellitus: A Cross- Sectional Study. İstanbul Kanuni Sultan Süleyman Tıp Dergisi, Cilt: 12 - Sayı: 3, 217–221. https://ajindex.com/articles/550950

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