AI Summary & Key Takeaways
AI InsightOf 60 women with LSILthat underwent colposcopic biopsy, 13.3% (n=8) had CIN2/3.CONCLUSION: The results of the study suggest that routine cytological follow-up may be an appropriate method in themanagement of ASCUS instead of immediate colposcopy while immediate colposcopy cannot place repeat cytology for LSILin developing countries.
📌 3 Key Takeaways
Abstract
OBJECTIVE: Cervical cancer contributes to a significant global health burden with room for improvement of primary prevention methods. This study aimed to determine the prevalence of Turkish women with abnormal cytology and their management by comparing results from repeat cytological analysis with close follow-up and colposcopy.METHODS: A retrospective evaluation of 8738 women who underwent Pap smears at a single institution during 2011 wasperformed. Either repeat cytological analysis or colposcopic biopsy was used for follow-up evaluation of women who hadabnormal index cytology.RESULTS: From the 8670 women, 8259 of had normal cytology results (95.3%) and 411 women had abnormal cytology(4.7%) in the index Pap smear. The frequency of initial abnormal cytology was 65% (n=267), 27% (n=111), 3.4% (n=14),2.4% (n=10), 1.9% (n=8), and 0.3% (n=1) for atypical squamous cell of undetermined significance (ASCUS), low-gradesquamous intraepithelial lesion (LSIL), ASC cannot exclude high-grade intraepithelial lesion (ASC-H), high-grade SIL (HSIL),atypical glandular cells (AGC), and invasive cancer, respectively. Of the 267 women with initial ASCUS, 108 (40.4%) underwent repeat cytology analysis, 84 (31.5%) underwent colposcopic biopsy, and 75 (28.1%) were lost to follow-up. Onhistopathology, 8.3% (n=7) of patients had cervical intraepithelial neoplasm 2 (CIN2) on colposcopy. Of 60 women with LSILthat underwent colposcopic biopsy, 13.3% (n=8) had CIN2/3.CONCLUSION: The results of the study suggest that routine cytological follow-up may be an appropriate method in themanagement of ASCUS instead of immediate colposcopy while immediate colposcopy cannot place repeat cytology for LSILin developing countries.