Journals / İstanbul Kanuni Sultan Süleyman Tıp Dergisi / 2022 / Cilt: 14 - Sayı: 1

Role of Platelets and Indices in the Clinicopathological Features of Papillary Thyroid Carcinoma

Papiller Tiroid Karsinomunun Klinikopatolojik Özelliklerinde Trombositler ve İndekslerin Rolü

Pages
97–103
Publication Date
2022-10-18
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The preoperative PLT count, MPV, and PCT were significantly higher in patients with tumor size ≥ 1 cm (p=0.005, p=0.001, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, the potential relationship between platelet (PLT) count, PLT indices (mean platelet volume [MPV] and plateletcrit [PCT]), and clinicopathological features in patients with papillary thyroid cancer was evaluated.
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Key Findings & Data:Method: A total of 196 patients diagnosed with papillary thyroid cancer after total thyroidectomy were included in the study.
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Conclusion & Impact:The preoperative PLT count, MPV, and PCT were significantly higher in patients with tumor size ≥ 1 cm (p=0.005, p=0.001, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, the potential relationship between platelet (PLT) count, PLT indices (mean platelet volume [MPV] and plateletcrit [PCT]), and clinicopathological features in patients with papillary thyroid cancer was evaluated. Method: A total of 196 patients diagnosed with papillary thyroid cancer after total thyroidectomy were included in the study. The preoperative PLT, MPV, and PCT values of the patients were compared with the clinicopathological features of papillary thyroid cancer obtained from pathology reports. Results: The mean age of the study population was 46±12 years, and the male/female ratio was 29/167. The preoperative PLT count, mean thyroid-stimulating hormone, MPV, and PCT were 288±61 cells/L, 1.9±1.4 mIU/L, 10±0.93, and 0.30%±0.06%, respectively. The preoperative PLT count, MPV, and PCT were significantly higher in patients with tumor size ≥ 1 cm (p=0.005, p=0.001, p

Özet

Amaç: Bu çalışmada papiller tiroid kanserli hastalarda trombosit sayısı, trombosit indeksleri (Ortalama trombosit hacmi, trombositkrit) ve klinikopatolojik özellikler arasındaki potansiyel ilişki değerlendirildi. Yöntem: Total tiroidektomi sonrası papiller tiroid kanseri tanısı alan 196 hasta çalışmaya dahil edildi. Hastaların preoperatif PLT, MPV ve PCT değerleri ile patoloji raporlarındanelde edilen papiller tiroid kanserin klinikopatolojik özellikleri karşılaştırıldı. Bulgular: Çalışma popülasyonunun ortalama yaşı 46±12 yıl ve erkek/kadın oranı 29/167 idi. Preopratif trombosit sayıları ve ortalama TSH, ortalama trombosit hacmi ve trombositkrit değerleri sırasıyla 288±61 hücre/L, 1,9±1,4 (mIU/L), 10±0,93 ve 0,30±0,06 (%) idi. Tümör boyutu ≥1 cm olan hastalarda ameliyat öncesi trombosit sayısı, ortalama trombosit hacmi ve trombositkrit anlamlı olarak daha yüksekti (p=0,005, p=0,001, p

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Cite This Article

BÖLÜKBAŞI, H., YILMAZ, S., BOZKURT, M. A., YILDIRIM, E. O., OCAKOĞLU, A. (2022). Role of Platelets and Indices in the Clinicopathological Features of Papillary Thyroid Carcinoma. İstanbul Kanuni Sultan Süleyman Tıp Dergisi, Cilt: 14 - Sayı: 1, 97–103. https://ajindex.com/articles/550905

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