Journals / İstanbul Kanuni Sultan Süleyman Tıp Dergisi / 2022 / Cilt: 14 - Sayı: 1

The importance of blood urea nitrogen and hematological parameters according to endoscopic diagnoses and Forest Ulcer Groups in Upper Gastrointestinal System Bleeding

Üst Gastrointestinal Sistem Kanamalarında Endoskopik Tanılara ve Forrest Ülser Gruplarına Göre Kan Üre Nitrojen ve Hematolojik Parametrelerin Önemi

Pages
63–69
Publication Date
2022-10-18
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Lymphocyte values were statistically significantly higher in the group where peptic ulcer was detected (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: We aimed to investigate the cause and frequency of hemorrhage at the time of diagnosis of gastrointestinal bleeding in a gastroenterology clinic and analyzed the differences between some hematological parameters and blood urea nitrogen between ulcer and non-ulcer bleeding groups.
📊
Key Findings & Data:Method: We retrospectively reviewed the data of 372 upper gastrointestinal bleeding patients who were followed between 2009 and 2021.
💡
Conclusion & Impact:Lymphocyte values were statistically significantly higher in the group where peptic ulcer was detected (p
🔬Design:Review & Systematic Survey
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: We aimed to investigate the cause and frequency of hemorrhage at the time of diagnosis of gastrointestinal bleeding in a gastroenterology clinic and analyzed the differences between some hematological parameters and blood urea nitrogen between ulcer and non-ulcer bleeding groups. Method: We retrospectively reviewed the data of 372 upper gastrointestinal bleeding patients who were followed between 2009 and 2021. Patients were classified as ulcerated and non-ulcerated hemorrhagic groups. The ulcerated patients were further grouped as high-risk and low-risk subjects. Among patient norgroups, the difference between lymphocyte, hematocrit (Htc), white blood cell, neutrophil, platelet, mid platelet volume (MPV), red cell distribution width (RDW), and blood urea nitrogen (BUN) was analyzed. Results: The most common diagnosed bleeding is peptic ulcer. In ulcer cases, Forrest 3 group is the most common cause of hemorrhage. BUN values are directly proportional to Forrest scores. Lymphocyte values were statistically significantly higher in the group where peptic ulcer was detected (p

Özet

Amaç: Bu çalışmada, bir gastroenteroloji kliniğine üst gastrointestinal kanama ile başvuran hastaların kanama nedenleri ve sıklıkları incelendi. Ayrıca, ülser ve ülser dışı kanama grupları arasında hematolojik parametreler ile üre azotu arasındaki farklılıkların incelenmesi amaçlandı. Yöntem: Çalışmada 2009-2021 yılları arasında 372 üst gastrointestinal kanama hastalarının verileri retrospektif olarak incelendi. Hastalar ülsere bağlı ve bağlı olmayan kanamalı gruplar olarak analiz edildi ve bunlar da yüksek ve düşük riskli olarak sınıflandırıldı. Bu gruplarda ayrıca lenfosit, hematokrit, beyaz küre, nötrofil, trombosit, midplatelet volüm (MPV), kırmızı küre dağılım genişliği (RDW) ile kan üre azotu (BUN) arasındaki farklılığın analizleri yapıldı. Bulgular: Endoskopik olarak en sık kanama nedeni peptik ülserdir. Peptik ülser olguları arasında en sık Forrest 3 grubu kanama nedeni olarak ortaya çıktı (%33,1). Peptik ülserin olduğu grupta lenfosit düzeyleri istatistiksel olarak anlamlı derecede yüksekti (p

🔖

Cite This Article

ALKIM, H., İRAK, K., ŞAHİN, M., KÖKSAL, A. R., ALKIM, C., ŞAHİN, H. (2022). The importance of blood urea nitrogen and hematological parameters according to endoscopic diagnoses and Forest Ulcer Groups in Upper Gastrointestinal System Bleeding. İstanbul Kanuni Sultan Süleyman Tıp Dergisi, Cilt: 14 - Sayı: 1, 63–69. https://ajindex.com/articles/550878

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Wilkins T, Khan N, Nabh A, Schade RR. Diagnosis and management of upper gastrointestinal bleeding. Am Fam Physician 2012;85:469–76
  2. Laine L, Peterson WL. Bleeding peptic ulcer. N Engl J Med 1994;331:717– 27
  3. Katschinski B, Logan R, Davies J, Faulkner G, Pearson J, Langman M. Prognostic factors in upper gastrointestinal bleeding. Dig Dis Sci 1994;39:706–12. 4. van Leerdam ME, Vreeburg EM, Rauws EA, Geraedts AA, Tijssen JG, Reitsma JB, et al. Acute upper GI bleeding: Did anything change? Time trend analysis of incidence and outcome of acute upper GI bleeding between 1993/1994 and 2000. Am J Gastroenterol 2003;98:1494–9
  4. Cook DJ, Guyatt G, Salena B, Laine LA. Endoscopic therapy for acute non-variceal haemorrhage: A meta-analysis. Gastroenterol 1992;102:139–48
  5. Barkun A, Bardou M, Marshall JK. Consensus recommendations for managing patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med 2003;139:843–57
  6. Fujishiro M, Iguchi M, Kakushima N, Kato M, Sakata Y, Hoteya S, et al. Guidelines for endoscopic management of non-variceal upper gastrointestinal bleeding. Dig Endosc 2016;28:363–78
  7. Hreinsson JP, Kalaitzakis E, Gudmundsson S, Björnsson ES. Upper gastrointestinal bleeding: Incidence, etiology and outcomes in a population- based setting. Scand J Gastroenterol 2013;48:439–47
  8. Khamaysi I, Gralnek IM. Acute upper gastrointestinal bleeding (UGIB) - initial evaluation and management. Best Pract Res Clin Gastroenterol 2013;27:633–8
  9. D'Amico G, Luca A. Natural history. Clinical-haemodynamic correlations. Prediction of the risk of bleeding. Baillieres Clin Gastroenterol 1997;11:243–56
  10. Al-Naamani K, Alzadjali N, Barkun AN, Fallone CA. Does blood urea nitrogen level predict severity and high-risk endoscopic lesions in patients with nonvariceal upper gastrointestinal bleeding? Can J Gastroenterol 2008;22:399–403
  11. Adeva MM, Souto G, Blanco N, Donapetry C. Ammonium metabolism in humans. Metabolism 2012;61:1495–511
  12. Mardini H, Record C. Pathogenesis of hepatic encephalopathy: Lessons from nitrogen challenges in man. Metab Brain Dis 2013;28:201–7
  13. Häberle J. Clinical and biochemical aspects of primary and secondary hyperammonemic disorders. Arch Biochem Biophys 2013;536:101–8
  14. Stellato T, Rhodes RS, McDougal WS. Azotemia in upper gastrointestinal hemorrhage. A review. Am J Gastroenterol 1980;73:486–9
  15. Chalasani N, Patel K, Clark WS, Wilcox CM. The prevalence and significance of leukocytosis in upper gastro